Gene Information

Name : guaA (KRH_06820)
Accession : YP_001854535.1
Strain : Kocuria rhizophila DC2201
Genome accession: NC_010617
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 740999 - 742597 bp
Length : 1599 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGACTGAAACCCCTGACAACCTGAGCGAACTGGAGCAACGCCCGGTACTCGTGGTCGACTACGGTGCGCAGTACGCGCA
GCTGATCGCCCGCAGGGTGCGCGAGGCCAACGTGTACTCCGAGATCGTCCCGCACACCTGGTCCACGGAGCAGATCCTGC
AGCGCAACCCCGCTGCCCTGATCCTCTCCGGCGGCCCCGCCTCCGTGTACGCGCCCGGCGCGCCGCAGCGCGATGCCGAG
CTGTTCGAGGCCGGCGTGCCCGTGCTGGGCATCTGCTACGGGTTCCAGGTCATGGCCGCCGCCCTGGGCGGGACCGTGGA
GCGCACGGGGGTGCGCGAGTACGGCGCCACCACCGCCACGTGCCAGGACACCGCCGTGGGCACCCTGCTGGACGGCACCC
CGGACGTGCAGACCGTGTGGATGAGCCACGGTGACTCCGTCACGGCCGCCCCCGAGGGCTTCACCACCCTGGCCACCACC
GAGGGTGCCCCCGTGGCGGCCTTCGAGAACCGCGAACGCCGCCTCTACGGCGTGCAGTGGCACCCCGAGGTCAAGCACTC
GGCGTACGGGCAGAAGATCTTGGAGAACTTCCTCTTCAACGGCGCCCAGCTGAGCCCCACGTGGTCCACCGGCAACATCA
TCGAGGAGCAGGTGGCCGCGATCCGCGCCCAGGTGGGTGACGGCAAGGCCCTGTGCGGGCTCTCCGGCGGCGTGGACTCC
GCCGTGGCCGCGGCCCTCGTGCAGCGCGCCATCGGCGACCGCCTCACGTGCGTGCTCGTGGACCACGGGCTGATGCGCCA
GGACGAGGTCGAGCAGGTCGAGAAGGACTACGTGGCCGCCACGGGCGTCAAGCTGCACGTGGCTCGGGAGCAGGACCGCT
TCCTGGAGGCCCTCAAGGGAGTCACCGACCCCGAGACCAAGCGCAAGGCCATCGGCCGGGAGTTCATCCGCGCGTTCGAG
GCCGCCGAGGAGAAGGTGCTTCGCGCCGAGGCCCAGGACGGCGAACCCGTGCGGTTCCTGGTCCAGGGCACCCTCTACCC
GGACGTCGTCGAGTCGGGCGGTGGTGAGGGCGCGGCCAACATCAAGAGCCACCACAACGTGGGCGGCCTGCCCGAGGACC
TGCAGTTCGAGCTCGTGGAGCCGCTGCGGGCCCTGTTCAAGGACGAGGTCCGCGCGGTGGGCCGCGAGCTCGGGCTGCCC
GAGAACATCGTGGGCCGCCAGCCGTTCCCCGGCCCCGGCCTGGGCATCCGCATCATCGGCGAGGTCACCGAGCACCGCCT
GGACATCCTGCGCCGCGCGGACGCGATCGCGCGCGAGGAGCTCACCAGGGCGGGTCTGGACGACGAGGTCTGGCAGATGC
CCGTGGTGCTGCTCGCGGATGTGCGCTCCGTGGGCGTGCAGGGCGACGGCCGCACCTACGGTCACCCGATCGTGCTGCGA
CCGGTCAGCTCCGAGGACGCCATGACCGCCGACTGGTCCCGGCTGCCCTCCGAGCTGCTGGCGCGGGTGTCCAACCGGAT
CACCAACGAGGTCGAGGAGATCAACCGCGTGGTCCTGGACGTGACGTCCAAGCCGCCGGGAACCATCGAGTGGGAGTGA

Protein sequence :
MTETPDNLSELEQRPVLVVDYGAQYAQLIARRVREANVYSEIVPHTWSTEQILQRNPAALILSGGPASVYAPGAPQRDAE
LFEAGVPVLGICYGFQVMAAALGGTVERTGVREYGATTATCQDTAVGTLLDGTPDVQTVWMSHGDSVTAAPEGFTTLATT
EGAPVAAFENRERRLYGVQWHPEVKHSAYGQKILENFLFNGAQLSPTWSTGNIIEEQVAAIRAQVGDGKALCGLSGGVDS
AVAAALVQRAIGDRLTCVLVDHGLMRQDEVEQVEKDYVAATGVKLHVAREQDRFLEALKGVTDPETKRKAIGREFIRAFE
AAEEKVLRAEAQDGEPVRFLVQGTLYPDVVESGGGEGAANIKSHHNVGGLPEDLQFELVEPLRALFKDEVRAVGRELGLP
ENIVGRQPFPGPGLGIRIIGEVTEHRLDILRRADAIAREELTRAGLDDEVWQMPVVLLADVRSVGVQGDGRTYGHPIVLR
PVSSEDAMTADWSRLPSELLARVSNRITNEVEEINRVVLDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-169 70
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-128 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-128 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-128 51