Gene Information

Name : alr (Bphy_1359)
Accession : YP_001857587.1
Strain :
Genome accession: NC_010622
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : 5.1.1.1
Position : 1526499 - 1527590 bp
Length : 1092 bp
Strand : -
Note : converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer

DNA sequence :
ATGTCTTTACGAAAATATCCCATGCCGCGCCCAGTCTCAGCCACGATTCACACTGCCGCTCTCGCCAATAATCTCGCTGT
CGCCCGTCGCTACGCGCCGAAGTCCAAGATCTGGGCTGTCGTCAAGGCCAATGCGTACGGTCACGGACTCGCGCGGGCAT
TCCCAGGCTTGCGCGCAACCGACGGCTTTGGTTTGCTCGACCTCGAAGAAGCGGTGAAGTTGCGTGAATTGGGGTGGGCG
GGGCCGATTTTGTTGCTGGAGGGCTTTTTCCGGCCCACCGATATCGACGTCATCGACCGTTATAGTCTGACCACGGCGCT
GCATTCGGACGAGCAGTTGCGCATGCTGGAAATGGCGCGCCTGTCCAAGCCCGTCAATATCCAGTTAAAGATGAACAGCG
GCATGAACCGCCTCGGCTATACGCCGGAGAAGTTCCGTGCAGCCTGGGAACGTGCGCGGGCCTGCCAGGGCGTCGGCCAG
ATCACGTTGATGACCCATTTCTCGGATGCCGACAGCGAGCGCGGCATCTCGCATCAGATGGAAGCATTCGAGCGTGGCGC
ACAGGGCATTGCGGGCGCGCGCAGCCTCGCCAATTCGGCCGCCACGCTGTGGTATCCGGAAGCGCATTTCGACTGGGTGC
GCCCGGGCGTGATGCTGTACGGCGCGTCGCCGTCGGGCGTAAGCTCGGCGATCAAGGACACGGGCCTGCAGCCGGCCATG
ACGCTTGCTTCGGAACTCATCGCCGTGCAGACGCTCGCGCAAGGGCAGACGATCGGCTATGGCTCGACCTTCACGGCGCG
CGAAGGCATGCGCATCGGCGTGGTCGCGTGCGGCTATGCGGACGGTTATCCGCGCGTCGCGCCGGAGGGTACGCCCATCA
TCGTCGACGGCATCCGTACGCGCATCGTCGGTCGTGTGTCGATGGACATGATCACCGTCGATCTCACGCCTTGCCCGCAG
GCGAACGTCGGCTCGCGTGTGGAGCTGTGGGGCGCCCAACTGCCCGTCGATGACGTCGCGCAGTCGTGCGGCACGATCGG
CTACGAGCTTGTGTGCGCCGTCGCGCCGCGCGTGCCCGTACGAGCCGAGTGA

Protein sequence :
MSLRKYPMPRPVSATIHTAALANNLAVARRYAPKSKIWAVVKANAYGHGLARAFPGLRATDGFGLLDLEEAVKLRELGWA
GPILLLEGFFRPTDIDVIDRYSLTTALHSDEQLRMLEMARLSKPVNIQLKMNSGMNRLGYTPEKFRAAWERARACQGVGQ
ITLMTHFSDADSERGISHQMEAFERGAQGIAGARSLANSAATLWYPEAHFDWVRPGVMLYGASPSGVSSAIKDTGLQPAM
TLASELIAVQTLAQGQTIGYGSTFTAREGMRIGVVACGYADGYPRVAPEGTPIIVDGIRTRIVGRVSMDMITVDLTPCPQ
ANVGSRVELWGAQLPVDDVAQSCGTIGYELVCAVAPRVPVRAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 3e-96 57