Gene Information

Name : panE (CLL_A1138)
Accession : YP_001885336.1
Strain : Clostridium botulinum Eklund 17B
Genome accession: NC_010674
Putative virulence/resistance : Unknown
Product : 2-dehydropantoate 2-reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG1893
EC number : 1.1.1.169
Position : 1168349 - 1169278 bp
Length : 930 bp
Strand : +
Note : ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis

DNA sequence :
ATGAAAATTGCAATTGTTGGAGCAGGAGCTATGGGCTCACGTTATGGATATATGTTACATGAATCTGGAAATGAAGTTTT
CTTGATAGATGCTTGGAAGGATCATGTAGATACTATAAATAAAGACGGATTAACAGTTGAAGAAAATGGAGAATGTAAGA
AGGTAAAAATACCAGCAATGTTACCAGAAGATGCTAAAGAAGTTCCGGATTTAGTGATTTTATTTACTAAATCAATGGGA
TTAGAATCTATGCTAAAATCTGTAAAGAATATTTTAGGAAAACATACAAGAGTATTATGCCTATTAAATGGATTAGGTCA
TAATGAAACTATTGAAAAATATGTTGATAGTAAAAATATACTTATGGGTGTAACTTTATGGACAGCTGGATTAGCAGGTC
CTGGACATGTTGTATTAACTGGAGATGGAAGCTTAGAAGTACAAAATATTGATTCTAATATGGAAGTAGAAGCAAGAGAG
ATTTGTGACATATTAAATCAAGCAGGATTAAAAGCTCACTATAGTGAAAATGTTATATTTTCAATATGGCGTAAAGCATG
TGTAAATGGAACTTTAAATAGTTGTTGCACAATTTTAGATTGTAATATTAAAGAGTTTGGAGAGCTAAAAGAAACTCCAG
AGCTTATTCGTAATATTATAAAAGAATTCGCTGATATTGCTGCTAAATATGGAGTAGAATTAAATGTTGAAGAGGTTGCA
AAAGGAATAGAAAAAATATATGATCCAAGCCAAGCTGGAGAACACTATCCATCAATGCATCAAGATTTAATTCAAAATCA
TCGTCTTACAGAAATTGATTATATAAACGGATATGTATCTAGAAAAGGTAAAGAATTTAATATAAAGACAGAATGTAATG
ATTTATTAACAACTATGGTTCATGCAAAAGAACAATTACTTGTTAAATAA

Protein sequence :
MKIAIVGAGAMGSRYGYMLHESGNEVFLIDAWKDHVDTINKDGLTVEENGECKKVKIPAMLPEDAKEVPDLVILFTKSMG
LESMLKSVKNILGKHTRVLCLLNGLGHNETIEKYVDSKNILMGVTLWTAGLAGPGHVVLTGDGSLEVQNIDSNMEVEARE
ICDILNQAGLKAHYSENVIFSIWRKACVNGTLNSCCTILDCNIKEFGELKETPELIRNIIKEFADIAAKYGVELNVEEVA
KGIEKIYDPSQAGEHYPSMHQDLIQNHRLTEIDYINGYVSRKGKEFNIKTECNDLLTTMVHAKEQLLVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF0517 NP_814296.1 2-dehydropantoate 2-reductase Not tested Not named Protein 1e-75 51
ef0037 AAM75243.1 EF0037 Not tested Not named Protein 1e-75 51