Gene Information

Name : Amuc_0059 (Amuc_0059)
Accession : YP_001876686.1
Strain : Akkermansia muciniphila ATCC BAA-835
Genome accession: NC_010655
Putative virulence/resistance : Virulence
Product : ATPase AAA
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 77975 - 80557 bp
Length : 2583 bp
Strand : +
Note : PFAM: UvrB/UvrC protein; ATPase AAA; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: pcu:pc1511 probable endopeptidase ATP-binding chain ClpC

DNA sequence :
ATGAATAATTTTACGCCTAGGGCGCAACAAGTGCTGGCGCATGCGCGCCGGGAAGCGGACCGCTTCAATCATCATTACAT
AGGAACCGAACACCTTCTGCTCGGCCTGCTCAAGCTGGGCAAGGGCGTGGCCGTCACCATCCTGGAAAATCTGGGCGTGG
AGCTTACCGCCGTGCGCAAACAGGTGGAGGAACAAATAGGCCGGGGCACGGAACCCCAGGCGGAGGGCAACATCCCGTAC
ACCCCCAGGGTGCGCAAAGTCCTGGCAATGGCAAACAGGGAAGCCCAGGAACTCAACCACACGTATGTGGGCACGGAACA
CCTGCTCCTGGGCCTCATCCGTGACGGCGACGGCGTGGCCGGACAGATTCTGCGCCACTTCGGCGTGGATTTGGAACAAG
CGCGGCGCGAATTGCTGGACGTGCTGACCCCCAAATACCAGATGGATGCGGATGAAGACAACATCATCCCGGACGACGAT
GACGACGAGGAGGAAAATGAATCCCCCGCCATCCCGACGGACGAGCCTTCCTCCCCCTCCTACTCCAGGCAGCAGAAATC
CAAGACACCCGCGCTCCAGGCCTTTGGCCGGGACATGACCCAGCTGGCCCGGGACGGCAAGCTGGATCCCGTCATCGGCC
GCGCCTCGGAAATTGAGCGCGTCATCCAGATTCTGTGCCGGAGGAACAAAAACAACCCCGTCCTGCTCGGTGAAGCCGGG
GTGGGCAAAACCGCCATCGTGGAAGGGCTGGCCCAGGAAATAGCCCAGGGCCATGTTCCGGAGCTCCTGCGCAGCAAGAG
GGTCATCTCCCTGGACCTGGCGCTGATGGTGGCTGGCACCAAATACCGCGGTCAGTTTGAGGAACGGCTTAAGGCCGTAA
TGGATGAAATACGCCGGGAAGGCAATGTCATCCTTTTCATTGATGAACTGCACACCATCGTAGGCGCCGGCTCCGCGGAA
GGCTCCATGGACGCCTCCAACATCATCAAGCCCGCCCTCTCCCGGGGTGAGCTCCAGGCCATAGGCGCCACCACGCTCAA
CGAATACAGGAAACACATTGAGAAGGACGCCGCCCTGGAACGCCGCTTCCAGCAGGTGCAGGTAGGGGAACCCTCCGTGG
AGGACACCATCCAGATTCTTGCCGGGATCCAGCCCAAGTATGAGGAACATCACAAGGTGCATTATACGAAGGAAGCCGTT
GAAGCCGCAGCCAAGCTCTCCCACCGCTATCTGACGGGCCGGTTCCTGCCGGACAAGGCCATCGACATCCTGGATGAAGC
GGGCGCGCGCAAGCGCGTCTCCCAGATGACCCGCCCGGACCACATCAGCAACATGGAAATCCGCATTGCGGAAATCAAGG
AACGCAAGGACAAGGCTGTGGAAACCCAGCTTTTTGAAGAAGCAGCCCGCCTGCGCGACGAGGAAAAACAAGCCAAGGCG
GAACTTCAGAACATGCTGGAAACCTGGCGCAACTCCTATGAGACCAACTACGTTCCCGTGACGGATGAAGACGTGATGAG
CGTACTCGCCAAATGGACGGGCATCCCGCTGGCCCGGATGGAGGAAAAGGAAACCACCAAGCTTCTGCGGATGGAGGAAG
AGTTGAAAAGCAAAGTCATCGGCCAGGACGAGGCGGCTTCCGCCATCGCCCGCGCTCTGCGGCGCAGCCGTGCGGATATC
AAGGATCCGCGCCGCCCGATCGGCTCATTCCTCTTCCTGGGCCCCACCGGCGTGGGCAAAACCTATCTGGCCCGCAATCT
GGCGGAAATCATGTTCGGTACCTCGGACGCCCTGATTCAGGTGGACATGAGCGAGTACATGGAAAAACACACCACGTCCC
GTCTCATCGGTTCTCCTCCCGGCTATGTAGGCCATGACGAAGGCGGACAGCTCACGGAAGCCGTCCGGCGCAGGCCCTAC
TCCGTCATCCTCTTTGATGAAGTGGAAAAGGCCCATCCGGACGTCATGAACCTGCTTCTCCAGATTTTGGAAGAAGGCAG
CGTAACAGACTCGCTGGGACGCAAGATCAACTTCCGCAACACCATCATCATCCTGACCTCCAATGTGGGGGCCGCTTCCG
CCAAACGGCAGAGCACCATGGGCTTCGGCGCCATGGCCGCCGACAACGCGGACTACGCCGCCATGAAGGAAAAGATTCTG
GAAGCGGCGCGCAAGCAATTCCGGCCGGAATTCCTGAACCGATTTGATGACATTTCTGTCTTCCGCATGCTGGAACGGGA
CGACCTGGAACGCATCGTGCATCTGGAAGCGGACAAGCTCATCTCCCGTCTCAAGACCAAGAATATCACGCTTGCCCTGA
GCCAGGAAGCTCTGAGCCTGATCATCAAGAACGGCTATGACCCGCAGTACGGCGCCCGCCCGATGCGCCGCGCCATCGAA
CGCCTGCTGGAAGACCCGCTGGCGGAATCCCTGCTGAGGGGAGACGTGAAACCCGGCGATAAAATTGAAGCCGTGGAAAC
GGACGGGACGGAGACGCTCACCTTCCTGCACATCAAGGACAAAAAACCAGCCAGGCCCAAAGCGCCGCGCAAGAGAACGC
CGCGGAAACCCAAGGCGGAATAA

