Gene Information

Name : lysU (FTM_1649)
Accession : YP_001892227.1
Strain : Francisella tularensis FSC147
Genome accession: NC_010677
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 1765212 - 1766942 bp
Length : 1731 bp
Strand : -
Note : -

DNA sequence :
TTGGGGCTACTAATTGCTAATGTGCAACAAATAATTACAGGGTTTAAAATGAGTAGTAAATTAAAAGATTTGATAAAAAC
AACGATAAAAGAATATTTAGAAGCTAATGATATCACAGTTAAAGATGCTATTAGAGGCAAGATTAGAGAGCAGATTAGTG
AGTTTTTAGGCGAGGTAAGCGAGATAAATGAGCAGGTTAAAGAACAAATTTCAGCGCTTGTGAAAAAGCATGTAACAGAA
TTACAAGAAAGCTCACAAATTGCTTTAAGAAAAGAAAAGCTAAAAACTTTAGCTCAGCAAAATAATGGCATAAGCCATCC
AAATAGTTTCCGAAGAAATGCTGTTGCTATAGAGTTACAGGCTCGCTATGCTGATAAGACTAAGCAAGAATTAGAAGAGC
TAGATAATAAACAACAATATAATTTGACAGGTAGAGTAGTTCTACGCCGTGTCATGGGTAAAGCATCTTTTATAACACTA
CAAGATTATACTGGTAGAATCCAAGTTTATCTAAAAAAGAGTGACTTGCCAGATGGGCAATATGAAACTTTTAAGAATCT
ATGTGACTTGGGTGATATAGTTGGTATTACTGGTACTATGTTTAAGACAAATACTGGTGAACTTTCTGTTGAAGCAAATC
ACTTTGAGATTTTGACAAAGGCAATTCGTCCTTTGCCTGATAAATTCCATGGTTTGGCAGATCAAGAAATGAGATATCGT
CAAAGATATGTTGATTTAATTACAAATGAAAAGGCAAGAGAAGTCTTTAAAGTACGTTCAAAAGTTGTGAACTTTATCCG
TAACTATTTTGATAGACTAGATTTTATGGAAGTAGAGACGCCGATGATGCATGTTTTGCAAGGTGGTGCTGCTGCTAAGC
CATTTAAAACTCATCACAATGCTTTGGATATGCCTTTATATTTGCGTATTGCTCCAGAACTTTATCTAAAAAGACTAGTT
GTTGGTGGTTTTGAGCGAGTTTATGAGATAAACCGTAATTTTAGAAACGAAGGTGTATCTTCACGCCATAATCCAGAATT
TACAATGCTAGAGTTCTATATAGCGTATGCTGATTATAATGACCTTATGGATCTAACAGAAGATATGCTATCTAAACTTG
TACAGGAAGTAATTGGTAGCGAGATACTTGAGTATGGTGAGTATAAAATCAACTTTGGTGGTAAGTACGAACGAATCTCA
ATGGTTGACTCAATTGTTAAGTATAATGATGATATTACCAAAGAAGATTTAGTAACATTTGAATCTGCTAAAAAGATTGC
TGAGAAACTAAAAATAAAAGTTGAAGCTTACCATGAACTTGGACATTTGATAAACGAAATATTTGAAGAAACTGTCGAGC
ATCAGCTTATTCAACCGACATTTATTACAGATTATCCAGCTGTAGTTTCACCATTGGCACGTAGACAAGATGGTAACCCT
GAGTTTACCGATAGATTTGAGTTCTTTATTGGAGCACGTGAAGTTGCTAACGGCTTCTCTGAGCTAAATGATGCTGAAGA
TCAAGCAGAGCGTTTCAGAAAACAGGTTGAAGCTGCGGCATCTGGAGATGATGAAGCTATGCCTTATGACAAAGACTATA
TCCGCGCACTAGAGTATGGTATGCCTCCTACAGCGGGACAAGGAATCGGTATTGATAGACTGGTAATGTATCTAACAAAC
TCTCAATCAATTAGAGATGTGATTCTATTTCCGCATATGAAGCCTGAGTAA

Protein sequence :
MGLLIANVQQIITGFKMSSKLKDLIKTTIKEYLEANDITVKDAIRGKIREQISEFLGEVSEINEQVKEQISALVKKHVTE
LQESSQIALRKEKLKTLAQQNNGISHPNSFRRNAVAIELQARYADKTKQELEELDNKQQYNLTGRVVLRRVMGKASFITL
QDYTGRIQVYLKKSDLPDGQYETFKNLCDLGDIVGITGTMFKTNTGELSVEANHFEILTKAIRPLPDKFHGLADQEMRYR
QRYVDLITNEKAREVFKVRSKVVNFIRNYFDRLDFMEVETPMMHVLQGGAAAKPFKTHHNALDMPLYLRIAPELYLKRLV
VGGFERVYEINRNFRNEGVSSRHNPEFTMLEFYIAYADYNDLMDLTEDMLSKLVQEVIGSEILEYGEYKINFGGKYERIS
MVDSIVKYNDDITKEDLVTFESAKKIAEKLKIKVEAYHELGHLINEIFEETVEHQLIQPTFITDYPAVVSPLARRQDGNP
EFTDRFEFFIGAREVANGFSELNDAEDQAERFRKQVEAAASGDDEAMPYDKDYIRALEYGMPPTAGQGIGIDRLVMYLTN
SQSIRDVILFPHMKPE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 3e-138 56
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 5e-85 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysU YP_001892227.1 lysyl-tRNA synthetase VFG1668 Protein 2e-138 56