Gene Information

Name : CLL_A2808 (CLL_A2808)
Accession : YP_001886995.1
Strain : Clostridium botulinum Eklund 17B
Genome accession: NC_010674
Putative virulence/resistance : Virulence
Product : tetanolysin O
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2887772 - 2889580 bp
Length : 1809 bp
Strand : +
Note : identified by match to protein family HMM PF01289

DNA sequence :
ATGAAAACTACTAAAAAACTTCTCAAATCATTTGCTCAAGGATTATTAGCGGTTATGCTTATCAATGGATTTTCATATAT
TAGTGATTTTAAAACTAATAATAATGTTTTTCTATCAAACATAACAGAAAATAATTCCGAAAAAGAAATTACGGATAAAA
ATATAGTTGCTGAAAATATTAGTGATGAAACAAAAAATGTTGCATCAGATAATAAAACAGATAATATTTTATCTGAAAAA
AATGTATTAGATGAGGAAACACAAACAGATGATGACTTATTAAATACAGATTCTGTACAAACTATTAATCCCATTACTAT
TAACCCTATAGTTGATCCTATCGAATCTATTGAAGAACCAATTATAGAAGATATACCTCTTATAAGAGATACTTTGAAAA
ATGAGATTAATGATATTGATAAAAATATCTATGGCTTATCATATAACCCTGATAAGATACTATCTTCAAAAGGTGAAAGC
ATTGATAGCTTTGTACCTGCTGAAGGTTTTGATGCTCCAAATAAATATATTGTAGTAAAAAGAGAAAAGAAAAGTATATC
TGACTCTACTGCAGATATTTCAATAATAGATTCAATAAATGATAGAACTTACCCTGGTGCTATTCAACTTGCAAATAGAA
ATCTTGTTGAAAATAAACCTGATATAATCTCTTGTAAAAGAAAACCAATTACTATAAGTGTTGATTTACCTGGTATGAGT
GATGATGGCAGTAAAGTTGTTAATTCACCAACATATTCTACTATTAACGCTTCAATAAATTCCTTATTAGATACATGGAA
TACTAAATATTCATCTAAATATACTATTCCTACAAGAATGAGTTACACTGATGCTATGGTCTATAGTAAATCTCAACTTT
CTACAATGTTTGGTTGCAATTTAAAAATTTTAGATAAAGCATTGAATATAGATTTTAATTCTATATTTAAAGGCGAAAAA
CAAACTATGGTTGTTGCATATAAACAAATCTTCTATACAGTAAGTGTAGATGCACCTGAAAAACCTTCAGATGTATTTGG
TGATAATGTAAGCTTTGAGGAATTAGCTTTAAAAGGTGTAAATAATGAAAACCCACCTGCTTATGTTTCAAACGTTGCAT
ATGGTAGAACAATTTATGTAAAACTTGAAACAACTTCTAAGAGTGCAAATGTTAAAGCAGCATTTAAAGCCTTAATATCT
AACCAAGATATTAGTGGTAATACAGAATATGAAGATATTCTAGATCAAAGTTCATTTACAGCTACAGTGCTTGGTGGTGG
TGCTGAGGAGCATAACAAAGTAATTACTAAGGATTTTAATGAAATAAGAAATATTATACAAAATAACTCAGTATATAGCC
CTAAAAATCCTGGGTATCCTATTTCATATACAAGTACATTTTTAAAAGATAATAGAATTGCCACTGTAAATAATAAAACA
GACTATATAGAAACAACTGCAACAGAATATACAAATGGTAAAATAATACTTGATCATAGTGGTGCTTATGTTGCTCAATT
TGAAGTGACTTGGGATGAAGTTAGTTATGATAAAGACGGTAATGAAATAATAGAACATAAAGCTTGGTCTGGAAATGATC
GAGATAAAACTGCTCATTTTAACACAGAAATATATCTAAAAGGAAATACTAGAAATATATGTGTTAAGGCATGGGAATGT
ACAGGCCTTGCATGGGAATGGTGGAGACAGGTTATAGATGCTCAGAATATACCACTAGTAAAAGAGAGAACATTTTCAAT
ATGGGGTACAACATTGTATCCTAAAAAATCTGTTGAACCAGAAATTTAA

Protein sequence :
MKTTKKLLKSFAQGLLAVMLINGFSYISDFKTNNNVFLSNITENNSEKEITDKNIVAENISDETKNVASDNKTDNILSEK
NVLDEETQTDDDLLNTDSVQTINPITINPIVDPIESIEEPIIEDIPLIRDTLKNEINDIDKNIYGLSYNPDKILSSKGES
IDSFVPAEGFDAPNKYIVVKREKKSISDSTADISIIDSINDRTYPGAIQLANRNLVENKPDIISCKRKPITISVDLPGMS
DDGSKVVNSPTYSTINASINSLLDTWNTKYSSKYTIPTRMSYTDAMVYSKSQLSTMFGCNLKILDKALNIDFNSIFKGEK
QTMVVAYKQIFYTVSVDAPEKPSDVFGDNVSFEELALKGVNNENPPAYVSNVAYGRTIYVKLETTSKSANVKAAFKALIS
NQDISGNTEYEDILDQSSFTATVLGGGAEEHNKVITKDFNEIRNIIQNNSVYSPKNPGYPISYTSTFLKDNRIATVNNKT
DYIETTATEYTNGKIILDHSGAYVAQFEVTWDEVSYDKDGNEIIEHKAWSGNDRDKTAHFNTEIYLKGNTRNICVKAWEC
TGLAWEWWRQVIDAQNIPLVKERTFSIWGTTLYPKKSVEPEI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
slo YP_281505.1 streptolysin O Virulence Not named Protein 8e-127 55
hly AAA69525.1 listeriolysin O Virulence LIPI-1 Protein 7e-117 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CLL_A2808 YP_001886995.1 tetanolysin O VFG2275 Protein 4e-138 61
CLL_A2808 YP_001886995.1 tetanolysin O VFG0976 Protein 2e-127 56
CLL_A2808 YP_001886995.1 tetanolysin O VFG0074 Protein 3e-117 49
CLL_A2808 YP_001886995.1 tetanolysin O VFG1363 Protein 4e-106 46