Gene Information

Name : Amuc_0346 (Amuc_0346)
Accession : YP_001876966.1
Strain : Akkermansia muciniphila ATCC BAA-835
Genome accession: NC_010655
Putative virulence/resistance : Virulence
Product : DNA mismatch repair protein MutS
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0249
EC number : -
Position : 407251 - 409722 bp
Length : 2472 bp
Strand : -
Note : TIGRFAM: DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS domain protein; MutS III domain protein; MutS II domain protein; MutS IV domain protein; KEGG: gme:Gmet_1424 DNA mismatch repair protein

DNA sequence :
ATGATGGATCAGTACCTTCGCATGAAGAAGGGCTTGCCGGAAGACGTGCTGCTGTTTTTCCGGCTGGGGGATTTTTACGA
AATGTTTTTTGAGGACGCCAAGGAGGCCTCCGCCATTTTGGGCCTGACGCTGACCAAGCGCCACGGTATTCCCATGTGCG
GGGTGCCCCACCACAGCGCGGAAGGGTATATCGGACGGCTGGTGAAGGGAGGAAAGCGGGTGGCTATTGCGGAGCAGACC
ACCATTCCGCAGCCGGGCAAGCTGGTGGAGCGGGAACTGACCCGCGTGATTTCCGCCGGAACCCTGGCGGATATGAATTT
GCTGGATTCCTCCCGCCATAATTACATTGTGGCGTTGTACAAGGACAAGAAGCGCTTCGGCCTGGCATGCGTGGACCATA
CCACGGGGGAATTTTCCGTGGCCCAGTTCGAACACATGGATTTGCTTCTGGACGAGCTGTCCCGCATCAATCCCTCCGAA
CTCCTGGTCAGCGACGAGCAGACGGACTGCTTCCCCGGAACCCACCCCACGCTTTATTACGACGGATATACTTTTCTGCC
TTCCACGGCCATTCCCAATTTGCTGAACCATTTCCGGGTGCATTCCCTGGACGGTTTCGGCTGCGGGGAGATGACCGCCG
CTCTGGGGGCGTCCGGCGCGGTGCTCCATTATCTGGGCTACCAGCTCCGCCGCCCCACGGACCACCTGCGCCGCATTTCC
GTGCGCGCCACGGAGAACGCCGTGCTGATTGACCAGGCCAGCCAGAGGAATCTGGACCTGGTGGATTCCCGCGGCGGCGT
GAAGCTTTCCCTGCTGGGGACCCTGGACAGGACGAGCACCCCCATGGGCGCGCGCAAACTCCGGGACTGGCTGCTCCACC
CCCTGTGTGATCTGGAAAAGCTCCTGGCGAGGCAGGAGGTGATCGCCGTTCTGCTTCAGGAACCCTACCTGATGAGCAAG
CTGAGGGAGAGCCTGAAGAATGTGCGGGACATGGAGCGGCTGACGGGGCGCATTTCCCAGGGCGCCGGGAATGCCCGCGA
CCTCCAGGCGCTGGCTTCCTCCCTGGCGCGCATTCCCGCGCTCAGGGATGATCTGGAATCCCTGCCCGGCGGCGGGGACA
TGCTGGAGAGCATCCGTTCCCGCATGGGCTGCTTTGATGAGCTGGTGGATTTGCTCCAGCGCGCTCTGGTGGATGAACCT
CCCGTGACCATCAAGGAGGGAGGCATCATCAGGGAAGGGTACCATGCCGGTCTGGATGAATTGCGTCTGGCTTCCCGCGA
CGGGAAGGAGTGGCTGGCACGGCTGCAGGAGAAGGAGCGCAAGCGCACGGGAATTGATTCCCTGAAAATCCGCTTCAATA
ACGTCTTCGGCTATTACATTGAAGTAACGAAGAGCCATTACGATAAAGTGCCCCCGGATTACCAGCGCAAGCAGACGCTG
GTGAATGCGGAGCGCTTTATTACCCCGGAACTCAAGCAGATGGAGAATACCATCTTGGGGGCGGACGAGCGTTCCCGCCA
GGTGGAGTATGAGCAGTTCCTCCTGTTGCGCGAGGAAGTGGGGCGCCACATTGACGATATCCAGATTACGGCGGATGCCA
TGGCGGACCTGGACGTGCTGCTGGGGCTGGCGGAGGGGGCCCAGCAGTACCGGTATTGCCGCCCCGTTCTGGACAATTCC
ATGACCCTGCGCATTGTCAATGGCCGTCATCCCGTTATTGAGCAGAATGTTTCCGGCGATGTGTTCGTTCCCAATGACGC
TTTTCTGGAACCGGAGGAAAACCGCCTTATTCTGCTGACCGGGCCCAATATGGCGGGCAAGAGCACCTATATCCGCCAGG
TGGCCCTGATTACGCTGATGGCCCAGATTGGAGCGTATGTGCCGGCGGAGTCCGCCCATATCGGTTTGGTGGACCGCATT
TTCTGCCGCGTGGGAGCCAGCGACGACCTGGCGCGCGGCCAGTCCACCTTTATGGTGGAGATGAGCGAAACCTCCCTGAT
TCTGAATAATGCCACGGAGCGCTCCCTGATTATTCTGGATGAAATCGGGCGAGGCACGGCCACTTTTGACGGGCTTTCCA
TTGCCTGGGCCGTGGCGGAGTACCTGCATGACGAGTTGAAGTCCCGCACCCTGTTCGCCACGCATTATCATGAGCTGACG
GATTTGGCCAATTCCAGGCAGGGCGTGCAGAATTACAATGTGGCCGTGCGCGAGTGGAAGGAGGAAATCGTGTTTCTGCG
CAAGATCGTGCCGGGGGCGGCGGATAAGTCCTACGGCATCCAGGTGGCCCGACTGGCCGGCATGCCTGCCGTCATTGTGG
ACCGCGCCAAGGCCATCCTGTCCCATCTGGAGATGAATTCCACGCGCCCCCGGAGGAAGGAGCGCTCCCGGCTGGCGGAA
CCGAGAGCCAAGAATACGGATATGGAAGACGATATGCCTGCCGGGGAATATGCTCAGCTGGAGTTGTTCTGA

