Gene Information

Name : hemC (Npun_F3798)
Accession : YP_001867125.1
Strain : Nostoc punctiforme PCC 73102
Genome accession: NC_010628
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 4794051 - 4795061 bp
Length : 1011 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAGAGTGAATTTATCGCCTTGTTTGATATATTGTTTTATGACTTCAGTTGTTTCTAGTCCCCCACGCACTATTCGGAT
CGGTTCACGCAAAAGCCAACTTGCTCTAGTTCAAACCTATTGGGTACAAGAGCAACTCCAAAAAAGCTTTCCTGATATCA
CTTTTGAAGTCCATACCATGTCTACCCAAGGCGACAAAATCCTTGATGTAGCATTAGCTAAGATTGGCGATAAAGGACTT
TTTACTAAAGAACTTGAAGTTGGAATGCTCAATCAAGAGATTGACTTTGCGGTTCATTCTCTCAAGGATTTGCCGACTAA
CTTACCAGAAGGATTGACACTGGCAGCAATTACTGAACGGGAAAATCCAGCCGATGCCTTGGTTGTGCATGAAAAGCACA
AAGATAAACAAATCGATACTTTACCCGAAGGTGCAGTAATTGGGACATCTTCGCTGCGGCGGTTAGCACAGTTACGCCAC
CACTTCCCCCACTTTACTTTTAAAGATGTGCGGGGAAACTTGATTACACGATTGGCAAAACTGGATGCAGGCGAATACGA
TGCCTTAATTTTGGCAGCCGCAGGGTTAGAAAGATTGGGAATGAGCGATCGCGTTCATCAAATTATCCCCAAAGAAATCT
CCCTCCATGCCGTTGGACAAGGTGCTTTAGGGATAGAATGCCGTGCTGATGATAGTGAATTGCTAACTCTACTCAAAGCA
ATCGAACATCCTGCAACACGCGATCGCTGTCTCGCCGAACGTTCTTTTCTACGCTCTTTAGAGGGCGGATGTCAAGTACC
TATTGGTGTAAATACAGAAATCTCTGGTGAGAATTTGACCTTAACAGGCATAGTTGCCAGTATAGATGGTCAAAAGTTGG
TAAAAGATACCGTCACTGGAATTGCCAATAATGCCGAAGCGCTAGGCACAGAACTAGCAGAATTATTGCGGCAACAGGGA
GCGCAAGAAATTTTATCAGAAATTTTTGCGGTCATTCAACGCGGTTCCTAA

Protein sequence :
MRVNLSPCLIYCFMTSVVSSPPRTIRIGSRKSQLALVQTYWVQEQLQKSFPDITFEVHTMSTQGDKILDVALAKIGDKGL
FTKELEVGMLNQEIDFAVHSLKDLPTNLPEGLTLAAITERENPADALVVHEKHKDKQIDTLPEGAVIGTSSLRRLAQLRH
HFPHFTFKDVRGNLITRLAKLDAGEYDALILAAAGLERLGMSDRVHQIIPKEISLHAVGQGALGIECRADDSELLTLLKA
IEHPATRDRCLAERSFLRSLEGGCQVPIGVNTEISGENLTLTGIVASIDGQKLVKDTVTGIANNAEALGTELAELLRQQG
AQEILSEIFAVIQRGS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-59 52
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-59 52