Gene Information

Name : dnaB (CLL_A3580)
Accession : YP_001887714.1
Strain : Clostridium botulinum Eklund 17B
Genome accession: NC_010674
Putative virulence/resistance : Unknown
Product : replicative DNA helicase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : 3.6.1.-
Position : 3778157 - 3779494 bp
Length : 1338 bp
Strand : -
Note : unwinds double stranded DNA

DNA sequence :
TTGGAATCACAAGTTATGAGAACTTTACCTCAGAGCATAGAAGCTGAACAATCGGTAATAGGATCTATGATTATAGATAA
ATCTGCTATTGCTAAAGTTTTAGAAAGCTTGGAAGAAGAAGATTTCTATAGAGATGGCCATAAAGTAATATTTAGAGCTA
TATTAGATATGTTTAGAAAAGACATGGGTGTAGATTTAATTACTTTATTGGAAAATTTAAAAAGTACGGAAATGCTTGAA
AGAGCAGGTGGAGTAACTTATATAACAGAAATAAGTGCATCAGTTCCTACTACTGCTAATTTATCTTCTTATATAAAAAT
AGTAGAAGAAAAGTCAGTTTTAAGAAAACTTATAAAAGCGTCAACATCGATAATAGAATCCAGCTATAATAATCAAGGCG
AAGTTGAAAATGTATTAGACGGAGCTGAAAAAAGAATATTTGATATAGCTGAAAAGAAAACATCAAAGGATTTTGAACCG
CTAAGTGATGTCTTAGAAAGAGGTTTTCTTGAAATAGAAAGACTTTTTAATAATAGGGGTGAAATTACAGGTGTAGGATC
TGGTTTTTCAGATTTAGATTCTAAAACATCAGGATTTCAAAAAGGTGATATGATTCTTATTGCTGCTAGACCATCTATGG
GTAAGACTACATTTGCATTAAATATAGCAGAGCATGCGGCGTTAAGAGAAGGAAAAAGCGTAGTTGTATTTTCTTTAGAA
ATGTCAAAAGAACAATTAGCATACAAATTGCTTTGTTCTGAAGCAAATGTTGATATGTTAAGACTTAGAACAGGTGAGTT
AGATGATAAGGATTGGGAGAACATAGCTAGAGCGACAGGTCCATTATCAAAAGCAAAAGTTTATATAGATGATACTGCAG
GGGTTTCAGTTATGGAAATGAGATCTAAATGTAGAAGATTAAAAATGGAATATGGAATAGATTTAATAGTTATAGATTAC
TTGCAACTTATGTCTGGAAGTACTAGTAGTGATAATAGACAACAAGAAGTGTCAGAAATATCAAGATCGATAAAAGCACT
GGCAAAGGAAATGGAATGTCCAGTTATAGCATTATCACAATTATCGCGTGCTCCAGAACAAAGAGCAGATCATAGACCAA
TGTTATCTGATTTAAGAGAATCTGGTTCTATAGAACAAGATGCTGACATTGTTATGTTCTTATATAGAGATGAGTATTAT
GACAAAGAAACTGAAGATAAGAATATTGCTGAATGCATAATAGCTAAACAAAGAAATGGTCCAGTGGGAACAGCTAAACT
CGCGTGGCTTGGTCAATTCAGTAAATTTGGGAATTTAGATGTTATTCATAAAGAATAA

Protein sequence :
MESQVMRTLPQSIEAEQSVIGSMIIDKSAIAKVLESLEEEDFYRDGHKVIFRAILDMFRKDMGVDLITLLENLKSTEMLE
RAGGVTYITEISASVPTTANLSSYIKIVEEKSVLRKLIKASTSIIESSYNNQGEVENVLDGAEKRIFDIAEKKTSKDFEP
LSDVLERGFLEIERLFNNRGEITGVGSGFSDLDSKTSGFQKGDMILIAARPSMGKTTFALNIAEHAALREGKSVVVFSLE
MSKEQLAYKLLCSEANVDMLRLRTGELDDKDWENIARATGPLSKAKVYIDDTAGVSVMEMRSKCRRLKMEYGIDLIVIDY
LQLMSGSTSSDNRQQEVSEISRSIKALAKEMECPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADIVMFLYRDEYY
DKETEDKNIAECIIAKQRNGPVGTAKLAWLGQFSKFGNLDVIHKE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dnaB2 YP_001402701.1 replicative DNA helicase Not tested YAPI Protein 2e-78 42
api2 CAF28476.1 putative DNA binding protein with DNA-dependent ATPase activity Not tested YAPI Protein 1e-78 42
unnamed ABR13456.1 replicative DNA helicase Not tested PAGI-5 Protein 3e-81 42
PMI2640 YP_002152342.1 DNA helicase Not tested Not named Protein 2e-74 42
STY4522 NP_458617.1 DNA helicase Not tested SPI-7 Protein 2e-73 42
t4227 NP_807829.1 DNA helicase Not tested SPI-7 Protein 2e-73 42
dnaB2 YP_001007676.1 putative DNA helicase Not tested YAPI Protein 1e-74 41