Gene Information

Name : cadA (BAV1632)
Accession : YP_786152.1
Strain : Bordetella avium 197N
Genome accession: NC_010645
Putative virulence/resistance : Resistance
Product : cadmium-transporting ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 1704821 - 1707082 bp
Length : 2262 bp
Strand : -
Note : -

DNA sequence :
ATGTCTAAGCACCAGCTCTCCACCCCCGGCACCTGCTGCGCCCCTGGGCAACGCCCGGACGCGCGCGGCGACGCACACGA
ACACGAGCCTGCGCACAGCCATGATGGTGATGGCTGCTGCGCGTCGGCCGCAAGCCAGCCAAAGCAGAGTGGCAGCCAGC
TGAACGCAGGCTCGGGACAGACGCTGACGCGGCTGCGCATCGGCCAGATGGACTGCCCGACCGAGGAAACACTGATCCGC
AAAAAGCTGGGGAGCATGGCAGAAGTGCAGGCCATGGAATTCAACCTTATGCAGCGCATGCTGACCGTCGTGCATAGCGA
CGGCACGCTCGAACGCATTCTGGATGCCATCCGCAGCCTGGGCATGACCCCGGAAACGACGACCAGCGCCCCGCCGTCGC
AGAAAGCCGGATGGCGCTTGCTGGCCTTGGGCGGGGTCCTCGCCGGTCTCTCCGAGGCCGCGCATTTTGCGGGCCAGCAC
CCCTGGCTGACCGCCCTGCTCTCGCTGGCCGCTATTGCCGCCTGCGGTTTGAGCACCTACCGCAAGGGGTGGATCGCTCT
GCGCAACGGCAATCTCAACATCAACGCCCTCATGAGTATCGCCGTCACCGGCGCCGTGCTCATCGGCCAATGGCCCGAAG
CTGCGATGGTGATGTTTCTGTTCAATGTCGCGGAACTGATCGAGGCCCGCGCGCTCGACCGTGCCCGTAAGGCCGTGCGC
GGCCTCATGGATCTGGCGCCGCAAACCGCGCATCGCCAAAACAGCGATGGTAGCTGGAGCGACGTGCCTGCCACGCAATT
GCGCATCGGTGACGCGATTCGAGTGCGTCCTGGAGAGCGCATCGCCGCCGACGGCGAAATCTACGACGGCAGCTCCTCTA
TTGATCAGGCTCCCATCACCGGCGAAAGCCTTCCGGTGGAAAAAACCATCGGGGATGCCGTTTACGCCGGAACCATCAAC
ACCTCGGGCGCATTCGACTATCGCGTCACAGCCGCTGCCGGCAACTCCACGCTAGACCGCATCATCCACGCCGTTGAACA
GGCCCAGGGCGCCCGGGCGCCAACACAGCGTTTTATCGACCGCTTCTCACGCATCTACACCCCGGCTGTCGTACTGCTGG
CCATCCTGGTTGCGGTGGTGCCGCCACTGGCGCTAGGTCACACCTGGATGGACTCCATCTATCGCGCCCTGGCGCTGCTC
ATCATCGCCTGCCCCTGCGCGCTGGTGATTTCTACGCCCGTGAGCGTCGTCAGCGGCCTGACCGCAGCAGCCCGGCGCGG
CATTCTCATCAAAGGCGGCGTCTACCTGGAAAACGGCCGCAAACTGCGCTGGCTGGCGCTGGACAAAACCGGCACCCTGA
CACAGGGTAAGCCGGTGCAAACCGACCTCGTCGTGCTCGAACCCATCGCGGCCAATGGCCAGCCCAGCGCACAGGTCGCC
GCCAGCCTTGCGGCGCGCTCCGACCACCCTGTTTCGCGCGCCATGGCCCAGGCCAGCGCAAGCCAGGACTTCCTCACCGT
GAACGACTTTCACGCCCTGGCTGGCCGTGGCGTGGCGGGCACGATTGACGGCACCACCTACCACCTGGGCAACCGCCGTC
TGATGCGTGAACTCGGTGTGCTGACCCCGGACATCGAGGCGAGCATCGACGCCTACGAACAGCTCGGCAAAACCGCCAAC
GCGCTCAGCGATGGCCAAGGCATACTGCTGCTGGCCGCCGTCGCCGACACCCTTAAACCCAGCAGCGCCGCCGCCATCAC
AGATCTGCATGCCCTGGGTGTGCAGACCCTGATGCTCACCGGCGACAACAACCGGGCGGCTCAGGCCGTCGCGGCCCAGG
CGGGCATCGATGAGGCGCACGGCGATCTGCTGCCCGAAGACAAATTGACGCGTGTCGCCGCCAAAACCAATCAGGGCGGT
CTGGTCGGCATGGTCGGAGACGGCATCAACGACGCCCCTGCGCTAGCCCGGGCCGATATCGGCTTTGCCATGGGCGCGGC
TGGCACAGGCACCGCCATCGAAACTGCCGACGTCGCGCTCATGGACGATGACTTGCGCAAGATAGGCATTTTCGTACGCC
TGTCACGCGCCACCCACCGCGTGCTGACGCAAAATATCGTACTGGCGCTGGGCATCAAAATCGTATTCCTGACGCTCGCG
GTCACCGGCAACGCCACGCTTTGGATGGCCGTCTTCGCCGATGTCGGCGCCAGCCTGCTGGTCGTAGCCAATGGTCTTCG
CTTGTTGCGCGCTGCGCAATAG

Protein sequence :
MSKHQLSTPGTCCAPGQRPDARGDAHEHEPAHSHDGDGCCASAASQPKQSGSQLNAGSGQTLTRLRIGQMDCPTEETLIR
KKLGSMAEVQAMEFNLMQRMLTVVHSDGTLERILDAIRSLGMTPETTTSAPPSQKAGWRLLALGGVLAGLSEAAHFAGQH
PWLTALLSLAAIAACGLSTYRKGWIALRNGNLNINALMSIAVTGAVLIGQWPEAAMVMFLFNVAELIEARALDRARKAVR
GLMDLAPQTAHRQNSDGSWSDVPATQLRIGDAIRVRPGERIAADGEIYDGSSSIDQAPITGESLPVEKTIGDAVYAGTIN
TSGAFDYRVTAAAGNSTLDRIIHAVEQAQGARAPTQRFIDRFSRIYTPAVVLLAILVAVVPPLALGHTWMDSIYRALALL
IIACPCALVISTPVSVVSGLTAAARRGILIKGGVYLENGRKLRWLALDKTGTLTQGKPVQTDLVVLEPIAANGQPSAQVA
ASLAARSDHPVSRAMAQASASQDFLTVNDFHALAGRGVAGTIDGTTYHLGNRRLMRELGVLTPDIEASIDAYEQLGKTAN
ALSDGQGILLLAAVADTLKPSSAAAITDLHALGVQTLMLTGDNNRAAQAVAAQAGIDEAHGDLLPEDKLTRVAAKTNQGG
LVGMVGDGINDAPALARADIGFAMGAAGTGTAIETADVALMDDDLRKIGIFVRLSRATHRVLTQNIVLALGIKIVFLTLA
VTGNATLWMAVFADVGASLLVVANGLRLLRAAQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 2e-168 62
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 4e-99 45
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 3e-99 45
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 8e-96 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA YP_786152.1 cadmium-transporting ATPase BAC0298 Protein 5e-170 62
cadA YP_786152.1 cadmium-transporting ATPase BAC0461 Protein 6e-68 43