Gene Information

Name : iucA (SbBS512_E4634)
Accession : YP_001882801.1
Strain : Shigella boydii CDC 3083-94
Genome accession: NC_010658
Putative virulence/resistance : Virulence
Product : aerobactin synthase subunit IucA
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG4264
EC number : 6.3.2.27
Position : 4330325 - 4332049 bp
Length : 1725 bp
Strand : -
Note : identified by similarity to SP:Q47316; match to protein family HMM PF04183

DNA sequence :
ATGACCCTGCCCTCTGAAAAACCAGCCACAGATGTGGCTGCGCAGTGCTTCCTGAATGCACTGATTCGTGAAACCACAGA
CTGGAAACTGACAGAATACCCGCCAGACGAATTGCTCATCCCGCTGGATGAGCAGAAATCGCTCCATTTCAGAGTGACTT
ATTTCTCCCCAACCCAGCATCACCGCTTTGCATTTCCTGCACGTCTGGTCACGGCATCAGGCAGTTATCCTGTCGACTTT
ACCACTCTCTCCCGGCTTATTATTGATAAGCTACGCCATCAACTGTTTCTGCCCGTTCCCCTCTGCGAAACTTTCCACCA
GCGCGTGCTGGAAAGCCATGTCCATACGCAACAGGCAATTGATGCCCGTCATGACTGGGCCGCTCTGCGTGAAAAAGCGT
TGAATTTTGGCGAGGCTGAGCAGGCGCTGCTGACAGGACACGCTTTCCACCCTGCGCCTAAGTCTCATGAACCGTTTAAC
CGGCGGGAGGCTGAACGCTACCTGCCTGATATGGCACCCCACTTCCCACTGCGGTGGTTTTCGGTGGATAAAACACAAAT
CGCCGGTGAAAGTTTGCATCTCAACCTTCAACAGCGGCTGACGCGATTTGCCGCAGAGAATGCGCCTCAGTTACTCAACG
AATTAAGTGACAACCAATGGCTGTTCCCGTTGCACCCGTGGCAGGGGGAATATCTTTTGCAGCAGGGGTGGTGCCAGGCA
CTTGTTGCTAAAGGGCTGATTAAAGACTTAGGTGAGGCCGGCACGTCGTGGCTGCCGACCACCTCTTCCCGTTCCCTCTA
CTGTGCCACCAGCCGCGATATGATCAAGTTCTCCCTGAGCGTACGGCTGACCAACTCCATCCGTACTCTGTCCGTGAAAG
AAGTGAAGCGTGGGATGCGCCTGGCACGCCTGGCTCAAACCGACGGCTGGCAGATGCTACAGGTCCGCTTCCCGACTTTC
CGGGTAATGCAGGAGGATGGCTGGGCCGGGCTGCTCGATCTTAACGGCAACATCATGCAGGAAAGTCTGTTTGCCCTGCG
TGAAAATCTGCTGGTGGATCAGCCGAAAAGCCAGACTAACGTACTGGTCTCCCTGACTCAGGCCGCACCTGATGGCGGTG
ATTCGCTGCTGGTTTCGGCGGTAAAACGCCTGAGCGATCGCCTCGGTATCACTGTGCAACAGGCCGCCCATGCATGGGTC
GATGCATACTGTCAGCAAGTGCTAAAGCCGCTGTTTACGGCTGAAGCGGATTACGGCCTGGTGCTGCTGGCGCATCAGCA
AAATATTCTTGTCCAGATGCTTGGGGATCTGCCGGTCGGATTTATTTACCGTGACTGTCAGGGCAGCGCTTTTATGCCTC
ACGCGACAGACTGGCTCGATTCTATTGGCGAGGCGCAGGCGGAAAATATTTTCACCCATGAGCAGTTGCTGCGCTATTTC
CCTTATTACCTGCTGGTTAACTCCACTTTTGCTGTGACCGCTGCGCTGGGGGCTGCCGGGCTGGACAGCGAATCGAATCT
GATGGCTCGTGTACGAGCATCGCTGGCTGAAGTGCGTGATCAGGTGACTCATAAAACCTGTCTCAACTACGTGCTGGAAA
GTCCGTACTGGAACGTAAAAGGTAACTTTTTCTGTTATCTGAACGATCATAACGAGAACACCATTGTTGATCCTTCGGTG
ATCTATTTCGATTTCGCTAACCCGCTGCAGGCTCAGGAGGTCTGA

Protein sequence :
MTLPSEKPATDVAAQCFLNALIRETTDWKLTEYPPDELLIPLDEQKSLHFRVTYFSPTQHHRFAFPARLVTASGSYPVDF
TTLSRLIIDKLRHQLFLPVPLCETFHQRVLESHVHTQQAIDARHDWAALREKALNFGEAEQALLTGHAFHPAPKSHEPFN
RREAERYLPDMAPHFPLRWFSVDKTQIAGESLHLNLQQRLTRFAAENAPQLLNELSDNQWLFPLHPWQGEYLLQQGWCQA
LVAKGLIKDLGEAGTSWLPTTSSRSLYCATSRDMIKFSLSVRLTNSIRTLSVKEVKRGMRLARLAQTDGWQMLQVRFPTF
RVMQEDGWAGLLDLNGNIMQESLFALRENLLVDQPKSQTNVLVSLTQAAPDGGDSLLVSAVKRLSDRLGITVQQAAHAWV
DAYCQQVLKPLFTAEADYGLVLLAHQQNILVQMLGDLPVGFIYRDCQGSAFMPHATDWLDSIGEAQAENIFTHEQLLRYF
PYYLLVNSTFAVTAALGAAGLDSESNLMARVRASLAEVRDQVTHKTCLNYVLESPYWNVKGNFFCYLNDHNENTIVDPSV
IYFDFANPLQAQEV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iucA AAD44746.1 IucA Virulence SHI-2 Protein 0.0 99
iucA NP_839223.1 siderophore biosynthesis protein Virulence SHI-2 Protein 0.0 99
iucA NP_709454.2 siderophore biosynthesis protein Virulence SHI-2 Protein 0.0 99
iucA YP_002414046.1 aerobactin siderophore biosynthesis protein Virulence Not named Protein 0.0 99
iucA AAK71631.1 IucA Virulence SHI-3 Protein 0.0 94

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
iucA YP_001882801.1 aerobactin synthase subunit IucA VFG0615 Protein 0.0 99
iucA YP_001882801.1 aerobactin synthase subunit IucA VFG0940 Protein 0.0 99
iucA YP_001882801.1 aerobactin synthase subunit IucA VFG1081 Protein 0.0 94