Gene Information

Name : purA (FTM_1639)
Accession : YP_001892221.1
Strain : Francisella tularensis FSC147
Genome accession: NC_010677
Putative virulence/resistance : Unknown
Product : adenylosuccinate synthetase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0104
EC number : 6.3.4.4
Position : 1751807 - 1753093 bp
Length : 1287 bp
Strand : -
Note : catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis

DNA sequence :
ATGTCAAATATCGTAATCGTAGGCGCTCAGTGGGGCGATGAAGGTAAAGGTAAAATAGCAGATACTTTAGCTGAGAAAGC
CGATTTGGTTGTTCGTTATCAAGGTGGTAATAACGCTGGTCATACATTGGTTGTAAATGGTAAGAAGACATTTCTTCATT
TAATACCTTCAGGTGTTTTGCATCAGCATACAAAATGTGTAATTGGTCATGGCGTGGTTTTAGATCCTGTTGCCTTAGAT
GAGGAAATTACACGTCTACAAGCAAAAGGTATAGCAATTTCAGCAGAGAATTTATTTGTTTCTGAGTCTTGTACGATTAT
TACTTCTTATCATAAACTTTTAGATGCAGTTAGAGAAAGTAACACTAGTGAGAAAATAGGTACGACTGGTAAAGGTATTG
GTCCAGCATACGAGGATAAAGTATCGCGTAAAGGTATTAAATTTAAGCATCTATTTGATAAGGATTTATTAAGATCAAGG
TTAGCAATCTCTTTGGCAGAGAAAGAAACTTTATTTAGAGATTTATATAAAGTCGAATATCCAACACTAGAACAAGAATT
TGATAAGCTTTTTGCTTTGGGTCAAAAACTTAAACAGTATGCAGCAGATACTTTTTCAATAATAGATAAAGCAATTGCAG
CGGGTAAGAATGTTGTTTATGAAGGTGCACAAGGTGTGCTTTTAGATGTTGATTATGGTACTTATCCATTTGTGACATCT
TCTAATACTTCAGTGGCGGGAGTATATTCTGGTGCAACCACTGCCGGACATGGTTTCGATCATGTGATTGGGATTACAAA
AGCTTATACTACAAGAGTTGGTGAAGGACCTTTCCCAACAGAGCTTTTTGATGATGTTGGTAAATTTATTCAGCACAAAG
GTGGCGAGATAGGTGTGACAACTGGTAGAATTCGTAGGTGTGGTTGGTTAGATTTACCTCTTTTAAAATACTCAGCAAAA
TGCTCAAACTTAACATCAATAGCCTTAACAAAGGTTGATGTTTTATCTGATATGGACACTCTAAAAGTTTGTATTGGTTA
TAAGTATGAGGGCAAAGAAATATATTGTGCTTATCCAGGAATAGATCTTTACAAAGTAGAGCCAATTCTTGTCGAAATGG
AACCGTTTTCTATAGATGAAACAGTAACAAAAGATAATATGCCAGCTGCTCTTAAGACATATCTTGAGACTATAGAGAAT
CACGTTGGTATTCCAATATCTTCATTAGCTTATGGACCATCTAGAGAACAAATTTTATTCTTTGAGGATTATTTCAAAAA
GGGTTAA

Protein sequence :
MSNIVIVGAQWGDEGKGKIADTLAEKADLVVRYQGGNNAGHTLVVNGKKTFLHLIPSGVLHQHTKCVIGHGVVLDPVALD
EEITRLQAKGIAISAENLFVSESCTIITSYHKLLDAVRESNTSEKIGTTGKGIGPAYEDKVSRKGIKFKHLFDKDLLRSR
LAISLAEKETLFRDLYKVEYPTLEQEFDKLFALGQKLKQYAADTFSIIDKAIAAGKNVVYEGAQGVLLDVDYGTYPFVTS
SNTSVAGVYSGATTAGHGFDHVIGITKAYTTRVGEGPFPTELFDDVGKFIQHKGGEIGVTTGRIRRCGWLDLPLLKYSAK
CSNLTSIALTKVDVLSDMDTLKVCIGYKYEGKEIYCAYPGIDLYKVEPILVEMEPFSIDETVTKDNMPAALKTYLETIEN
HVGIPISSLAYGPSREQILFFEDYFKKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
purA YP_281500.1 adenylosuccinate synthetase Not tested Not named Protein 5e-89 46