Gene Information

Name : hsdR (KRH_05260)
Accession : YP_001854379.1
Strain : Kocuria rhizophila DC2201
Genome accession: NC_010617
Putative virulence/resistance : Unknown
Product : type I restriction enzyme R protein
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0610
EC number : 3.1.21.3
Position : 572075 - 575209 bp
Length : 3135 bp
Strand : +
Note : -

DNA sequence :
ATGAACACCTTCAATGAGAACGTCGTTGAGCAGGCCGCTCTGGAGTACTTCGCCGAGCTGGGTTACCGACGTGTGCATGG
CCCTGACATCGCGCCAGGAGAGCCTGGCGCTGAGCGGGAGTCGTACGAGGACGTCATGTTGTGGGGGCATGTGCGTGATG
CGCTTCGGCGGATTAATCGTGGTGCGGACGCCGCGCTTGTCGCAGAGGCTGTGAAGACGGTTCAGCGTGCCGAGTCACAG
AGCCCAATCGACGAGAACGCTCGCCTGCATAAGCTCATCACGGAGGGCGTACCGGTCGAGCATCGCGGCGACGATGGTCT
GCTGCGCACAACGCGCTTGTGGCTCATGGACTTCGACGAGCCGGAGAACAACGACTGGGTGGCTGTCAGCCAGTTCACGA
TCGTCGAGAACGGCAAGAATCGCCGCCCTGACGTGCTCGTCATGGTCAACGGGCTCCCGCTCTCGTTGTTGGAGCTGAAG
AACCCGGCCGCTGAGCACGCGACGCTGAAGTCGGCGTGGAACCAGGTGCAGACCTACCGCCATGACATCCCGTCGGTGTT
CGTGCCCAACGCTGTCACGGTGATCTCTGACGGCACATCTGCTGCGATGAGCAGTTACTCGGGTGCGTTCGAGCACTACG
CGCCGTGGAAGACCATCGAGGGGCGTGAGGTTGTCAGCAACCGGCCAGCCCTTGAGGTTCTCATCAAGGGTGTGTTCGAG
CCGAAGCGGTTCCTGGACCTGCTGAAGAACTTCGTCGTGTTCAGTGACGAGACAGTCACCGACAAGTCGACAGGACAGCC
GACGCGGGCGCTCGTGAAGCGTGTGGCGAAGTACCACCAGTACTGGGCGGTCAACGCTGCCGTCGAGTCCACGGTGCAAG
CGTCAAGCCCTGATGGGGACCGTCGCGGCGGTGTCGTGTGGCACACGCAGGGGTCGGGAAAGAGCTTCGAGATGGTGTTC
TACGCCGCGAAGATCATGCGTGACCCGCGCATGGCGAACCCGACGCTGGTGTTCATCACTGACCGCAACGATCTCGACGA
TCAGCTGTTCGGCGAGACTTTCGCCCCCGCGCGCATCCTGCCGGAGACGCCGGTGCAGGCAGCAACGCGCTCGGATCTGC
GGGCCAAGCTGAAGCGCGCGTCGGGTGGGATCGTGTTCACCACCTTGCAGAAGTTCGCGCCGGGCGAGGACGGGGATACC
AACCCCGTGCTCACTGACCGTCGGAACGTCATCGTTATCGCCGACGAGGCGCACAGGAGTCAGTACGGCTTCAGCGAGAC
GCTCGACCGCCACGGCCGGCTCAAGTCTGGGCTGGCCAAGCACATGCGCGACGCGCTCCCTGGTGCCACGTACCTCGGTT
TCACCGGCACTCCGATCGAGTCGAAAGACAAGTCCACCCGGGCTGTGTTCGGCGACTACGTCGACGTGTACGACCTCACA
AGGGCAGTGGAGGATGGCGCGACTGTCCGGATCTTCTACGAGTCCAGGCTGGCAAAGATCGAGCTGTCGGAAGTTGACCA
CGCAGCCCTCGACGAGCTCGCCGACGAGATCACCGAGTCCGTCGAGGAAGACACGGCAACAGCTGCGAAGTCACGTTGGT
CGCGGCTGGAGGCGGTCGTCGGAGCGGAGGCACGACTTGACCTCGTAGCTCGCGACATCGTGGAGCACTGGGAGAAGCGC
CGGGAGTCCCTGTTCGGCAAGGGCATGATCGTGACCATGAGTCGCCGGATCGCTGTACGGCTGTACGAGAAGATCGTCGC
GCTGCGGCCCGATTGGCACTCGGATGACCCGGCGCAGGGCAAGATCAAGGTCGTCATGACCGGGTCCGCGTCTGATCCTG
CTGAGTTCCAGCCGCACATCCACTCGAAGGACGTGCGCAAGGACCTCAAGCTGCGGGCGAAGAACGCGGACGACCCGCTG
GAACTGGTCATCGTCCGTGACATGTGGCTGACCGGTTTCGATGCCCCGTCGATGCACACGATGTACGTCGACAAGACCAT
GCAGGGCGCCGGGCTCATGCAGGCCATCGCTCGGGTCAACAGGACGTTCCGCGACAAGCCTGGCGGGCTGATCGTCGACT
ACATCGGAGTGTTCGCGAACCTCCAGAACGCGTTGAGCGAGTACTCGCCGTCCGACCGCGAACAGGCTGGCGTGCCCATC
GACGAGATGGTCCAGGTGATGTTGGAGAAGCATGACATCGTGCGCGGGCTGCTGCACGGCGTCCAATTCGATTCTTCCCC
GGAGCTGACAGCCTCGCAGCGGTTGAACGAGTACGCGAAGGTCCTCGACTTCGTCATGGCGGACCCAGACCGGACTTCGC
GATTTAATGACCAGGTGCTGGCTCTGGCGAAGGCGTTTGCGCTGGCGGGCGCGCGCGATGAGGCAGCCGCGATCCGGAAC
AATGTCCGACTGTTCACGGACGTCAGGGCAGCGATCCTAAAGATCCAGAACCCTGACTCCGGCCGAGGCGGGTCAGGTGC
CGTAGGGATCGATACAGCGCTCGGGCAGCTACTCAACGAGGCCGTTGCGGCCGATCAAGTCGTCGACGTCTATAAGCTCG
CTGGCGTGGATACGCCAGACCTCTCAATCCTCAGCGACGAGTTCCTCAATTCGTTCGCGGAGAAGGACAAACCCAACCTC
CAAATGGGTCTGCTGCATCGGTTGCTCAACGATCAAATTCGTACGGTGCAGCGCACCAACATTGTTCAAGCACGCAAGTT
CTCCGAGCTACTGGATGAGGCGATTAACCGATACACGAACCGATCACTGACGACGGCAGAGATCATTGCGGAGCTGGTAA
AACTCGCCAAGCAAATGCGCGACGATCAGAAGCGCCACGACGACCTCGGGCTTTCTAGCGCTGAGGTCGCGCTCTATGAT
GCGATCGCGCAGAACGATTCCGCCGTGCTGGAAATGGGCGACGAAACGTTGAAGAAAATTGCTGTCGACGTGGTCTGGGC
AGTCCGCAACAGCGTTGTCATCGACTGGGATCAAAAAGAGAGTGTCCGTGCCTCGATGCGATCCAGTGTGCGCCGCATCC
TCGCAAAGTATGACTATCCTCCTGATGCTGAGGACGAGGCAGTCAACCTTGTACTGGAGCAAGCAGAGTTGTATGCCGAC
AGCGCAACGAGGTAG

