Gene Information

Name : iucC (SbBS512_E4632)
Accession : YP_001882799.1
Strain : Shigella boydii CDC 3083-94
Genome accession: NC_010658
Putative virulence/resistance : Virulence
Product : aerobactin synthase subunit IucC
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG4264
EC number : 6.3.2.27
Position : 4327635 - 4329377 bp
Length : 1743 bp
Strand : -
Note : identified by similarity to SP:Q47318; match to protein family HMM PF04183

DNA sequence :
ATGAATCACAAGGACTGGGATTTTGTTAACCGTCGGCTGGTGGCAAAAATGTTGTCTGAGATGGAGTATGAGCAGGTTTT
CCACGCGGAATCTCAGGGCGATGACCACTACTGCATTAACCTGCCGGGAGCACAATGGCGCTTCATCGCTGAACGTGGTA
TCTGGGGCTGGCTGTGGATTGATGCCCAAACGTTGCGCTGCACGGACGAACCAGTACTGGCGCAGACGCTGCTGATGCAG
CTAAAGCCGGTGCTGTCAATGAGTGATGCCACTGTTGCAGAGCATATGCAGGATTTGTATGCCACGCTACTGGGCGACCT
GCAACTGCTGAAGGCCCGTCGCGGACTGAGTGCCAGTGACCTGATTAATCTTGATGCCGATCGTCTGCAATGCCTGCTGA
GCGGTCATCCTAAATTCGTTTTTAATAAAGGTCGCCGTGGCTGGGGCAAAGAGGCGCTGGAACGATATGCGCCAGAGTAT
ACCAACACCTTCAGACTGCACTGGCTGGCGGTAAAACGTGAACATATGATCTGGCGCTGCGATAACGATCTGGATATTCA
GCAGTTGTTGACTGCCGCAATGGATCCGCAGGAGTTTACACGCTTCAGTCAGGTCTGGCAGGAAAACGGGCTGGATCACA
ACTGGCTACCGCTGCCGGTACATCCGTGGCAGTGGCAGCAAAAAATCGCCACAGACTTCATCGCTGATTTTGTCGAAGGC
AGGATGGTGTCTCTCGGCGAGTTTGGCGACCAGTGGCTCGCCCAGCAGTCGCTGCGTACCCTGACCAACGCCAGCCGCCG
GGGAGGGCTGGATATCAAGCTGCCGCTGACCATCTACAACACCTCATGCTACCGGGGGATCCCTGGCAGATATATCGCTG
CCGGACCACTGGCTTCACGCTGGCTGCAACAGGTTTTTGCGACCGACGCCACCCTGGTGCAAAGCGGCGCAGTGATCCTT
GGTGAACCGGCGGCAGGCTATGTGTCCCATGAAGGCTATGCCGCGCTTGCCCGGGCTCCCTATCGCTACCAGGAAATGCT
TGGTGTTATCTGGCGGGAGAATCCGTGCCGCTGGCTGAAACCGGATGAAAGTCCTGTTCTGATGGCAACACTGATGGAGT
GCGACGAAAACAATCAGCCGCTGGCAGGCGCATATATCGACCGCTCCGGACTGGACGCTGAAACCTGGCTTACGCAATTG
TTCCGGGTGGTTGTGGTTCCGCTGTATCACCTGCTTTGCCGCTACGGTGTCGCGCTTATTGCACACGGACAAAATATAAC
GCTCGCCATGAAAGAGGGGGTACCACAGCGTGTTCTGCTGAAAGACTTCCAGGGCGATATGCGGCTGGTGAAAGAAGCGT
TTCCCGAAATGGACTCTTTGCCTCAGGAGGTGCGTGATGCCACATCCCGTCTGAGTGCGGACTACTTAATCCATGATTTG
CAGACGGGTCACTTCGTGACAGTACTGCGTTTTATTTCGCCACTGATGGTTCGTCTTGGCGTACCTGAAAGGCGATTTTA
TCAACTGCTGGCAGCAGTGTTGAGTGATTACATGAACAAACATCCACAAATGGCAGAGCGTTTTGCGATTTTCTCACTCT
TCAGGCCACAAATCATTCGCGTGGTGCTGAACCCGGTAAAACTGACCTGGCCGGACCTGGATGGCGGCAGTCGCATGCTG
CCGAATTACCTTGAGAATCTGCAAAATCCGCTGTGGCTGGTAACTCAGGAATATGAATCATGA

Protein sequence :
MNHKDWDFVNRRLVAKMLSEMEYEQVFHAESQGDDHYCINLPGAQWRFIAERGIWGWLWIDAQTLRCTDEPVLAQTLLMQ
LKPVLSMSDATVAEHMQDLYATLLGDLQLLKARRGLSASDLINLDADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEY
TNTFRLHWLAVKREHMIWRCDNDLDIQQLLTAAMDPQEFTRFSQVWQENGLDHNWLPLPVHPWQWQQKIATDFIADFVEG
RMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASRWLQQVFATDATLVQSGAVIL
GEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLKPDESPVLMATLMECDENNQPLAGAYIDRSGLDAETWLTQL
FRVVVVPLYHLLCRYGVALIAHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEAFPEMDSLPQEVRDATSRLSADYLIHDL
QTGHFVTVLRFISPLMVRLGVPERRFYQLLAAVLSDYMNKHPQMAERFAIFSLFRPQIIRVVLNPVKLTWPDLDGGSRML
PNYLENLQNPLWLVTQEYES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iucC AAK71633.1 IucC Virulence SHI-3 Protein 0.0 99
iucC YP_002414044.1 Aerobactin siderophore biosynthesis protein Virulence Not named Protein 0.0 99
iucC NP_839221.1 siderophore biosynthesis protein Virulence SHI-2 Protein 0.0 99
iucC NP_709456.1 siderophore biosynthesis protein Virulence SHI-2 Protein 0.0 99
iucC AAD44748.1 IucC Virulence SHI-2 Protein 0.0 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
iucC YP_001882799.1 aerobactin synthase subunit IucC VFG0617 Protein 0.0 99
iucC YP_001882799.1 aerobactin synthase subunit IucC VFG1083 Protein 0.0 99
iucC YP_001882799.1 aerobactin synthase subunit IucC VFG0938 Protein 0.0 99