Gene Information

Name : kdsB (BAV2102)
Accession : YP_786619.1
Strain : Bordetella avium 197N
Genome accession: NC_010645
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 2249228 - 2250052 bp
Length : 825 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
TTGAGCTTCGTCGCCCTCATCCCCGCACGCGCCGCGTCCATCCGGCTGCCCGATAAGCCGCTAGCGGATATCGCTGGCAA
GCCGATGGTGGTGCGGGTCGCCGAACGCGCCGCCCTGTCCGGCGCGAGTCTGGTCTGCGTCGCCACGGACGACACCCGGG
TTGAGAGAGCCGTCACAGAGCATGGTTTTCCTGCGGTCCGGACGCTGTCCAGCCACCCGACCGGCACCGATCGCCTGGCC
GAGGCGGTGCGTATCCTCGGACTGCCCGGCGATGCCATCGTGGTCAACGTGCAGGGTGACGAGCCTCTGATTGAACCGAC
CCTTATTGACGGCGTGGCGCAATTGCTGGCCGACAATCCGCAGGCTGACATCGCCACCTGCGCCTGCCCGCTGACCGATG
CCCAGGCCCTATTCAATCCCAACGTCGTCAAAGTGGTCTGCGGCAACGATGGCCGAGCGCTGTACTTCTCTCGCGCTCCT
ATTCCCTGGGCACGTGACGCCCTGGCGGGTGGCGAGCGTATGCTGGCGCCAGGCCTGCCCGCCTGGCACCACATCGGCCT
GTACGCTTACCGCGTCAGTTTTTTGCAGCGTTTCCCCACCCTGGCGCAGGGCGAGCTGGAACGTTTCGAATCGCTGGAGC
AGTTGCGCGCCATGGAACATGGGCACACGATTGTGGTCTCGCGCATTTCGGCAGCACCAGCGGCTGGCGTCGATACGCCT
GCCGACCTGGATCGCGTGCGCGCCATTTACCTTCAAGCGCCGAAAACCGAGGCAAACCAAGGCTTGATTCAGGTTCAATC
CGACCAAGGAAACGACGGGCGATAA

Protein sequence :
MSFVALIPARAASIRLPDKPLADIAGKPMVVRVAERAALSGASLVCVATDDTRVERAVTEHGFPAVRTLSSHPTGTDRLA
EAVRILGLPGDAIVVNVQGDEPLIEPTLIDGVAQLLADNPQADIATCACPLTDAQALFNPNVVKVVCGNDGRALYFSRAP
IPWARDALAGGERMLAPGLPAWHHIGLYAYRVSFLQRFPTLAQGELERFESLEQLRAMEHGHTIVVSRISAAPAAGVDTP
ADLDRVRAIYLQAPKTEANQGLIQVQSDQGNDGR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 6e-33 45
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 8e-33 45
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-32 45