Gene Information

Name : Amuc_1435 (Amuc_1435)
Accession : YP_001878038.1
Strain : Akkermansia muciniphila ATCC BAA-835
Genome accession: NC_010655
Putative virulence/resistance : Unknown
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1004
EC number : 1.1.1.22
Position : 1720797 - 1722119 bp
Length : 1323 bp
Strand : -
Note : KEGG: aae:aq_024 nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP

DNA sequence :
ATGAATTTAACAATTATCGGCAGTGGTTACGTGGGGCTGACCACAGGCACCTGTTTTGCCGAAATGGGCCATCACGTCAT
TTGCGTGGATAATAATACGGAAAAAATACGTACTCTTCAATCCGGGGCCATCCCCATTTACGAGCCCAAGCTGGAAGAGC
TCGTGAAAAAAAACGTAGCCGTGGGGCGGCTGGAATTTTCCCCTTCCATCGCCGCTTCCATTGCGGAAAGCGAAGTCATC
TTCATCGCCGTGCCCACGCCGCCCAATACGGATGGTTCCGTGGACCTGACCTACATTGAAAAAGTGGCCAGGGAAATCGC
CCAGGCGCTCCAACCAGAAATGGGATACAAGGTCATTGTGGACAAATCCACCGTACCCGTCAAAACCGGGGAAAAAGTCA
GCCAGACCATCAAGCACTATGCGGGGCCGAATGTTCAGTTCGACATTGTCTCCAATCCAGAATTCCTGAGGGAAGGATGC
GCCGTGGACGACCTGCTGCACCCTGACCGCATTGTCATTGGAGCCAACTCGGAACAGGCCATGAACGTCATCAAGCGCGT
TTACCAGCCCATTCATGCCCCCATTCTGGAAACGGACGTCAACTCCGCGGAACTCATCAAGCACGCAGCCAACTCCTTCT
TGGCTCTGAAAATTTCCTACATTAACGCTGTCGCCAAGGTCTGTGAAAAAACGGGCGCAGACGTGGAACTGGTGGCGGAA
GGCATCGGCATGGACAAACGCATCTCACGCCACTTTCTCAACGCGGGGCTGGGCTACGGCGGGTCCTGCTTCCCGAAAGA
CGTCAAAGCCTTCATCAACATCAGCCGCACGCTGGGCATTCCCTTCACCCTGTTGGAGGAAGTGGAACACATCAATGATA
CCCAGCATATCCACTTCCTGGACAGAATTCGGGACCGCCTGTGGGTCCTCAAGGACAAAAAGATAGCCGTTTGGGGCCTT
GCCTTCAAACAGAACACGGACGACGTCCGGGAATCCATCGCCCTGAAACTATGTGAAAAACTCTGCGGGGAAGGAGCCAT
TGTCACCGCTACGGACCCCAAAGCCATGCACACGGCGGCCCCCATTCTGAACCCTATGGGGGTCAAACTGGTGGAAGACA
TGTACGAATGCGCCCGGGATGCGGAAGTTCTGGTCATCGCCACGGAATGGAGCGAATATGCGAATGCGGATCTGCAGAAA
CTCGCCGGAGTCATGCGCAACCGCATCATCTTTGACGGAAGAAACATCCTCTCCCCGGCAAACCTCCGGGCCGTAGGATT
TGAATACCACTCCGTGGGCAGACCCTCCGTTGAAGAAGCCTGA

Protein sequence :
MNLTIIGSGYVGLTTGTCFAEMGHHVICVDNNTEKIRTLQSGAIPIYEPKLEELVKKNVAVGRLEFSPSIAASIAESEVI
FIAVPTPPNTDGSVDLTYIEKVAREIAQALQPEMGYKVIVDKSTVPVKTGEKVSQTIKHYAGPNVQFDIVSNPEFLREGC
AVDDLLHPDRIVIGANSEQAMNVIKRVYQPIHAPILETDVNSAELIKHAANSFLALKISYINAVAKVCEKTGADVELVAE
GIGMDKRISRHFLNAGLGYGGSCFPKDVKAFINISRTLGIPFTLLEEVEHINDTQHIHFLDRIRDRLWVLKDKKIAVWGL
AFKQNTDDVRESIALKLCEKLCGEGAIVTATDPKAMHTAAPILNPMGVKLVEDMYECARDAEVLVIATEWSEYANADLQK
LAGVMRNRIIFDGRNILSPANLRAVGFEYHSVGRPSVEEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
udgA YP_005682185.1 UDP-glucose 6-dehydrogenase Not tested PiCp 7 Protein 9e-51 41
udgA YP_003784334.1 UDP-glucose 6-dehydrogenase Not tested PiCp 7 Protein 9e-51 41
udgA YP_005686369.1 UDP-glucose 6-dehydrogenase Not tested PiCp 7 Protein 9e-51 41