Gene Information

Name : guaA (BAV1568)
Accession : YP_786092.1
Strain : Bordetella avium 197N
Genome accession: NC_010645
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1632200 - 1633792 bp
Length : 1593 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCACCAGCGCATCCTCATTCTCGACTACGGTTCGCAAGTCACCCAGCTCATCGCCCGCCGCGTCCGCGAAGCTGGCGT
CTACTCTGAAATCCACCCCGGCGACGTCGACGACGCTTTCATCCGCGAGCAAGCCGCTCAGGGCCTCAAAGGCGTCATCC
TTTCCGGCAGCCACGCCTCGGCCTACGAAGAAGGCTCCATGCGCGTGCCCGCCGCCGTCTTCGAACTCGGCCTGCCCGTG
CTTGGCATCTGCTACGGCATGCAAGCCATGGCCCTGCAACTGGGCGGCAAAGTCAGCTTCAGCGATCACCGCGAATTCGG
CTACGCCGAAATCGTCGCTCAAGGCGGCACCAAGCTGCTCTCCGGCCTGGCCGACTTCCAGAACGACGCCGGCCAGGATG
TCCTCAAAGTCTGGATGAGCCACGGCGACAAAGTCACCGAACTGCCGCCCGGCTTCAGCCTCATGGCTTCCACGCCGTCC
TGCCCCATCGCCGCGATGGCCGACGAAAGCCGTGGCTATTACGCCGTGCAATTCCACCCCGAAGTCACCCACACCGTGCA
AGGCAAAGCCTTGTTCTCGCGCTTCGTGCGCGAGATCTGCGGTTGCGAAGGCGACTGGAACATGCCCGACTACATCTCCG
AAGCCGTCGCCCGCATCCGCGAGCAGGTCGGCAACGATGAGGTCATCCTCGGCCTGTCCGGCGGCGTGGACTCCTCCGTG
GCCGCAGCGCTTATCCATCGCGCCATCGGCGACCAGCTCACCTGCGTCTTCGTCGACCATGGCCTGCTGCGCCTGAACGA
AGGCCTGCAAGTCATGCAGACCTTCTCGGAAAACATGGGCGTGAAAATCATTCACGTCGATGCCACCGAGCAATTCATGG
GCAAACTGGCCGGCGTCGCCGACCCCGAAGCCAAGCGCAAAATCATCGGCCGCGAATTCGTCGAAGTCTTCCAGACCGAA
GCAGGCAAGCTCCAGGGCGCCAAATGGCTCGCCCAGGGCACCATCTACCCCGACGTCATCGAATCCGCCGGCGCCAAAAC
CGGCAAGGCCGCCGCGATCAAATCGCACCACAACGTCGGCGGTCTGCCTGAAACCCTCAACCTGCAACTGCTCGAGCCGC
TGCGCGAACTCTTCAAAGACGAAGTGCGCGAACTCGGCGTCGCCCTCGGCCTGCCGCCCCAGATGGTTTACCGCCATCCC
TTCCCCGGCCCCGGCCTGGGTGTGCGCATCCTCGGCGAAGTCAAACACGAATACGCCGAACTCCTGCGCCGCGCCGACGC
CATCTTCATCGAAGAACTGCGCAACACCAAAGACCCCGCCAGCGACCTCAGTTGGTACGACCTGACCTCCCAGGCCTTCG
CCGTCTTCCTGCCGGTCAAGTCCGTGGGCGTCATGGGCGATGGCCGCACCTACGAATACGTCGTCGCCCTGCGCGCCGTG
CAAACCTTCGACTTCATGACCGCCGACTGGGCCCCGCTGCCGCACCCCCTGCTGGCCAAGGTGTCCTCACGCATCATCAA
CGAAGTCCGCGGCATCAACCGGGTCGTCTACGACGTCTCCAGCAAACCGCCAGCGACTATCGAGTGGGAGTGA

Protein sequence :
MHQRILILDYGSQVTQLIARRVREAGVYSEIHPGDVDDAFIREQAAQGLKGVILSGSHASAYEEGSMRVPAAVFELGLPV
LGICYGMQAMALQLGGKVSFSDHREFGYAEIVAQGGTKLLSGLADFQNDAGQDVLKVWMSHGDKVTELPPGFSLMASTPS
CPIAAMADESRGYYAVQFHPEVTHTVQGKALFSRFVREICGCEGDWNMPDYISEAVARIREQVGNDEVILGLSGGVDSSV
AAALIHRAIGDQLTCVFVDHGLLRLNEGLQVMQTFSENMGVKIIHVDATEQFMGKLAGVADPEAKRKIIGREFVEVFQTE
AGKLQGAKWLAQGTIYPDVIESAGAKTGKAAAIKSHHNVGGLPETLNLQLLEPLRELFKDEVRELGVALGLPPQMVYRHP
FPGPGLGVRILGEVKHEYAELLRRADAIFIEELRNTKDPASDLSWYDLTSQAFAVFLPVKSVGVMGDGRTYEYVVALRAV
QTFDFMTADWAPLPHPLLAKVSSRIINEVRGINRVVYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-121 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-121 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-121 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-102 49