Gene Information

Name : serS (FTM_1344)
Accession : YP_001891965.1
Strain : Francisella tularensis FSC147
Genome accession: NC_010677
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1441817 - 1443097 bp
Length : 1281 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTTGATGCTAAATATATTAAGGATAATTTACAACAAGTTGCTGAAAAGCTTGCAACTAGAGGTTATCAATTTGATAT
AGCCGAATTTGAAGCCCAAGAGCAAAAAAGAAAACATCTTCAAGAAAGAACTCAGGATCTACAATCACAACGTAATACTA
TTTCAAAAGAAATAGGCCAAAAAAAAGCTAAAGGTGAAGATACTAGTGATATCTTTGCTAAAGTTAATCAAATTAATGAA
GAACTAAAAATTATTGAAAAAGAGCTCAAAGACCTACAAGATACTATAAATCAAACACTATTATCAATGCCAAACCTTCC
TGCTGATGACGTCCCTGTTGGTAAAGATGAGAATGATAATGTAGAAATAAGAAGATGGGGAACTCCACGTGAGTTTCATC
CTGAAGCACCTGCAAAAGATCATTCTGATATTGGTGAAATCCTCAAAATGATTGATTTTAAAGCCGCTGCTAAAGTTACT
GGCAGCCGTTTTATGGTCCTGAAAAATAAGATTGCTAAACTACACCGCGCTCTATCACAGTTTATGCTTGATCTGCATAC
AGAAAAACATGGTTATGAAGAATTATATGTGCCATATCTAGTCAATAATGATAGTTTATATGGTACTGGACAATTACCAA
AATTTGCTGCTGATCTTTTTAAGCTTGAGGGAGATTTTGAATATAGTCTAATACCTACAGCAGAGGTGCCAATCACTAAT
CTAGTAAGGGATGAAATTTTAGATACAGAAACTTTACCTAGATACTATACAGCTCACACTCCTTGCTTTAGAAGTGAAGC
TGGTTCATATGGCCGTGATACTAAAGGTATGATTCGTCAACACCAGTTTGAGAAAGTCGAGTTAGTACATATCACTACTG
CAGATAAAGGTGAAGAATCTCTAGAATTACTCACATCACATGCTGAAAAAGTCTTACAAAAACTTAACTTACCATATAGA
GTGATGAAACTATGTACTGGTGATATGGGCTTTAGCGCTAAAAAAACTTATGATTTAGAAGTATGGCTCCCATCACAAAA
TACTTATAGAGAAATATCTTCATGTAGCTGGTGTGGAGATTTCCAAGCTCGTCGTATGAAAGCTCGACACAAAAATCCAA
GTATGAAGAAACCAGAATTAGTCCATACTCTAAATGGTTCTGGTTTGGCTGTAGGTAGAACATTATTAGCTATTATTGAA
AATTATCAACAAGAAGATGGTTCTATTATGGTTCCCGATGCTCTTATCAAGTATATGGGCGGAATTTCAGTTATTAAGTA
A

Protein sequence :
MLDAKYIKDNLQQVAEKLATRGYQFDIAEFEAQEQKRKHLQERTQDLQSQRNTISKEIGQKKAKGEDTSDIFAKVNQINE
ELKIIEKELKDLQDTINQTLLSMPNLPADDVPVGKDENDNVEIRRWGTPREFHPEAPAKDHSDIGEILKMIDFKAAAKVT
GSRFMVLKNKIAKLHRALSQFMLDLHTEKHGYEELYVPYLVNNDSLYGTGQLPKFAADLFKLEGDFEYSLIPTAEVPITN
LVRDEILDTETLPRYYTAHTPCFRSEAGSYGRDTKGMIRQHQFEKVELVHITTADKGEESLELLTSHAEKVLQKLNLPYR
VMKLCTGDMGFSAKKTYDLEVWLPSQNTYREISSCSWCGDFQARRMKARHKNPSMKKPELVHTLNGSGLAVGRTLLAIIE
NYQQEDGSIMVPDALIKYMGGISVIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 3e-101 55