Gene Information

Name : BH0288 (BH0288)
Accession : YP_001883725.1
Strain : Borrelia hermsii DAH
Genome accession: NC_010673
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 300155 - 301465 bp
Length : 1311 bp
Strand : -
Note : -

DNA sequence :
TTGATGGACAACTTTTTTGAGGGTTATTCAAAAATATTGGATGGTGTTGAGACTATATCTCTTGTTGGCAGAGTAAGAAA
GATCAAGGGACTTTTAATAGAGAGTGTGGGTCCAAAATGTGGTATTGGTGATTTATGTTTCATCCAGCAGGTAAGTGGTA
AGAAAATATATGCTGAAGTTTTAGGTTTTAATGGATGTTTTGTTAGCCTTATGGCTTATGAAGGATTTGATGGAATTGAG
GTTGGCGATAAAGTTTATTCCTTAAATAAAAAGCCTCAAATTAATCTTAGCGATGAATTGCTAGGAAGGGTAATTGATTC
TCTTGGTAGGCCTATTGATAATAAGGGTCAGTTTCTTGGCAATCATTATAAGGAATTAAGTTTTAGTAGTATTAATCCTT
TAAAAAGAGGTATTTTTTCTAAGCAAATAGTTACTGGGGTTAGAGTTCTTGATGGGTTTTTACCAGTTGCAAAGGGGCAA
CGTGTGGGTATTTTCTCAGGAGCTGGTGTTGGTAAATCTACTTTGCTTGGTATGATTGCTAAAAATTCTAAGGCAGATGT
TAATGTTATTGCATTTATTGGCGAGAGAGGCCGTGAGCTTAATGAGTTTATCGAGTATGATCTTGGAGAAGAATGCTTTA
AGAAAAGTGTTTTGATTGTGTCGACTTCTGATGAATCTCCTATTTCAAGATATAAAGGTGCTTATACTGCAACATTAATA
GCTGAACACTTTAGAGATCGTGGTATGGATGTTATGTTGCTATTTGATTCAATTACGAGATTTGCAAATGCTAAAAGGGA
AATTAGCCTTTCTATGGGAGAGCTGCCTGCTACTAAAGGATATCCTCCTTCTGTTTTTGTAGAAATTCCTATTTTGCTTG
AGCGTTTGGGACTTAATGGTAAGGGCAGTATTACAGGGTTTTATACTGTGCTTGTTGAGAGTGATGATTTTACAGAACCA
ATAGCTGATAATATGAAAGCTGTTTTGGATGGACATATTATTTTGGATAGAGATTTATCTGATAGAGGTATTTATCCTTC
GGTAAATATTTTAAGTTCAACATCAAGATCTCTGCATAGAATAGTAAATTTTGAAAAACAGAAATTAATATCTAAAATTA
GGAATTTGTTATCAATTTATAAAAATTATGAAGATTTAATTAAGACGGGAATTTATATGAAAGGTTCTAATAAGGAAGTT
GATTTGGCAATTGCAAAATATCCAAAAATTATTGATTTTTTGTCTCAAGGGATGCAAGAAGAATTTGATTTTGAAAATTT
GGATAATGAAATGAGAGAGATATTAGCTTGA

Protein sequence :
MMDNFFEGYSKILDGVETISLVGRVRKIKGLLIESVGPKCGIGDLCFIQQVSGKKIYAEVLGFNGCFVSLMAYEGFDGIE
VGDKVYSLNKKPQINLSDELLGRVIDSLGRPIDNKGQFLGNHYKELSFSSINPLKRGIFSKQIVTGVRVLDGFLPVAKGQ
RVGIFSGAGVGKSTLLGMIAKNSKADVNVIAFIGERGRELNEFIEYDLGEECFKKSVLIVSTSDESPISRYKGAYTATLI
AEHFRDRGMDVMLLFDSITRFANAKREISLSMGELPATKGYPPSVFVEIPILLERLGLNGKGSITGFYTVLVESDDFTEP
IADNMKAVLDGHIILDRDLSDRGIYPSVNILSSTSRSLHRIVNFEKQKLISKIRNLLSIYKNYEDLIKTGIYMKGSNKEV
DLAIAKYPKIIDFLSQGMQEEFDFENLDNEMREILA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 6e-78 44
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 5e-80 42
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 2e-79 42
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-79 42
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 7e-80 42
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-80 42
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-84 42
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-84 42
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 7e-83 42
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 7e-83 42
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-83 42
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 4e-79 42
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-82 42
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 4e-83 42
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-81 42
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-83 42
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 3e-66 41
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-67 41
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-67 41
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 6e-70 41
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 3e-70 41
escN AAC31513.1 L0034 Virulence LEE Protein 2e-68 41
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-68 41
escN AAC38383.1 EscN Virulence LEE Protein 2e-68 41
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-68 41
escN YP_003236088.1 translocator EscN Virulence LEE Protein 6e-68 41
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-68 41
escN NP_290268.1 hypothetical protein Virulence LEE Protein 3e-68 41
ECs4568 NP_312595.1 EscN Virulence LEE Protein 3e-68 41
escN AAK26715.1 EscN Virulence LEE Protein 3e-68 41
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-68 41
escN AAL57542.1 EscN Virulence LEE Protein 3e-68 41
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 1e-68 41
unnamed AAL06369.1 EscN Virulence LEE Protein 7e-68 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BH0288 YP_001883725.1 flagellum-specific ATP synthase VFG2144 Protein 3e-90 46
BH0288 YP_001883725.1 flagellum-specific ATP synthase VFG2499 Protein 8e-79 45
BH0288 YP_001883725.1 flagellum-specific ATP synthase VFG0390 Protein 1e-82 44
BH0288 YP_001883725.1 flagellum-specific ATP synthase VFG2331 Protein 3e-74 44
BH0288 YP_001883725.1 flagellum-specific ATP synthase VFG1254 Protein 2e-85 43
BH0288 YP_001883725.1 flagellum-specific ATP synthase VFG0048 Protein 1e-81 43
BH0288 YP_001883725.1 flagellum-specific ATP synthase VFG0515 Protein 3e-80 42
BH0288 YP_001883725.1 flagellum-specific ATP synthase VFG0192 Protein 2e-82 41
BH0288 YP_001883725.1 flagellum-specific ATP synthase VFG0730 Protein 1e-68 41
BH0288 YP_001883725.1 flagellum-specific ATP synthase VFG0812 Protein 1e-68 41