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Name : kdsB (FTM_0734) Accession : YP_001891488.1 Strain : Francisella tularensis FSC147 Genome accession: NC_010677 Putative virulence/resistance : Virulence Product : 3-deoxy-manno-octulosonate cytidylyltransferase Function : - COG functional category : M : Cell wall/membrane/envelope biogenesis COG ID : COG1212 EC number : 2.7.7.38 Position : 798821 - 799573 bp Length : 753 bp Strand : + Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS DNA sequence : ATGGCTAATATCCATATTGTAATTCCTGCCAGGCTTAAATCAACTCGTCTACCAAATAAAATGCTGGCAGATATTGCCGG TAAGCCAATGATTCAGAGAGTCTATGAGCAAGTGACTAAATCAAAGTTTGATAGCATAATAATAGCTACAGATTCGCAAA AAATAAAAGATATCGCAGAGAGCTTTGATGCAAAAGTAGTTTTGACAAGAGATGATCATCAATCAGGAACAGATAGAATA GCAGAAGCAGTTACTAAATTAGGCTTTGCAGATGAAGACATTGTTGTAAATGTCCAAGGTGATGAGCCATTGATCCCTAT TGAAAATATCGAGCGAGCTGCGCAGTTATTGATAGACAAATCAGAAGCTGTAGTCTCGACGTTGTGTGAAAAAATCACAG ATGTAGAAGATATTTATAATCCTAATAATGTCAAAGTAGTTTTTGATAAAAATAACTATGCTTTATATTTTAGTAGAGCA TCTATTCCTTTTGAAAGAGGTTTTTCTGAGAAAGAGCAGATTAATATTTCAGAATTTTTTAGACATATTGGTATATATGC ATATCGAGTAGCTTTTTTAAAACATTATGCAGAACTTACAGTTTCACCAATTGAGAAATACGAAGCTCTTGAACAGCTAA GAGTCTTATATAATGGTTACAAAATCGCTATTGAGCAATCAGCTAAATCAACTCTTGCTGGTGTTGATACATTGCAAGAT TTAGAAAAAGTAAGGAAATTATTTAATGTTTAA Protein sequence : MANIHIVIPARLKSTRLPNKMLADIAGKPMIQRVYEQVTKSKFDSIIIATDSQKIKDIAESFDAKVVLTRDDHQSGTDRI AEAVTKLGFADEDIVVNVQGDEPLIPIENIERAAQLLIDKSEAVVSTLCEKITDVEDIYNPNNVKVVFDKNNYALYFSRA SIPFERGFSEKEQINISEFFRHIGIYAYRVAFLKHYAELTVSPIEKYEALEQLRVLYNGYKIAIEQSAKSTLAGVDTLQD LEKVRKLFNV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| kpsU | AAZ04469.1 | CMP-KDO synthetase | Virulence | PAI I APEC-O1 | Protein | 2e-41 | 43 |
| kpsU | YP_854332.1 | 3-deoxy-manno-octulosonate cytidylyltransferase | Not tested | PAI I APEC-O1 | Protein | 3e-41 | 43 |
| kpsU | CAE85213.1 | KpsU protein | Virulence | PAI V 536 | Protein | 4e-41 | 43 |
