Gene Information

Name : CLL_A0207 (CLL_A0207)
Accession : YP_001884443.1
Strain : Clostridium botulinum Eklund 17B
Genome accession: NC_010674
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence ClpC/mecB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 215746 - 218190 bp
Length : 2445 bp
Strand : +
Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728

DNA sequence :
TTGAGTATGGATTTCAATAAATTTACAGAAAGAACTCAATCAATAATATTAGAAGCACAAATTGAATCACAAGAGTTTAA
ACATGGATATGTAGGTACAGAACATTTATTATTGGGTTTAGTAAAAGAAAAAGGCCAGCAATCCAATATATTAAACGAAT
TTGGTATTGATGCTGAAATAGTAAGAGATATGATAAGTAGATATTTAGGCTATGGTGAATTACAAATGCCTGAAGATGAT
ATATTATTAACACCTAGAGCAAAAAAACTTCTTGATGAAAGCTTTATGGAGGCTAAAAAATTTAGTCATAAAAATGTTAG
TCCAGAACATATATTAATGGCATTGCTTAATCAAGAAGAAGGAATGGCGTATACTATATTAAAAAATTTAAAATTAAATT
TTAAGGAGATAAAAGATAAATTATTTATATTTTTAAATGGTCAGTATTCAGATGAAAATGAAGAAATTAAATCTCCAAGA
TCAGAAAAAACTAAAACTCCTATGTTAGATAAATACGGAAGAGATCTAACACAATTTGCAAGAGATGGTGGATTAGATCC
TGTGATTGGAAGAGATTTAGAAAATCAAAGAGTTTTAGAAATATTATGTAGAAGGATAAAAAACAATCCTTGTTTAATAG
GTGAACCTGGAGTTGGAAAGACAGCAGTAATTGAGGGGTTAGCACAAAGGATTGTAGAAGGTAATATTCCTGAAATACTA
AGAGGTAAGAGAATTGTTTCACTTGATTTGACTGCATTACTTGCAGGTGCTAAATATAGAGGTGAATTTGAAGATAGATT
AAAAAAGGTAATGCTAGAAATAGAAAAAGATAAAAGCATTATAATATTCATAGATGAAATTCATACAATAATAGGTGCAG
GAGCAGCTGAAGGTGCAATAGATGCTTCAAATATATTAAAACCAGCACTTTCTAGAGGCGAAATTCAATGTATAGGTGCA
ACAACTATAAACGAATATAGAAAACATATAGAAAAAGATTCTGCTTTAGAAAGAAGATTTCAACCTGTTAATGTTGGTGA
GCCATCAAAAGATGAAACACTAATAATATTAAGAGGATTAAGAGAAAAGTATGAAGAACATCACAATGTTAACATTACAG
ATAAAGCATTAGAAGCTGCTGTTGAGTTATCTGATAGATATATTACAGATAGATTTATGCCAGACAAAGCTATTGATTTG
ATTGATGAGGCATGTGCTAAAGTTAGAATAAAAAATCTAATTCCACCTGCTAATTTAAAATCAATGGAAGATGAAATAAA
AGAAACAACTAAAGAAAAAGAAGAATGTATTAGGGTCCAAGATTTTGAAAAAGCGGCAAATATGAGAGATATTGAAAATG
ATTTAAAAGAAGAATTAGAAGCACTTAGAAAAGAGTGGAGTGATAAAAATTCTAATAAGCAATTAAATGTAGATGAAGAA
GATATAGCAGAAGTTGTATCATCTTGGACTAAAATACCTGCTAAAAAACTTACAGAAAAAGAAAGTGAAAAATTACTAAA
ACTTGAAAATATATTACAAAAAAGAGTTATAGGTCAAACTGAAGCTGTTGAATCTATAGCTAAGGCAGTAAGAAGAGCTA
GAGTGGGAATAAAAGATCCTAATAGACCAATCGGAACGTTTATATTTTTAGGACCTACAGGTGTTGGTAAAACAGAACTT
TCAAAAGCATTAGCTGAAACTATGTTTGGAGATGAAAATAGCATAATAAGAATAGATATGTCTGAATACATGGAAAGCAA
CTCAGTTTCTAAATTAATAGGTTCACCTCCAGGATATGTAGGATATGATGATGGAGGTCAATTAACAGAAGCAGTGAGGA
GAAAGCCTTATTCAGTAGTACTTCTAGATGAAATTGAAAAAGCTCATCAAGATGTATTTAATATATTACTTCAAATTATG
GAAGATGGGAGACTTACAGATTCCCATGGAAAAGTAGTTAATTTTAAAAATACAATAGTTATAATGACTTCTAATGTAGG
AGCACATCAAATAAAAAAACAAAAAACAATTGGATTTAATACAAGTATTGATGAAAATTCAGAATATGAAAAGATGAAAG
ATAATGTTTTAGAAGAATTAAAGAGAAGCTTTAAACCAGAATTCTTAAATAGAATAGACGATACAATAGTATTCCATAAA
TTAAAAGAAGATGATCTTTTAGATATAGTTGATTTAATGTTAAAATCTATTACTAAAAGACTTGAAAATAAAGATATACA
CTTAAACTTTGAAAAAGATAGTAAAAAATTCTTAATTAATAAAAGAATTGATTTAAATTATGGAGCAAGACCATTAAGAA
GAATTATTACTAAAGAAGTAGAAGATAAATTAAGTGAAGAGATACTTTTAGGTAATATAAAAATTGGAGATAGAATTAAA
GTAAATGAATCAAAAGATAATTTAGTTTTTACAAAACTAGATTAA

