Gene Information

Name : hemC (CLL_A2907)
Accession : YP_001887094.1
Strain : Clostridium botulinum Eklund 17B
Genome accession: NC_010674
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 2988062 - 2988934 bp
Length : 873 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAATGAATTAATAATAGCAACTAGAAAAAGTAAGTTGGCTCAAGTTCAAACTGAAATAATTATGGGAAAATTGAAATC
AAAATTTAATATAGATAGTAAAAAATTACTTATAGTAACTGAGGGTGACAGAAAGTTAGATGTTTCATTAAATAAAATAG
GTGGTAAGGGACTTTTTGTTAAGGATATAGAACTTGCTCTTTTAAATAAGGAAGCTCATGCTGCAGTTCATAGTATGAAA
GATGTTCCTTTTGAAGTTAGTAGTGAATTTGAAATTACAGCTATAACAGGAAGAGAAGATATAAGGGATGTATTTATTTC
AAATGGAGATATCTCATTTAAAGATATTAAAAAAGGCGCTAAAGTAGGAACAAGTAGTATAAGAAGAGCAGCACAACTAA
AACTTCTAAGAAGTGATTTAGAGATAGTACCTATAAGAGGCAATGTTCAAACTAGATTAAAGAAAATGGAAGAACAAAAT
TTAGATGGAATCGTGCTAGCAGCAGCAGGTCTTAAAAGACTTGGTGATGAAAATTTAATAACAGATTATTTTGATCCAAA
AGAATTTTTACCAGCAGTTTCTCAAGGGGCACTTGGAATTGAGTGTTTAAAAGATGGTGATGCCAATAAATATTTTGAAG
CTTTAATAGATGCAGAAGCAACTTTAACTGTGGAAGCTGAAAGAAGTTTTATGAAAGAATTACAAGGAGATTGTCATAGC
CTTATTGGAGCTTATTCTGAAATTCAAGGTGATGATTTATATATGATTGGAATATATGATATAGGTGGAAAAATAGTTAA
AAAAGATATTTTAGGATGCAAAACTAATAATATTGAATTAGGAAAGAAATTAGCACAAAAAATATTAGGATAA

Protein sequence :
MNELIIATRKSKLAQVQTEIIMGKLKSKFNIDSKKLLIVTEGDRKLDVSLNKIGGKGLFVKDIELALLNKEAHAAVHSMK
DVPFEVSSEFEITAITGREDIRDVFISNGDISFKDIKKGAKVGTSSIRRAAQLKLLRSDLEIVPIRGNVQTRLKKMEEQN
LDGIVLAAAGLKRLGDENLITDYFDPKEFLPAVSQGALGIECLKDGDANKYFEALIDAEATLTVEAERSFMKELQGDCHS
LIGAYSEIQGDDLYMIGIYDIGGKIVKKDILGCKTNNIELGKKLAQKILG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 5e-46 43
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 5e-46 43