Protein sequence :
MMDQYLRMKKGLPEDVLLFFRLGDFYEMFFEDAKEASAILGLTLTKRHGIPMCGVPHHSAEGYIGRLVKGGKRVAIAEQT
TIPQPGKLVERELTRVISAGTLADMNLLDSSRHNYIVALYKDKKRFGLACVDHTTGEFSVAQFEHMDLLLDELSRINPSE
LLVSDEQTDCFPGTHPTLYYDGYTFLPSTAIPNLLNHFRVHSLDGFGCGEMTAALGASGAVLHYLGYQLRRPTDHLRRIS
VRATENAVLIDQASQRNLDLVDSRGGVKLSLLGTLDRTSTPMGARKLRDWLLHPLCDLEKLLARQEVIAVLLQEPYLMSK
LRESLKNVRDMERLTGRISQGAGNARDLQALASSLARIPALRDDLESLPGGGDMLESIRSRMGCFDELVDLLQRALVDEP
PVTIKEGGIIREGYHAGLDELRLASRDGKEWLARLQEKERKRTGIDSLKIRFNNVFGYYIEVTKSHYDKVPPDYQRKQTL
VNAERFITPELKQMENTILGADERSRQVEYEQFLLLREEVGRHIDDIQITADAMADLDVLLGLAEGAQQYRYCRPVLDNS
MTLRIVNGRHPVIEQNVSGDVFVPNDAFLEPEENRLILLTGPNMAGKSTYIRQVALITLMAQIGAYVPAESAHIGLVDRI
FCRVGASDDLARGQSTFMVEMSETSLILNNATERSLIILDEIGRGTATFDGLSIAWAVAEYLHDELKSRTLFATHYHELT
DLANSRQGVQNYNVAVREWKEEIVFLRKIVPGAADKSYGIQVARLAGMPAVIVDRAKAILSHLEMNSTRPRRKERSRLAE
PRAKNTDMEDDMPAGEYAQLELF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
mutS AAA80578.1 DNA mismatch repair protein Virulence SPI-1 Protein 7e-135 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Amuc_0346 YP_001876966.1 DNA mismatch repair protein MutS VFG0562 Protein 5e-152 43