Gene Information

Name : leuS (Npun_F4156)
Accession : YP_001867477.1
Strain : Nostoc punctiforme PCC 73102
Genome accession: NC_010628
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 5218412 - 5221027 bp
Length : 2616 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
GTGGATTCCCGATATAACCCAGCAGCGATTGAGGAAAAACGGCAGAAAACATGGTTAGAACTTGGCTTAGATAAAACACC
TTCAGCTAGCAACAAGCCAAAATTCTACGCTTTATCCATGTTCCCTTATCCATCGGGCAGCCTACACATGGGTCACGTCC
GTAATTATACCATTACTGACGTGATTGCCCGCTTCAAGCGAATGCAAGGGTATCGGGTAATACACCCAATGGGTTGGGAT
GCCTTTGGCTTGCCAGCAGAAAATGCCGCTATTGACCGTGGTGTACCGCCAGCAAAGTGGACTTATCAGAATATTACCCA
GATGCGGCAGCAATTACAGCGTCTTGGTTTATCAATTGATTGGGAATGTGAATTAGCTACTTGTTCACCAGATTATTACA
AGTGGACACAATGGATTTTCTTGCAGTTTTTGCAAGCAGGGTTAGCTTACCAAAAAGAAGCAGCCGTAAACTGGGACCCC
ATTGACCAAACTGTATTAGCAAATGAGCAAGTTGATAACGAAGGACGTTCCTGGCGCAGTGGCGCAATAGTTGAGCGCAA
ATTGTTGCGGCAGTGGTTTTTTAAGATTACCGACTACGCCGAAGAATTACTCAATGACTTGGATAAGTTGACAGGTTGGC
CGGAACGGGTCAAATTGATGCAGGCAAACTGGATTGGTAAATCCACAGGCGCTTATTTAGAATTTCCCATTGTTGGGATA
GATGAAAAAATCGCTGTGTATACCACGCGCCCAGATACAGTTTATGGTGTCAGTTATTTAGTATTAGCACCAGAACATCC
TTTAACAAATCGCGTTACCACAAAAGAACAACAAGCGGCGGTAGAAGTCTTTATTAAAGAGGTTTCTAATCAAAGTGAGT
TGGAACGTACTTCTGAAGACAAACCTAAGCGGGGTATCCCTACCGGTGGTGTGGCAATTAACCCGTTTACAGGGGAAGAA
GTGCCTATTTGGATTGCTGACTATGTACTGTATGAGTATGGTACTGGGGCGGTGATGGGTGTACCCGCACACGATGTCCG
GGATTTTAAGTTTGCTAAAAATTACGATTTACCAATTAATTTTGTCATCGCTTCCCCAGATGATGTTGCAGGTTTTGACT
TAACTCCAACATCAGAGATTGATGGAATCACACAACTTGTTGAAGTTGACTATAAGCAGGCATACACTGAACCAGGAATT
TTAATTAATTCTGGGGCTTTTACTGGTATATCTTCCACAGATGCTAAACAAGCCATAATTGAATACGCCGAAAAACAAGA
TTTTGGTAAAGTGCGAGTGCAATATCGCTTGCGGGATTGGTTAATTTCCCGGCAGCGTTACTGGGGCGCACCGATACCTG
TAATTCACTGTCCCAACTGTGGGATAGTGCCAGTGCCTGACAAAGATTTACCAGTCCAGTTGCCAGAAGAGGTGGAATTT
ACTGGACGTTGCGGTTCACCTTTGACTCAGTTGGAAAGCTGGGTAAATGTGCCTTGTCCAACTTGCGGCACTCCAGCGAA
GCGCGAAACTGACACGATGGACACTTTTATTGATTCCTCGTGGTATTTCTTGCGCTTCCCTGACGCTAAAAATGAACAAC
AGGTTTTCGATTCCAGTAAAGTAAACGACTGGATGCCAGTGAATCAGTACGTGGGTGGGATTGAACACGCGATTCTACAT
