Gene Information

Name : YPTS_2050 (YPTS_2050)
Accession : YP_001872473.1
Strain : Yersinia pseudotuberculosis PB1/+
Genome accession: NC_010634
Putative virulence/resistance : Virulence
Product : two component heavy metal response transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 2267452 - 2268144 bp
Length : 693 bp
Strand : -
Note : TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: yps:YPTB1993 transcriptional activator

DNA sequence : 
ATGCGGCTATTGTTGGTAGAAGATGAGGAGAAGACATCTTCGTATATCAATCGCGCCCTCAGCGAGTTGGGCTTTACCGT
CGATGTGGCGGCCACCGGGAACGACGGATTATATCTGGCTCTTGAGTATGATTACGATACGATTGTGCTCGATGTCATGT
TGCCCGGCATGGATGGTTACAGCGTTCTCGAAGGCCTACGCGCCAGCAAACAAACTCCGGTTCTGATGTTATCCGCCCGT
GGCTCGGTTGATGAACGAGTTAAGGGCCTGCGTCACGGTGCCGACGATTATTTGCCTAAGCCTTTTTCGCTGATTGAACT
GGTTGCGCGTATCCAGGCGTTGTTGAGGCGGCGTCCCAGTGATGGTGTAGATGTCAGCCAATTGCACATTAATGATCTAC
ATCTCGACCTGCTGGCAAGGCGTGTCACGCGAGCCGGTGAACGTCTTGAACTCACCGCCAAAGAGTTCGCCCTGTTAAGC
CTGTTAGCCAGACATCAGGGAGAAATTCTGTCAAAAATGATGATTGCAGAGCAGGTCTGGGACATGAATTTTGACAGCGA
TGCTAATGTCGTTGAGGTGGCGATAAAACGCCTGCGGGCGAAAATAGATACGCCCTACCCGGTCAAACTGCTGCATACAG
TGCGAGGCATGGGGTATGTCCTTGAAACTCGCCCCGATCGCCAGACTAAATAG

Protein sequence : 
MRLLLVEDEEKTSSYINRALSELGFTVDVAATGNDGLYLALEYDYDTIVLDVMLPGMDGYSVLEGLRASKQTPVLMLSAR
GSVDERVKGLRHGADDYLPKPFSLIELVARIQALLRRRPSDGVDVSQLHINDLHLDLLARRVTRAGERLELTAKEFALLS
LLARHQGEILSKMMIAEQVWDMNFDSDANVVEVAIKRLRAKIDTPYPVKLLHTVRGMGYVLETRPDRQTK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 4e-54 50
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 7e-53 49

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
YPTS_2050 YP_001872473.1 two component heavy metal response transcriptional regulator BAC0083 Protein 1e-62 61
YPTS_2050 YP_001872473.1 two component heavy metal response transcriptional regulator BAC0197 Protein 2e-59 58
YPTS_2050 YP_001872473.1 two component heavy metal response transcriptional regulator BAC0638 Protein 3e-53 57
YPTS_2050 YP_001872473.1 two component heavy metal response transcriptional regulator BAC0125 Protein 3e-61 56
YPTS_2050 YP_001872473.1 two component heavy metal response transcriptional regulator BAC0111 Protein 4e-59 54
YPTS_2050 YP_001872473.1 two component heavy metal response transcriptional regulator BAC0347 Protein 3e-52 51
YPTS_2050 YP_001872473.1 two component heavy metal response transcriptional regulator BAC0308 Protein 1e-52 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
YPTS_2050 YP_001872473.1 two component heavy metal response transcriptional regulator VFG0596 Protein 2e-54 50
YPTS_2050 YP_001872473.1 two component heavy metal response transcriptional regulator VFG1389 Protein 2e-38 48
YPTS_2050 YP_001872473.1 two component heavy metal response transcriptional regulator VFG1390 Protein 1e-39 44
YPTS_2050 YP_001872473.1 two component heavy metal response transcriptional regulator VFG1386 Protein 4e-35 43