Gene Information

Name : lysS (BAV1517)
Accession : YP_786043.1
Strain : Bordetella avium 197N
Genome accession: NC_010645
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 1568873 - 1570387 bp
Length : 1515 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGACTGATCACTTGCCCACCGCCCAGGATGAAAACCGCTTGATCGCCGAAAGGCGCGCCAAGCTGGCCAAACTGCGCGA
AGCGGGTGTCGCGTACCCGAACGACTTCGTTCCGGACGCGCGCGCCGCGCAGCTGCACGACAAATACGACGACCAGGACC
CGCAAGCTCTGGTCGATGCCGCCGTGCGCGTCAAGGTGGCTGGGCGAATGATGCTCAAACGCGTGATGGGCAAAGCTAGC
TTCGCCACCCTGCAAGACGGCAGTGGCCGCATCCAGCTTTACCTGGAACGCGGCTCGCTGGGCGAAGAGGTCTATGCGGC
CTTTAAGCAATGGGATATCGGTGACATCATCGCCATCGAAGGCACGATGTTCAAGACCAACAAGGGCGAGCTCTCGGTGC
ATGCCACCAGCGCCCGCTTGCTGTCGAAGTCGCTGCGCCCGCTCCCCGATAAATTCCATGGTGTGTCCGACCAGGAATTG
CGCTACCGCCAGCGCTACGTCGATCTCATCATGACCGACTCCACGCGCCGCACCTTCGAAGCGCGCAGCAAGGCCATCGG
CGGCATCCGCCAGGCCATGCTGGCTGCCGACTTCCTGGAAGTCGAAACGCCCATGCTGCACCCGATTCCGGGCGGCGCCG
CGGCCAAGCCATTCGTCACCCATCACAATGCGCTGGACATGGAAATGTACCTGCGCATCGCGCCCGAGCTTTATCTCAAG
CGCCTGGTCGTCGGTGGCTTTGACCGCGTGTTCGAGATCAACCGCAACTTCCGCAACGAAGGGGTAAGCCCGCGCCACAA
CCCTGAGTTCACCATGATGGAGTTCTACGCCGCCTATGCGGAGTATCGCTGGATCATGGACTTCACCGAAAGCCTGATCC
GCCAGGCGGCCATCACCGCCACGGGCAGCGCCGTACTGACCTATCAAGAGCGCGAACTCGATCTGTCCAAGCCGTTCGCG
CGCCTGACGATCTGCGAAGCCATTCTCAAACATGCCCCGCATTACAGCCAGCCCCAACTCGACGACGCGGACTTCCTGCG
CGCCGAACTGAAGAAATTTGGCGCCGACGTCAACGGCCCGGTGCTCGCACGCGCCGGTGTGGGTGCTCTGCAACTCGCCC
TGTTCGAAGAAACGGCCGAGTCCAAACTCTGGGAGCCGACCTTTATCGTCGATTACCCGGTCGAAGTCTCGCCGCTGGCT
CGCGCCTCCGACACGCGCGAAGGCATCACCGAGCGCTTTGAGCTCTTCATCACGGGCCGTGAAATCGCCAACGGCTTCTC
CGAACTGAACGATCCCGAAGACCAAGCGGCACGCTTTCAGGCCCAGGTCGAAGCCAAAGACGCAGGCGACGAAGAAGCCA
TGTATTTCGATGCCGACTATATCCGCGCATTGGAATACGGCATGCCCCCCACGGGCGGCTGCGGCATCGGCATCGATCGT
CTGGTGATGCTGCTGACCGACAGCCCCAGCATCCGCGACGTGATTCTGTTCCCGCACCTGCGCCGCGAAGACTGA

Protein sequence :
MTDHLPTAQDENRLIAERRAKLAKLREAGVAYPNDFVPDARAAQLHDKYDDQDPQALVDAAVRVKVAGRMMLKRVMGKAS
FATLQDGSGRIQLYLERGSLGEEVYAAFKQWDIGDIIAIEGTMFKTNKGELSVHATSARLLSKSLRPLPDKFHGVSDQEL
RYRQRYVDLIMTDSTRRTFEARSKAIGGIRQAMLAADFLEVETPMLHPIPGGAAAKPFVTHHNALDMEMYLRIAPELYLK
RLVVGGFDRVFEINRNFRNEGVSPRHNPEFTMMEFYAAYAEYRWIMDFTESLIRQAAITATGSAVLTYQERELDLSKPFA
RLTICEAILKHAPHYSQPQLDDADFLRAELKKFGADVNGPVLARAGVGALQLALFEETAESKLWEPTFIVDYPVEVSPLA
RASDTREGITERFELFITGREIANGFSELNDPEDQAARFQAQVEAKDAGDEEAMYFDADYIRALEYGMPPTGGCGIGIDR
LVMLLTDSPSIRDVILFPHLRRED

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 3e-132 55
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 6e-82 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_786043.1 lysyl-tRNA synthetase VFG1668 Protein 2e-132 55