Gene Information

Name : dhpS (BAV0932)
Accession : YP_785459.1
Strain : Bordetella avium 197N
Genome accession: NC_010645
Putative virulence/resistance : Resistance
Product : dihydropteroate synthase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0294
EC number : 2.5.1.15
Position : 992638 - 993474 bp
Length : 837 bp
Strand : +
Note : -

DNA sequence :
ATGGTCCATTCTTTTTTGTGCGGGCGCTTTGAGCTGGATCTCGGGCGCCCGCTTGTCATGGGTATTGTCAATGTCACGCC
TGATTCCTTCTCGGATGGCGGCCTGCACAACGACCCGGACGCAGCCATCGCGCACGCCCATGCCCTGATTGCAGAAGGCG
CTCATATCCTCGATCTGGGCGGTGAATCCACACGCCCTGGTGCGCCGGCTGTGTCGGCCGACGAGGAAAAGCGGCGTTTG
CTGCCCGTCATCGAGGCGCTGCGTGATTGCGGTGTGCCGCTTTCCATCGACACCTTCAAGCCTGAGGTCATGCGTGCGGT
GCTCGATGTCGGCGCCGACATGATCAACGACATCTATGGTTTTCGTCTGCCGGGCGCGGTTCAAGCTGTTGCGGACTCGC
GTTGCGGCCTGTGCGTCATGCATATGCAGGGCGAACCGGGCACGATGCAGGACGCGCCGCAATACGCCGATGTCCTGGGT
GAGGTGCGCGGTTTCCTTGATGCCCGGGCAGACTGCCTGCTGGCCGCCTCGGTGGATGCGCGGCGCATCGTGCTCGACCC
CGGCTTCGGCTTCGGCAAAACCGCGAACCAGAATTATCAGTTACTGCGCGGGCTGGACAGCTTGCGCGACTATCCGCTGC
TGATTGGTGTCTCTCGCAAATCCATGATCGGCGCCGCCACCGGACGGCCCGTCGGCGAGCGTCTGCCCGGCAGCATTGCC
GCCGCCCTGGCCTGTGTGGCCCGTGGCGCTGCTATCGTGCGCGTGCACGATGTGGCCGCCACGGTGGATGCCCTGAAGGT
CTGGCAGGCGGCTGAACAAGGAGCCATCTTTTCATGA

Protein sequence :
MVHSFLCGRFELDLGRPLVMGIVNVTPDSFSDGGLHNDPDAAIAHAHALIAEGAHILDLGGESTRPGAPAVSADEEKRRL
LPVIEALRDCGVPLSIDTFKPEVMRAVLDVGADMINDIYGFRLPGAVQAVADSRCGLCVMHMQGEPGTMQDAPQYADVLG
EVRGFLDARADCLLAASVDARRIVLDPGFGFGKTANQNYQLLRGLDSLRDYPLLIGVSRKSMIGAATGRPVGERLPGSIA
AALACVARGAAIVRVHDVAATVDALKVWQAAEQGAIFS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00253 YP_008211579.1 Dihydropteroate synthase-related enzyme Not tested AbaR26 Protein 1e-24 42
sul2 AEZ06044.1 Sul2, sulphonamide-insensitive dihydropteroate synthase Not tested Tn6167 Protein 1e-24 41
sul2 AEA34678.1 dihydropteroate synthase Not tested Not named Protein 9e-25 41
sulI2 AFV47959.1 sulphonamide-insensitive dihydropteroate synthase SulI2 Not tested AbaR25 Protein 9e-25 41
ABK1_0255 YP_005512827.1 Dihydropteroate synthase type-2 Not tested AbaR4d Protein 1e-24 41
BJAB07104_00246 YP_008207711.1 Dihydropteroate synthase-related enzyme Not tested AbaR25 Protein 1e-24 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
dhpS YP_785459.1 dihydropteroate synthase CP002695.1.gene1085. Protein 2e-90 81
dhpS YP_785459.1 dihydropteroate synthase NC_008702.1.4608834. Protein 4e-67 62
dhpS YP_785459.1 dihydropteroate synthase NC_002516.2.881715.p Protein 3e-47 54
dhpS YP_785459.1 dihydropteroate synthase CP004022.1.gene3451. Protein 1e-47 53
dhpS YP_785459.1 dihydropteroate synthase NC_002695.1.916103.p Protein 3e-46 52
dhpS YP_785459.1 dihydropteroate synthase CP000034.1.gene3358. Protein 4e-45 52
dhpS YP_785459.1 dihydropteroate synthase CP000647.1.gene3624. Protein 5e-45 51
dhpS YP_785459.1 dihydropteroate synthase NC_010410.6003232.p0 Protein 2e-39 49
dhpS YP_785459.1 dihydropteroate synthase NC_011595.7059722.p0 Protein 2e-39 49
dhpS YP_785459.1 dihydropteroate synthase NC_011586.7045137.p0 Protein 2e-39 49
dhpS YP_785459.1 dihydropteroate synthase NC_010400.5986775.p0 Protein 4e-40 49
dhpS YP_785459.1 dihydropteroate synthase CP001138.1.gene3456. Protein 2e-43 49
dhpS YP_785459.1 dihydropteroate synthase CP000675.2.gene3019. Protein 2e-41 47
dhpS YP_785459.1 dihydropteroate synthase AM180355.1.gene1650. Protein 2e-34 44
dhpS YP_785459.1 dihydropteroate synthase AE000516.2.gene3902. Protein 2e-29 42
dhpS YP_785459.1 dihydropteroate synthase NC_009782.5559617.p0 Protein 6e-21 42
dhpS YP_785459.1 dihydropteroate synthase NC_002951.3237126.p0 Protein 6e-21 42
dhpS YP_785459.1 dihydropteroate synthase NC_007793.3915320.p0 Protein 2e-21 42
dhpS YP_785459.1 dihydropteroate synthase NC_009641.5330254.p0 Protein 2e-20 42
dhpS YP_785459.1 dihydropteroate synthase NC_002745.1123263.p0 Protein 6e-21 42
dhpS YP_785459.1 dihydropteroate synthase NC_013450.8613224.p0 Protein 6e-21 42
dhpS YP_785459.1 dihydropteroate synthase NC_003923.1002573.p0 Protein 2e-21 42
dhpS YP_785459.1 dihydropteroate synthase NC_002758.1120474.p0 Protein 6e-21 42
dhpS YP_785459.1 dihydropteroate synthase AE016830.1.gene3181. Protein 6e-26 41
dhpS YP_785459.1 dihydropteroate synthase DQ464881.1.gene2.p01 Protein 4e-24 41