Gene Information

Name : Amuc_1585 (Amuc_1585)
Accession : YP_001878186.1
Strain : Akkermansia muciniphila ATCC BAA-835
Genome accession: NC_010655
Putative virulence/resistance : Virulence
Product : type II secretion system protein E
Function : -
COG functional category : N : Cell motility
COG ID : COG2804
EC number : -
Position : 1905728 - 1907386 bp
Length : 1659 bp
Strand : -
Note : PFAM: type II secretion system protein E; General secretory system II protein E domain protein; SMART: AAA ATPase; KEGG: rba:RB12774 type IV fimbrial assembly protein PilB

DNA sequence :
ATGGACACCAACCTCACACTGGAACTTTTCATCGGCCGGGGAATGATTGACAAATCCCTGGCAAAGGACATCAAGGAGGA
AATGATCGCCTCCGGCAAGGAGCTGCCGGAAGTGCTTGCAGACTTCGGCATCATCGGCAGCAAGGATGATATCTGGCAGA
TGATTGCCAGCGACCTGGGTACGGAATTCATTACACTGGACAACTTCCAGCCGGATCCGAACGTGCAGAACATGATGCCG
GCCACGCTCGTGCGCCTGCACGGGGCGCTCCCTGTGCGGCATGGTCCGGAAGGCCTGTACGTCTGCCTGGTGGATCCCCT
GAATCCCCAGACGGTGGAAGACCTGCGCTTCGCCCTCGGCCAGGACATCCATGTTCTGGTAGCGCCGGATTACCAGATTT
CCGAACGCATCAATGAGCTTTATGGAGGCGAATCCGCCGCCATGTCCGACCTGATGCAGGAGCTGAACAACATGCAGGTC
AACAATGAGACGGAGGACTCCGCCGCCGCTCCCGTCATCCGCTTTGTGGACCTCGTCATTACGCAGGCCATCAAGGAAAA
GGCCTCCGACATTCACTTCGAACCTTTTGAGAAGGAATTCAAAATCCGCTACCGTGTGGACGGCGCCCTGTATGAAATGC
AGCCTCCCCCCGTCCACCTGTCCGTGCCGGTCATTTCCCGCGTCAAAGTCATGGCGAACATGAACATCGCGGAACGCCGC
ATTCCGCAGGACGGACGCATCGTCAAGCAGATAGGAAACCGTTCCGTGGACATGCGCGTTTCCTCCCTTCCCACTCAGTA
CGGAGAATCCGTGGTGCTCCGCGTTCTGGACCGCTCTTCCGTCAACTTGAACATGGACAACCTGGGGCTTCCCGCGCATA
TCCACGAATATATTCTGGATACGGTCCACAAGCCCAACGGCATTTTCATCGTTACCGGCCCCACCGGCGCCGGCAAGACA
ACTACGCTGTATGCCGCCCTGCGTGAAATCAATACCATTGATTCCAAGGTGCTGACGGCGGAAGACCCTGTTGAATACGA
TATTGACGGCATCATCCAGATTCCTATCAATGAAGCCATCGGCCTGGACTTCCCAATGGTGCTCCGCGCCTTCCTGCGAC
AGGACCCGGACCGTATTCTGGTGGGGGAAATGCGAGACATGGCAACAGCGCAGATCGCCATCCAGGCATCCCTGACGGGT
CACCTGGTTCTCTCCACCCTGCACACGAACGACTCCGCCGGAGCCATTACGCGACTGGTGGACATGGGATGCGAACCTTT
CCTGGTGGCGGCTTCCCTGGAAGGGGTGCTTGCACAGCGCCTGGTGCGCACCATCTGTCCGGACTGCCGCACGCCGTATG
AACCCTCATCCACCATCCTCTCCCAGCTTGGCGTCTCTCCCTATGAACTGGGAGACAAGCACTTTTTCACGGGCCGAGGC
TGTGATAAATGCTCCAATTCCGGCTACAGGGGCCGCAAGGGGATTTATGAGCTCCTGGATATTAACGATACCCTGCGCGA
CATGATTACGGATCGCGCTCCTTCCGTGGTGCTGAAGCAGAAAGCCATTGAAATGGGCATGTCCACGCTGCGGGAAGACG
GGCTGAGAAATATTTATGACGGCAACACCACCATTGAAGAAGTGCTGAAATATACTTAA

Protein sequence :
MDTNLTLELFIGRGMIDKSLAKDIKEEMIASGKELPEVLADFGIIGSKDDIWQMIASDLGTEFITLDNFQPDPNVQNMMP
ATLVRLHGALPVRHGPEGLYVCLVDPLNPQTVEDLRFALGQDIHVLVAPDYQISERINELYGGESAAMSDLMQELNNMQV
NNETEDSAAAPVIRFVDLVITQAIKEKASDIHFEPFEKEFKIRYRVDGALYEMQPPPVHLSVPVISRVKVMANMNIAERR
IPQDGRIVKQIGNRSVDMRVSSLPTQYGESVVLRVLDRSSVNLNMDNLGLPAHIHEYILDTVHKPNGIFIVTGPTGAGKT
TTLYAALREINTIDSKVLTAEDPVEYDIDGIIQIPINEAIGLDFPMVLRAFLRQDPDRILVGEMRDMATAQIAIQASLTG
HLVLSTLHTNDSAGAITRLVDMGCEPFLVAASLEGVLAQRLVRTICPDCRTPYEPSSTILSQLGVSPYELGDKHFFTGRG
CDKCSNSGYRGRKGIYELLDINDTLRDMITDRAPSVVLKQKAIEMGMSTLREDGLRNIYDGNTTIEEVLKYT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
gspE YP_854406.1 type II secretion protein GspE Not tested PAI I APEC-O1 Protein 2e-92 44
gspE CAE85233.1 GspE, hypothetical type II secretion protein Not tested PAI V 536 Protein 1e-92 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Amuc_1585 YP_001878186.1 type II secretion system protein E VFG1876 Protein 7e-86 48
Amuc_1585 YP_001878186.1 type II secretion system protein E VFG0182 Protein 5e-93 45
Amuc_1585 YP_001878186.1 type II secretion system protein E VFG2426 Protein 2e-74 44
Amuc_1585 YP_001878186.1 type II secretion system protein E VFG2048 Protein 9e-94 44