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Name : secA (CLL_A0520) Accession : YP_001884726.1 Strain : Clostridium botulinum Eklund 17B Genome accession: NC_010674 Putative virulence/resistance : Unknown Product : preprotein translocase subunit SecA Function : - COG functional category : U : Intracellular trafficking, secretion and vesicular transport COG ID : COG0653 EC number : - Position : 514075 - 516585 bp Length : 2511 bp Strand : + Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap DNA sequence : ATGGGATTATTAAGTGCCGTATTTGGAACATATAGTGAAAGAGAAGTAAAGAGAATTAGACCTATTGTCAGCAAAATAAA TGAATTAGATGAAGTCATGCAAAAACTTTCAGATGATGAATTAAAGGCAAAGACTGTAGAGTTTAAAGAAAGACTTAATA ATGGTGAAACTGTAGATGATATTTTACCAGAAGCATTTGCTGTAGTTAGAGAAGCATCTAAAAGAGTGTTAAATATGAAG CATTATGATGAACAACTTATTGGTGGAATTGTTTTACATCAAGGTAGAATAGCTGAAATGAAGACAGGAGAAGGTAAAAC ATTAGTTGCAACTTTACCAGCATATTTAAACGGATTAACAGGCAAAGGTGTTCATATAATAACAGTTAATGATTATCTTG CAAAAAGAGATGCTGAACAAATGGGAGAATTATATGGCTTTTTAGGATTAACAACAGGTGTTATTGTTCATGAATTAACT AATGAACAAAGAAGAGAAGCATATAACTCAGATATAACTTATGGAACAAATAATGAATTTGGTTTTGATTATTTAAGAGA TAACATGGTTATATATAAGGAAGAAAGAGTTCAAAGAAAACTGAATTTTACTATAGTAGATGAAGTTGACTCAATATTAA TTGATGAAGCTAGAACTCCACTTATAATTTCTGGTCAAGGAGAAAAGTCTACAGAATTTTACAAAGTAGCAGATTATTTT GTAAAAACATTAGTAAAAGAAAAAGATTATACAATAGATGAAAAAGCTAATGCAGTAATGCTAACTGATGAAGGTTTCCA TAAAGCAGAACAAACTTTTAAAGTAGAAAATTATGCAGATGCTGAAAATGTAGAATTACAACATTATGTTACTCAAGCGT TAAAAGCTAACTATGCAATGAGAAGAGATAAAGATTACATGGTTAAAGATGGAGAAGTAATAATTGTTGACGAATTTACA GGAAGACTTATGGAAGGAAGACGATATTCAGATGGTCTTCATCAAGCAATAGAAGCTAAGGAAAATGTTAAAATTGCAAG AGAATCTAAAACATTAGCAACTATTACATTCCAAAATTACTTCAGAATGTATGAAAAATTATCAGGAATGACAGGTACAG CATTAACAGAAGAAAATGAATTTAGAGAAATTTATGGATTAGATGTTATTGTTGTTCCAACTCATAAGCCAGTTGTTAGA ATAGATAATCCTGATTTAGTATTTAAGAGTGAAAAAGGAAAGATCATGGCTGTTGTAGATGAGATAGCAAAAGCACATGA AGTAGGGCAACCAGTATTAGTTGGTACTGTAAGTATTGAAAAATCAGAATTGATTTCAAGTATGCTTAAGAAAAAAGGAG TTCCACATCAAGTTTTAAATGCGAAATTCCATGAACAAGAAGCAGAAATAATAACACATGCTGGTGAAAAAGGTATGGTT ACTATAGCCACTAATATGGCTGGTAGAGGTACTGATATTAAACTTGGAGAAGGTGTTCTTGAAATTGGTGGACTTAAGAT