Gene Information

Name : Amuc_0738 (Amuc_0738)
Accession : YP_001877355.1
Strain : Akkermansia muciniphila ATCC BAA-835
Genome accession: NC_010655
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 873861 - 875384 bp
Length : 1524 bp
Strand : +
Note : TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: glutamine amidotransferase class-I; GMP synthase domain protein; KEGG: tme:Tmel_0718 GMP synthase, large subunit

DNA sequence :
ATGGACGACAAGCACCTCGTAGCCGTCATTGACTTCGGCTCCCAATACACCCAGCTCATCGTACGCCGCGTGCGCGAACT
GGGCTACATGGCCAAGCTGTATGCGCTGGAAGACCTGGACCAGATTCACGAACCCGGCGCCGTCATCCTTTCCGGCGGCC
CCAAAAGCACCACGGATGCGGACGCCCCGGACATTGACTTTGAATGGCTCCAAAGCCTGAATGTCCCCGTCCTGGGCGTG
TGCTACGGCATGCAGCTGCTGAACATCAAGCACGGCGGCACCGTAAAAGCCAGCAACAAGCGGGAATACGGCCCCGCCGC
CCTGCTGCCGGAAACCTGCGTGGGCCTGTACCGGGACATGTCCCCTTCCTCCCAGGTATGGATGAGCCATTCGGACACGG
TGGACCATCTGGCGGAAGGCTGCCGCGTAATCGCCCGCAATGCGGAAGGCGTCCCCGTCTCCCTCCAATGGGGAGAAACC
ACCTTCGGCATCCAATTTCATCCGGAAGTGACCCATTCCCATGAAGGGCGCACCATCCTGCGCAACTTCCTTTCCTGTGC
GGCCAACCTTAAAAAGTTCGACATCGGAGACTTTAAAAGGGAACTCATCCGGGAAATCCGGGAACGCGTAGGCAACAGGC
AGGTGGTCTGCGGCGTCTCCGGCGGCGTGGACAGCACCGTTCTGGCCGTTCTGTTGCATGAAGCGGGCGTGAACATGCGC
GCCATCTTTGTGGATAACGGTCTGCTCCGCAAAAACGAGGCAGAGGAAGTGCGGGCCAATTTCGCCCGTATGAACGTGGA
AATTGAAACGGTGGATGCCTCCGAACGCTTCCTGGCGGCTCTGGACGGAGAAAGCGATCCGGAAAAGAAACGCCGTATCA
TCGGAGGCCTGTTCATCGACGTTTTCTGGGATGCCGTGGGAGACGCGGAAATGCTCGCCCAGGGCACCCTGTACCCGGAC
GTGATCGAAAGCGCCTCCAACGCCAAATCCAAGGCCTCCGTCATCAAGACCCACCACAATCGCGTGGAACGCGTGCTGGA
ACTCCAGGCGCAGGGGAAAGTACTGGAACCCCTGGCGGAACTGTTCAAGGACGAAGTTCGAGAACTGGGCGCCTCCATGG
GCATCCCGCATGACATTCTGTGGCGCCACCCCTTCCCCGGCCCCGGCCTGGCCGTGCGCTGCCCCGGCGTAGTCACCAAA
GAACGCCTGGACATCATCCGGGAATGCGATGCCATTTTCATCGGCAATCTGAAAAAATACGGCTGGTACGACAAAGTCTG
GCAGGCCTATGCCGGCCTCATCCCTGTAAAAACGGTGGGAGTGAAGGGGGACGAACGCTCCTATGAATGGGCTACCAACC
TGCGCGCCATCGTGTCGGAAGACGCCATGACGGCGGACTGGGTGGAACTCCCCCCGGCCCTGCTGAGGGAAACCAGCAAC
CGCATCCTCAATGAAGTAAAGGGCATCAACCGCGTCCTTTACGACATTTCCACCAAGCCCCCGGCTTCCATTGAGTGGGA
GTAA

Protein sequence :
MDDKHLVAVIDFGSQYTQLIVRRVRELGYMAKLYALEDLDQIHEPGAVILSGGPKSTTDADAPDIDFEWLQSLNVPVLGV
CYGMQLLNIKHGGTVKASNKREYGPAALLPETCVGLYRDMSPSSQVWMSHSDTVDHLAEGCRVIARNAEGVPVSLQWGET
TFGIQFHPEVTHSHEGRTILRNFLSCAANLKKFDIGDFKRELIREIRERVGNRQVVCGVSGGVDSTVLAVLLHEAGVNMR
AIFVDNGLLRKNEAEEVRANFARMNVEIETVDASERFLAALDGESDPEKKRRIIGGLFIDVFWDAVGDAEMLAQGTLYPD
VIESASNAKSKASVIKTHHNRVERVLELQAQGKVLEPLAELFKDEVRELGASMGIPHDILWRHPFPGPGLAVRCPGVVTK
ERLDIIRECDAIFIGNLKKYGWYDKVWQAYAGLIPVKTVGVKGDERSYEWATNLRAIVSEDAMTADWVELPPALLRETSN
RILNEVKGINRVLYDISTKPPASIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-94 44
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-94 44
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-94 44
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-83 42