Protein sequence :
MSMDFNKFTERTQSIILEAQIESQEFKHGYVGTEHLLLGLVKEKGQQSNILNEFGIDAEIVRDMISRYLGYGELQMPEDD
ILLTPRAKKLLDESFMEAKKFSHKNVSPEHILMALLNQEEGMAYTILKNLKLNFKEIKDKLFIFLNGQYSDENEEIKSPR
SEKTKTPMLDKYGRDLTQFARDGGLDPVIGRDLENQRVLEILCRRIKNNPCLIGEPGVGKTAVIEGLAQRIVEGNIPEIL
RGKRIVSLDLTALLAGAKYRGEFEDRLKKVMLEIEKDKSIIIFIDEIHTIIGAGAAEGAIDASNILKPALSRGEIQCIGA
TTINEYRKHIEKDSALERRFQPVNVGEPSKDETLIILRGLREKYEEHHNVNITDKALEAAVELSDRYITDRFMPDKAIDL
IDEACAKVRIKNLIPPANLKSMEDEIKETTKEKEECIRVQDFEKAANMRDIENDLKEELEALRKEWSDKNSNKQLNVDEE
DIAEVVSSWTKIPAKKLTEKESEKLLKLENILQKRVIGQTEAVESIAKAVRRARVGIKDPNRPIGTFIFLGPTGVGKTEL
SKALAETMFGDENSIIRIDMSEYMESNSVSKLIGSPPGYVGYDDGGQLTEAVRRKPYSVVLLDEIEKAHQDVFNILLQIM
EDGRLTDSHGKVVNFKNTIVIMTSNVGAHQIKKQKTIGFNTSIDENSEYEKMKDNVLEELKRSFKPEFLNRIDDTIVFHK
LKEDDLLDIVDLMLKSITKRLENKDIHLNFEKDSKKFLINKRIDLNYGARPLRRIITKEVEDKLSEEILLGNIKIGDRIK
VNESKDNLVFTKLD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CLL_A0207 YP_001884443.1 negative regulator of genetic competence ClpC/mecB VFG0079 Protein 0.0 56
CLL_A0207 YP_001884443.1 negative regulator of genetic competence ClpC/mecB VFG0080 Protein 9e-134 50