Gene Information

Name : leuS (BH0251)
Accession : YP_001883687.1
Strain : Borrelia hermsii DAH
Genome accession: NC_010673
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 258405 - 260933 bp
Length : 2529 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGTCTGAATATAATTTCACTAAGATAGAAAAAAAATGGCAGGATTATTGGGATAAACACAAAACATACAAAGTTAATGA
AGATCCAAATATTCCTAAAGAAAAACGAATTTACATTCTTGATATGTTTCCCTACCCTTCAGCTAATGGACTCCATGTTG
GGCATCCTGAAGGTTATACAGCAACTGACATATTAACAAGATATAAACTCTTAAATGGATTTAATGTACTTCACCCAATA
GGATTTGATAGTTTTGGATTGCCTGCAGAAAATTACGCAATACAAACAGGAGAGCATCCAAAAAAAATAACAGAAAAAAA
TATTAAAAAATTTAAAGAACAAATTAAAGCATTAGGATTTGCCTATGATTGGGATAGAGAAATCAGAACCCACGATGAAA
ATTACTACAAATGGACACAATGGATTTTCCTAAAATTATATAAAAAAGGTTTAGCTTACACAAAAGAAATGCCCGTATGG
TACTGCCCTGACCTTGGAACAGTACTCTCAAATGAAGAAGTGATACAAACACCTGATGGACCTAGATCTGAGCGGGGATT
TCACAAAGTAAAAAGAAAACCTTTAAGACAATGGATACTCAAAATCACAGAATATGCAGAAAGACTAATTAAAGATCTCG
AAGAGATAGATTGGCCTGAATCTGTTAAAGAAATGCAAAAAAATTGGATTGGAAAGTCAACAGGCGCCGAGATCGAATTT
TCAGTAAAGGCAAGTAAAGAAAAGATAAAAGTGTTTACAACAAGACCAGACACAATTTTTGGAGTAACATATTTAGTGCT
TGCACCAGAGCATAGCATAGTAGATAAAATTACAAAAGATGAATTTAAACCTATGATCGTAGAGTATAGAGAAAGAGAAA
CTCTTAAAAGCGATCTTGAAAGAACTTCTCTTGAAAAAGATAAAACGGGAGTATTTACAGGCGCATATGCTATTAATCCA
ATAACTGGAGAAGAAATACCAATCTGGATAGGCAGCTATATACTTGGAACCTACGGCACTGGAGCTGTAATGAGTGTCCC
AGCACATGATGCTAGAGATTTTGAATTTGCAAAAAAATATAATCTACCAATCAAACAAGTAGTCTCTCAAACAGGAAACA
ATGAAATACTAACACAACCATTTACTGAAAATGGCATTTCAATTAATACCCCTGAAGAATTTAATAATCTTAAAACTGAT
GAAATCAAAGAAAGAGTAATTAAATGGCTTACTGAAAACAAGAAGGGTCAAAAAAAGGTTAATTATAAACTTAGAGATTG
GATTTTTTCAAGACAAAGATATTGGGGAGAACCCATTCCTATTATACTTGATGATGATTTAAATGAAATACCACTAGAAG
AAGATGAATTACCTCTAAGGCTTCCAGAAATAGAAAATTATAAACCATCAGGTACAGGCGAATCTCCTCTATCAAGAATC
CAAGATTGGGTCAATATTAAACGTAATGGAAAAACATATAAAAGAGAAACGAACACAATGCCTCAATGGGCAGGTTCCTG
CTGGTATTACATACGTTACCTTGATCCAAATAATGACAATGAATTTGCAAGTAAAGAAAAAATTAATTACTGGATGCCAG
TTGATCTTTATATTGGAGGTGCTGAGCACTCGGTATTACACTTACTATATGCAAGATTTTGGCATAAAGTTCTTTATGAT
TTAGGATATGTCAATACAAAAGAACCCTTTAAAAAACTAATAAATCAGGGAATGATAACATCATTTGCATATCAAGACGA
AAATGGTATTTTAATTCCCAATGACGAGGTTGAAAAGAAAGATAATAAGTTTTTTTCCAAAAAAAATAATAAGGAACTCA
AACAAATAGTTGCAAAAATGTCAAAATCACTCAAAAATATAATAAATCCAGACGATATTATTAAAGAATACGGTGCAGAT
TCAATGAGAATCTACGAAATGTTCATGGGCCCTTTAACTGATTCAAAACCTTGGAATACACAAGGACTAATTGGAATTTT
TAGATTCTTAAACAAAATATGGACTATTAAGAACAAAGAACTAACAAAAGAATCAGCATCAAAAGAAATAATATCTGAAC
TTCACAAAACAATCAAAAAAGTAACAGAAGACATAGAAAATTTAAATTTTAATACTGCAATTTCATCATTGATGATATTT
ATAAATGAACTTTTAAAACATGATAAAAATTACTTAGAAATCTTCAAGCCTCTAACCATTATCCTTTCACCATTTGCGCC
TCATCTAGGAGAAGAATTATGGGAATATATGGGAGAAACCCCCAGCATATTCAAAAGTGCAAAGTGGCCAGAATACGATC
CAAATCTAATTATTGATAATACAAGAGAGATTGTACTGCAAATTAATGGCAAAATAAAAGATAAAATTATCTTAAACAAA
GGCACAAATGAGGAAGCTCTTAAAAGTATTGCACTTAAAAATCACAAAATCATGCAAAATATACAAAATAAACAAATAAT
AAAGATCATTACGGTCAAAGATAAGCTTATAAATATAGTAACAAGATAA

Protein sequence :
MSEYNFTKIEKKWQDYWDKHKTYKVNEDPNIPKEKRIYILDMFPYPSANGLHVGHPEGYTATDILTRYKLLNGFNVLHPI
GFDSFGLPAENYAIQTGEHPKKITEKNIKKFKEQIKALGFAYDWDREIRTHDENYYKWTQWIFLKLYKKGLAYTKEMPVW
YCPDLGTVLSNEEVIQTPDGPRSERGFHKVKRKPLRQWILKITEYAERLIKDLEEIDWPESVKEMQKNWIGKSTGAEIEF
SVKASKEKIKVFTTRPDTIFGVTYLVLAPEHSIVDKITKDEFKPMIVEYRERETLKSDLERTSLEKDKTGVFTGAYAINP
ITGEEIPIWIGSYILGTYGTGAVMSVPAHDARDFEFAKKYNLPIKQVVSQTGNNEILTQPFTENGISINTPEEFNNLKTD
EIKERVIKWLTENKKGQKKVNYKLRDWIFSRQRYWGEPIPIILDDDLNEIPLEEDELPLRLPEIENYKPSGTGESPLSRI
QDWVNIKRNGKTYKRETNTMPQWAGSCWYYIRYLDPNNDNEFASKEKINYWMPVDLYIGGAEHSVLHLLYARFWHKVLYD
LGYVNTKEPFKKLINQGMITSFAYQDENGILIPNDEVEKKDNKFFSKKNNKELKQIVAKMSKSLKNIINPDDIIKEYGAD
SMRIYEMFMGPLTDSKPWNTQGLIGIFRFLNKIWTIKNKELTKESASKEIISELHKTIKKVTEDIENLNFNTAISSLMIF
INELLKHDKNYLEIFKPLTIILSPFAPHLGEELWEYMGETPSIFKSAKWPEYDPNLIIDNTREIVLQINGKIKDKIILNK
GTNEEALKSIALKNHKIMQNIQNKQIIKIITVKDKLINIVTR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 54