Gene Information

Name : rph (FTM_0450)
Accession : YP_001891253.1
Strain : Francisella tularensis FSC147
Genome accession: NC_010677
Putative virulence/resistance : Unknown
Product : ribonuclease PH
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0689
EC number : 2.7.7.56
Position : 496465 - 497172 bp
Length : 708 bp
Strand : +
Note : RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs

DNA sequence :
ATGCGTCCAAGTGGTAGAAATAATGATCAACTACGTAATCTAAAAGTTACACATAATTTTACAAAACATGCCGAGGGCTC
TGTCCTTATTGAATTTGGAGATACTAAAGTTATCTGTACAGCTTCTGTAGTTGCAGGTGTACCAAAATTTAAAAAAGATA
GTGGTGAGGGTTGGCTAACAGCAGAATATGGCATGTTGCCGCGTTCAACTCATATGCGTATGGATAGAGAGGCAGCACGT
GGTAAGCAATCTGGAAGAACTCAAGAAATTCAGCGCCTGATAGGTAGAGCATTGCGTGCTAGTGTTGATCTTACAGCTAT
CGGGGAAAATACTATTAAGATTGATTGTGATGTGATTCAAGCTGATGGTGGTACGCGTACTGCATCGATTACCGGCGCAT
CATTAGCCATAGCTGATGCTATAGAATATATGAAACAAAATGGTATGTTAGATGAGCAGGCAAATCCACTATTATCACAA
GTGGCAGCAATATCTGTAGGTATTTATAATAACGAGCCAGTGCTTGATCTTGATTATGATGAAGATTCAAACGCAGAAAC
TGATATGAATGTAGTGATGAATTCAAATGGCGGTATAATCGAGATTCAAGGCACTGCTGAAGGCAAAGACTTCTCTGAAG
AAGAGTTTGCAAAAATGCTTGGTCTTGCTAAAAAAGGTATCAAAGAGATTTTTGCAACAGTATTCTAG

Protein sequence :
MRPSGRNNDQLRNLKVTHNFTKHAEGSVLIEFGDTKVICTASVVAGVPKFKKDSGEGWLTAEYGMLPRSTHMRMDREAAR
GKQSGRTQEIQRLIGRALRASVDLTAIGENTIKIDCDVIQADGGTRTASITGASLAIADAIEYMKQNGMLDEQANPLLSQ
VAAISVGIYNNEPVLDLDYDEDSNAETDMNVVMNSNGGIIEIQGTAEGKDFSEEEFAKMLGLAKKGIKEIFATVF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
rph YP_001800860.1 ribonuclease PH Not tested Not named Protein 9e-67 59