Protein sequence :
MNNFTPRAQQVLAHARREADRFNHHYIGTEHLLLGLLKLGKGVAVTILENLGVELTAVRKQVEEQIGRGTEPQAEGNIPY
TPRVRKVLAMANREAQELNHTYVGTEHLLLGLIRDGDGVAGQILRHFGVDLEQARRELLDVLTPKYQMDADEDNIIPDDD
DDEEENESPAIPTDEPSSPSYSRQQKSKTPALQAFGRDMTQLARDGKLDPVIGRASEIERVIQILCRRNKNNPVLLGEAG
VGKTAIVEGLAQEIAQGHVPELLRSKRVISLDLALMVAGTKYRGQFEERLKAVMDEIRREGNVILFIDELHTIVGAGSAE
GSMDASNIIKPALSRGELQAIGATTLNEYRKHIEKDAALERRFQQVQVGEPSVEDTIQILAGIQPKYEEHHKVHYTKEAV
EAAAKLSHRYLTGRFLPDKAIDILDEAGARKRVSQMTRPDHISNMEIRIAEIKERKDKAVETQLFEEAARLRDEEKQAKA
ELQNMLETWRNSYETNYVPVTDEDVMSVLAKWTGIPLARMEEKETTKLLRMEEELKSKVIGQDEAASAIARALRRSRADI
KDPRRPIGSFLFLGPTGVGKTYLARNLAEIMFGTSDALIQVDMSEYMEKHTTSRLIGSPPGYVGHDEGGQLTEAVRRRPY
SVILFDEVEKAHPDVMNLLLQILEEGSVTDSLGRKINFRNTIIILTSNVGAASAKRQSTMGFGAMAADNADYAAMKEKIL
EAARKQFRPEFLNRFDDISVFRMLERDDLERIVHLEADKLISRLKTKNITLALSQEALSLIIKNGYDPQYGARPMRRAIE
RLLEDPLAESLLRGDVKPGDKIEAVETDGTETLTFLHIKDKKPARPKAPRKRTPRKPKAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Amuc_0059 YP_001876686.1 ATPase AAA VFG0079 Protein 0.0 54
Amuc_0059 YP_001876686.1 ATPase AAA VFG0080 Protein 1e-146 53