Gene Information

Name : Amuc_0183 (Amuc_0183)
Accession : YP_001876808.1
Strain : Akkermansia muciniphila ATCC BAA-835
Genome accession: NC_010655
Putative virulence/resistance : Resistance
Product : Beta-lactamase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG2367
EC number : 3.5.2.6
Position : 230995 - 231915 bp
Length : 921 bp
Strand : -
Note : PFAM: beta-lactamase; KEGG: aby:ABAYE3623 extended spectrum beta-lactamase VEB-1

DNA sequence : 
ATGACTTCCACCGGTGTTTATCTATGCGGTTGCATCATGTTCTTTTGCGTTTTTTCTCAGGGGGCCACGTCTTCTCCGCC
AGCCGTTTCCGCAGCGGATTCCTCCGCCGTACGCGAACTGGCCCATTCCCTGAAGGCCCGTGTGGGCATGGCTGCGGAAA
TGCTGGATACGGGGGAAACCGTCATGGTGGGGGATGAGGCGGCCTATCCCATGCAGAGCGTCGTCAAATTCGTGCTGGCC
TTGTCCGTCTTGAAGCGGGTGGACCAGGGCGCCATGAATCTGGAACAGATCATCCGCATACGTCCGGAACAACTGGTGAA
AGATACCTGGAGCCCCCTCCGGGAGCGTTTCCCGCAAGGCGGCGATTTCTCTCTGAAGGAACTGCTGAGAGTGACTGTCC
AGGAAAGCGACAACAATACCTGCGACCTCCTGTTTGGCCTTATTGGAGGGCCGCAGGCCGTGCAGAAGGATTTGAAGGAA
TGGGGAATTGACGGCATTAATGTCCGTTTTACGGAAGAAGAAATACACCGGAATCATGATTTGCAATATGTCAACTCAAG
CCGTCCGTCGGCCATGAACTCCCTTCTCCGGGCGTTTGACGAAGGTAAAATTTTGAAAAAAGGCACACAGAGTGTTCTTT
GGAACATCATGGCGGGATGTTCTACAGGTCCTGAACGTCTGAAAGGGCAGCTGCCGCGGGATTACGTGGTGGCGCATAAG
ACGGGATCCGGATTCACGCTGCCGGGGGGTGGCGTTACCGCCCGCAATGACGTCGGCATCATTGTTCTTCCCAACGGCCG
GAAAATGGCGGTTTCCGTGTTCATCAGGGATTCAAAGGATTCTGAATCCGCTTGTGACCGGGTGATCGCCTCCATGGCCC
GCTGGCTGTGCCTGGAATGGCTGGGTGCCGGAGGCAGGTAA

Protein sequence : 
MTSTGVYLCGCIMFFCVFSQGATSSPPAVSAADSSAVRELAHSLKARVGMAAEMLDTGETVMVGDEAAYPMQSVVKFVLA
LSVLKRVDQGAMNLEQIIRIRPEQLVKDTWSPLRERFPQGGDFSLKELLRVTVQESDNNTCDLLFGLIGGPQAVQKDLKE
WGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILKKGTQSVLWNIMAGCSTGPERLKGQLPRDYVVAHK
TGSGFTLPGGGVTARNDVGIIVLPNGRKMAVSVFIRDSKDSESACDRVIASMARWLCLEWLGAGGR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
bla VEB-1 CAJ77043.1 Betalactamase Not tested AbaR1 Protein 3e-46 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Amuc_0183 YP_001876808.1 Beta-lactamase AY536519.1.gene1.p01 Protein 3e-46 41
Amuc_0183 YP_001876808.1 Beta-lactamase NC_010410.6002875.p0 Protein 2e-46 41
Amuc_0183 YP_001876808.1 Beta-lactamase AF010416.1.gene1.p01 Protein 2e-46 41
Amuc_0183 YP_001876808.1 Beta-lactamase AY027870.1.gene1.p01 Protein 2e-46 41