TTGTTGTATTCGCGGTTCTTTACTAAAGTACTCCGGGACAGAGGGTTACTGAACTTTGATGAACCTTTCCAACGTCTGTT
AACTCAAGGGATGGTACAGGGTTTAACTTACCTAAATCCCAATAAGGGCGGTAAAGATAAATGGATTCCTTCTAATCTGG
TCAATTCTGCTGACCCCCGCGACCCTCAGACAGACGAACCTTTGCAACGTCTCTACGCCACCATGTCTAAATCAAAGGGC
AACGGTGTCGCGCCAGAAGATGTAATTTCCAAATATGGTATAGACACAGCAAGGATGTTCATCTTGTTCAAAGCACCACC
AGAAAAAGACCTGGAATGGGATGAAGCCGATGTGGAAGGACAATTCCGCTTTTTAAATCGGGTTTGGCGTTTGGTGACGG
ATTATATTACTGCTGGGGTATCCCGTAAGAAAGCCCAATCTGATTTAACTAAGGCTGAAAAGGAATTGCGGCGGGCGATT
CACACGGCTATTCAAGCGGTGACGGAAGATGTGGAAGACGAATATCAATTCAACACAGCTATTTCCGAATTGATGAAGTT
GAGTAATGCCCTAAGTGATGCTGACAAAAATTCACCAATTTACGCAGAAGGTATTCGGACTTTGGTGATATTAATCGCAC
CCTTTGCACCACATATTGCTGATGAATTGTGGCATTTGTTGGGTGAAAGTGATTCAATTCACACTCAAACTTGGCCATCA
TTTGACCCTGCTGCTTTAGTAGCTGATGAAATCACTTTAGTGATTCAAGTTATGGGTAAAACTCGCGGCGCGATTCAAGT
ACCAGCACAAGCAGATAAAGCAGCGTTGGAGAAATACGCCCGTGAATCAGAAATTGCCCAGCGTTACATCGAAGGCAAAG
AGATTAAAAAGGTAATTGTAGTGCCTGGCAAGTTAGTGAATTTTGTAGTCAGCTAA

Protein sequence :
MDSRYNPAAIEEKRQKTWLELGLDKTPSASNKPKFYALSMFPYPSGSLHMGHVRNYTITDVIARFKRMQGYRVIHPMGWD
AFGLPAENAAIDRGVPPAKWTYQNITQMRQQLQRLGLSIDWECELATCSPDYYKWTQWIFLQFLQAGLAYQKEAAVNWDP
IDQTVLANEQVDNEGRSWRSGAIVERKLLRQWFFKITDYAEELLNDLDKLTGWPERVKLMQANWIGKSTGAYLEFPIVGI
DEKIAVYTTRPDTVYGVSYLVLAPEHPLTNRVTTKEQQAAVEVFIKEVSNQSELERTSEDKPKRGIPTGGVAINPFTGEE
VPIWIADYVLYEYGTGAVMGVPAHDVRDFKFAKNYDLPINFVIASPDDVAGFDLTPTSEIDGITQLVEVDYKQAYTEPGI
LINSGAFTGISSTDAKQAIIEYAEKQDFGKVRVQYRLRDWLISRQRYWGAPIPVIHCPNCGIVPVPDKDLPVQLPEEVEF
TGRCGSPLTQLESWVNVPCPTCGTPAKRETDTMDTFIDSSWYFLRFPDAKNEQQVFDSSKVNDWMPVNQYVGGIEHAILH
LLYSRFFTKVLRDRGLLNFDEPFQRLLTQGMVQGLTYLNPNKGGKDKWIPSNLVNSADPRDPQTDEPLQRLYATMSKSKG
NGVAPEDVISKYGIDTARMFILFKAPPEKDLEWDEADVEGQFRFLNRVWRLVTDYITAGVSRKKAQSDLTKAEKELRRAI
HTAIQAVTEDVEDEYQFNTAISELMKLSNALSDADKNSPIYAEGIRTLVILIAPFAPHIADELWHLLGESDSIHTQTWPS
FDPAALVADEITLVIQVMGKTRGAIQVPAQADKAALEKYARESEIAQRYIEGKEIKKVIVVPGKLVNFVVS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 4e-170 44