Gene Information

Name : BH0348 (BH0348)
Accession : YP_001883781.1
Strain : Borrelia hermsii DAH
Genome accession: NC_010673
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 360376 - 361809 bp
Length : 1434 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGATACAAAAATTAACAAAAATAGTAGCAACAATATCTGACCTCAGATGTGATCCAGAACATATAAAAGAGTTATATGA
AGCAGGGGTAAATGTAATAAGACTTAACACTGCACATCAATCTCATGACGATGCAATAAAAGTAATAAACAATGTTAGGC
AAGTTTCAAATAAAATAGCATTAATGATTGATACAAAAGGACCAGAAGTTAGAACAGCCAATATTGAAAATCCCATTACT
GTGAAGATAGGAGACAAAATAATAATCTCAACATCACCTATCAATGAATCTAATTCATTGCAAACCAACTATGAGGGCTT
TGTAAATGAAGTTCCAAATGGATCAAAAATCCTTATTGATGATGGCGAACTTGAAATGATTGTCATCGAAAAACTCGCAG
ACAGATTAATCTGTGAAGTTAAAAATGATGGTCATATCAAAAACAAAAAATCAATCAATACACCAGGAATTCCACTTAAA
CTACAATCTGTCACTGAAAAGGATAAGGGATTTATTGAACTTGCCGCAAAACAAAATATTGATTTTATTGCCCACTCATT
TGTAAGACATGCAAAAGACATTCAAGACGTTAAAGATATATTAAATACTGCTGGAAATCCAGATGTCAAAATTATTGCCA
AGGTTGAAAATCAAGAAGGAATTGATAATATTGAAGAGATTGCAAAGGCTTCTTATGGGATTATGGTTGCAAGGGGCGAT
ATGGGAGTCGAAATACCTGCTGAAGATGTTCCTTTGGCACAAATTAAAATAACAAAAACCTGCATTAAATATGGAATACC
CGTAATTACCGCAACACAAATGCTGCACACAATGATTGAAAATCCAAGACCTACAAGAGCAGAGGTTTCCGATGTTGCTA
ATGCAATTCTAAATGGCACAGATGCCATAATGTTATCTGGTGAGACAGCTTATGGCAAATACCCACTCGAAGCTGTTAAG
ATGATGACTAAAATTGCTATAGAGGTTGAAAAATATAGAGAAAAAACACTATTTAAAGATGAAATTTTCTGCAGCAAAAA
GATCATAAGAAACTATATTATTAAATGTGCAATTGATGCAACCAAGATAATGCCTGTTAAAGCTATTATTGTTGATTCAC
TTAAGGGAAGAACCGCAAGAATAATGGCAACATACAGAGCAAGTGTACCTCTATTTATTACAACAAATAATGAAAGGATA
GCAAGGGAATTATCACTTTCTTACGGTGTTTATTCTAATCTTGTCGATCATAACTTCAAGGGAACAACTGAATTCGTAGT
AACTTCTCTTGAAATGCTGAAAACACAAGGCATAGTTAAAGATTCAGATATTGTAGTAATTATCTCTGGAAATCCAAACA
GAGCTACCAACAAAGGTACAGAATTTATGGAAATAAATACAGTAGAAGACGCAATTAAGGAACGAAACCTATAA

Protein sequence :
MIQKLTKIVATISDLRCDPEHIKELYEAGVNVIRLNTAHQSHDDAIKVINNVRQVSNKIALMIDTKGPEVRTANIENPIT
VKIGDKIIISTSPINESNSLQTNYEGFVNEVPNGSKILIDDGELEMIVIEKLADRLICEVKNDGHIKNKKSINTPGIPLK
LQSVTEKDKGFIELAAKQNIDFIAHSFVRHAKDIQDVKDILNTAGNPDVKIIAKVENQEGIDNIEEIAKASYGIMVARGD
MGVEIPAEDVPLAQIKITKTCIKYGIPVITATQMLHTMIENPRPTRAEVSDVANAILNGTDAIMLSGETAYGKYPLEAVK
MMTKIAIEVEKYREKTLFKDEIFCSKKIIRNYIIKCAIDATKIMPVKAIIVDSLKGRTARIMATYRASVPLFITTNNERI
ARELSLSYGVYSNLVDHNFKGTTEFVVTSLEMLKTQGIVKDSDIVVIISGNPNRATNKGTEFMEINTVEDAIKERNL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-68 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 7e-69 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 7e-69 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-68 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BH0348 YP_001883781.1 pyruvate kinase VFG0479 Protein 3e-69 41