AATAGGTACTGAAAGACATGAATCAAGAAGAATAGATAACCAATTAAGAGGACGTTCTGGTAGACAAGGAGACAGTGGAG AATCAACATTCTTTATTTCATTAGAAGATGATTTAATGAGAATTTTTGGATCAGAAAAGATTCAAGGTGTTGTTGAAAAA CTTGGTCTTGAAGAAGATGAAGCAATTGAAAGTAAACTTGTTTCTAAGTCTATAGAAAATGCTCAAAAGAAGGTTGAAGG TAATAACTTTGATATAAGAAAAACATTATTAGGATATGATGATGTTATGAATAAACAAAGAGAAGTTATCTACAAACAAA GAGCAGAAGTTCTTGAAGGTGAAGATGTAAAAGAAGAAATATTACATATGCTAAGAGATGTAATATCAGATGCAGTTGAT ACTCATATCAAAGAAGATGCTGAAGATTATAGAGAAAGTTTCTTATATCTAATATCTTATTTAAATGATATATGCATACC AACAAATGAAGTTAATTTACCTGCACTTACAGAGATGTCAAAAGAAGAAATCATAGATCATTTATATGATGTTGCAGTTA AAAGTTACGAAGATAAAGAAGCTGAATTCACATCAGAAAGATTAAGAGAAATAGAAAGAGTTGTTCTTTTAAGATCTGTT GATACAAAATGGATGGATCACATTAACAATATGGATAACTTAAAACAAGGTATTGGGCTTAGAGCATTCAAACAAGTAGA TCCTGTTCAAGCGTATCAAATGGAAGGTAGCGCTATGTTTGAAGAAATGATAGATTCTATTAAGAAGGAAACTGTAAAGA TGTTACTCCATGTCAAAGTGGAAAGAGCACCTGAAAGAGTTAGAGTTGCGCAAGAAACAAATGCCGTACACGGAGATAAG CCATCAGCTCCAGTAGGACCAGTTAGAAATCTTAATAAATTTGGAAGAAATGACGTATGTCCATGCGGAAGTGGAAAGAA ATTTAAAAATTGTTGTGGTAGAGAAGCTTAA Protein sequence : MGLLSAVFGTYSEREVKRIRPIVSKINELDEVMQKLSDDELKAKTVEFKERLNNGETVDDILPEAFAVVREASKRVLNMK HYDEQLIGGIVLHQGRIAEMKTGEGKTLVATLPAYLNGLTGKGVHIITVNDYLAKRDAEQMGELYGFLGLTTGVIVHELT NEQRREAYNSDITYGTNNEFGFDYLRDNMVIYKEERVQRKLNFTIVDEVDSILIDEARTPLIISGQGEKSTEFYKVADYF VKTLVKEKDYTIDEKANAVMLTDEGFHKAEQTFKVENYADAENVELQHYVTQALKANYAMRRDKDYMVKDGEVIIVDEFT GRLMEGRRYSDGLHQAIEAKENVKIARESKTLATITFQNYFRMYEKLSGMTGTALTEENEFREIYGLDVIVVPTHKPVVR IDNPDLVFKSEKGKIMAVVDEIAKAHEVGQPVLVGTVSIEKSELISSMLKKKGVPHQVLNAKFHEQEAEIITHAGEKGMV TIATNMAGRGTDIKLGEGVLEIGGLKIIGTERHESRRIDNQLRGRSGRQGDSGESTFFISLEDDLMRIFGSEKIQGVVEK LGLEEDEAIESKLVSKSIENAQKKVEGNNFDIRKTLLGYDDVMNKQREVIYKQRAEVLEGEDVKEEILHMLRDVISDAVD THIKEDAEDYRESFLYLISYLNDICIPTNEVNLPALTEMSKEEIIDHLYDVAVKSYEDKEAEFTSERLREIERVVLLRSV DTKWMDHINNMDNLKQGIGLRAFKQVDPVQAYQMEGSAMFEEMIDSIKKETVKMLLHVKVERAPERVRVAQETNAVHGDK PSAPVGPVRNLNKFGRNDVCPCGSGKKFKNCCGREA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| secA2 | YP_006310687.1 | preprotein translocase subunit SecA2 | Not tested | FWisland_3 | Protein | 3e-132 | 41 |
