Gene Information

Name : ldcC1 (SbBS512_E0179)
Accession : YP_001878988.1
Strain : Shigella boydii CDC 3083-94
Genome accession: NC_010658
Putative virulence/resistance : Virulence
Product : lysine decarboxylase, constitutive
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG1982
EC number : 4.1.1.18
Position : 196556 - 198697 bp
Length : 2142 bp
Strand : +
Note : identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711

DNA sequence :
ATGAACATCATTGCCATTATGGGACCGCATGGCGTCTTTTATAAAGATGAGCCCATCAAAGAACTGGAGTCGGCGCTGGT
GGCGCAAGGCTTTCAGATTATCTGGCCACAAAACAGCGTTGATTTGCTGAAATTTATCGAACATAACCCTCGAATTTGCG
GCGTGATTTTTGACTGGGATGAGTACAGTCTCGATTTATGCAGCGATATCAATCAACTTAATGAATATCTCCCGCTTTAT
GCCTTCATCAACACCCACTCGACGATGGATGTCAGCGTGCAGGATATGCGGATGGCGCTCTGGTTTTTTGAATATGCGCT
GGGGCAGGCGGAAGATATCGCCATTCGTATGCGTCAGTACACCAACGAATATCTTGATAACATTACGCCGCCGTTCACGA
AAGCCTTGTTTACCTACGTTAAAGAGCGGAAGTACACCTTTTGTACGCCGGGGCATATGGGCGGCACCGCATATCAAAAA
AGCCCGGTTGGCTGCCTGTTTTATGATTTTTTCGGCGGGAATACCCTCAAGGCTGATGTCTCTATTTCGGTCACCGAGCT
TGGTTCGTTGCTCGACCACACCGGGCCACACCTGGAAGCGGAAGAGTACATCGCGCGGACTTTTGGCGCGGAACAGAGTT
ATATCGTTACCAACGGAACATCGACGTCGAACAAAATTGTGGGTATGTACGCCGCGCCATCCGGCAGTACGCTGTTGATC
GACCGCAATTGTCATAAATCGCTGGCGCATCTGTTGATGATGAACGATGTAGTGCCAGTCTGGCTGAAACCGACGCGTAA
TGCGTTGGGGATTCTTGGTGGGATCCCGCACCGTGAATTTACTCGCGACAGCATCGAAGAGAAAGTCGCTGCCACCACGC
AGGCACAATGGCCGGTTCATGCGGTGATTACCAACTCCACCTATGATGGCTTGCTCTACAACACCGACTGGATCAAACAG
ACGCTGGATGTCCCGTCGATCCACTTCGATTCCGCCTGGGTGCCGTACACCCATTTTCATCCGATCTACCAGGGGAAAAG
TGGTATGAGCGGCGAGCGTGTTGCGGGAAAAGTGATCTTCGAAACGCAATCGACCCACAAAATGCTGGCGGCGTTATCGC
AGGCTTCGCTGATCCACATTAAAGGCGAGTATGACGAAGAGGCGTTTAACGAAGCCTTTATGATGCATACCACCACCTCG
CCCAGTTATCCCATTGTTGCTTCGGTTGAGACGGCGGCGGCGATGCTGCGTGGTAATCCGGGCAAACGGCTGATTAACCG
TTCGGTGGAGCGGGCGCTGCATTTTCGCAAAGAGGTCCAGCGGTTGCGGGAAGAGTCTGACGGTTGGTTTTTCGATATCT
GGCAACCGCCGCAGGTGGATGAAGCCGAATGCTGGCCCGTTGCGCCAGGCGAACAGTGGCACGGCTTTAACGATGCGGAT
GCCGATCATATGTTTCTCGATCCCGTTAAAGTCACTATTTTGACACCGGGGATGGACGAACAGGGCAATATGAGCGAGGA
GGGGATCCCGGCGGCGCTGGTGGCAAAATTCCTCGACGAACGTGGGATCGTAGTAGAGAAAACCGGCCCTTATAACCTGC
TGTTTCTCTTTAGTATTGGTATCGATAAAACCAAAGCAATGGGATTATTGCGTGGGTTGACGGAATTTAAACACTCTTAC
GATCTCAACCTGCGGATCAAAAATATGCTACCCGATCTCTATGCTGAAGATCCCGATTTCTACCGCAATATGCGTATTCA
GGATCTGGCGCAAGGGATCCATAAGCTGATTCGTAAACACGATCTTCCCGGTTTGATGTTGTGGGCATTCGATACTTTGC
CGGAAATGATCATGACGCCACATCAGGCATGGCAGAGACAGATTAAAGGTGAAGTAGAAACCATTGCGCTGGAACAACTG
GTCGGTAGAGTATCGGCAAATATGATCCTGCCTTATCCACCGGGCGTACCGCTGTTGATGCCAGGAGAAATGCTGACCAA
AGAGAGCCGCACGGTACTCGATTTTCTACTGATGCTTTGTTCCGTAGGGCAACATTACCCCGGTTTTGAAACGGATATTC
ACGGCGCGAAACAGGACGAAGACGGCGTTTACCGCGTACGAGTCCTAAAAATGGCGGGATAA

Protein sequence :
MNIIAIMGPHGVFYKDEPIKELESALVAQGFQIIWPQNSVDLLKFIEHNPRICGVIFDWDEYSLDLCSDINQLNEYLPLY
AFINTHSTMDVSVQDMRMALWFFEYALGQAEDIAIRMRQYTNEYLDNITPPFTKALFTYVKERKYTFCTPGHMGGTAYQK
SPVGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARTFGAEQSYIVTNGTSTSNKIVGMYAAPSGSTLLI
DRNCHKSLAHLLMMNDVVPVWLKPTRNALGILGGIPHREFTRDSIEEKVAATTQAQWPVHAVITNSTYDGLLYNTDWIKQ
TLDVPSIHFDSAWVPYTHFHPIYQGKSGMSGERVAGKVIFETQSTHKMLAALSQASLIHIKGEYDEEAFNEAFMMHTTTS
PSYPIVASVETAAAMLRGNPGKRLINRSVERALHFRKEVQRLREESDGWFFDIWQPPQVDEAECWPVAPGEQWHGFNDAD
ADHMFLDPVKVTILTPGMDEQGNMSEEGIPAALVAKFLDERGIVVEKTGPYNLLFLFSIGIDKTKAMGLLRGLTEFKHSY
DLNLRIKNMLPDLYAEDPDFYRNMRIQDLAQGIHKLIRKHDLPGLMLWAFDTLPEMIMTPHQAWQRQIKGEVETIALEQL
VGRVSANMILPYPPGVPLLMPGEMLTKESRTVLDFLLMLCSVGQHYPGFETDIHGAKQDEDGVYRVRVLKMAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA NP_756988.1 lysine decarboxylase, inducible Not tested PAI II CFT073 Protein 0.0 69
unnamed CAD66195.1 putative cadaverin decarboxylase Virulence PAI III 536 Protein 0.0 61

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ldcC1 YP_001878988.1 lysine decarboxylase, constitutive VFG1670 Protein 0.0 61