Protein sequence :
MNTFNENVVEQAALEYFAELGYRRVHGPDIAPGEPGAERESYEDVMLWGHVRDALRRINRGADAALVAEAVKTVQRAESQ
SPIDENARLHKLITEGVPVEHRGDDGLLRTTRLWLMDFDEPENNDWVAVSQFTIVENGKNRRPDVLVMVNGLPLSLLELK
NPAAEHATLKSAWNQVQTYRHDIPSVFVPNAVTVISDGTSAAMSSYSGAFEHYAPWKTIEGREVVSNRPALEVLIKGVFE
PKRFLDLLKNFVVFSDETVTDKSTGQPTRALVKRVAKYHQYWAVNAAVESTVQASSPDGDRRGGVVWHTQGSGKSFEMVF
YAAKIMRDPRMANPTLVFITDRNDLDDQLFGETFAPARILPETPVQAATRSDLRAKLKRASGGIVFTTLQKFAPGEDGDT
NPVLTDRRNVIVIADEAHRSQYGFSETLDRHGRLKSGLAKHMRDALPGATYLGFTGTPIESKDKSTRAVFGDYVDVYDLT
RAVEDGATVRIFYESRLAKIELSEVDHAALDELADEITESVEEDTATAAKSRWSRLEAVVGAEARLDLVARDIVEHWEKR
RESLFGKGMIVTMSRRIAVRLYEKIVALRPDWHSDDPAQGKIKVVMTGSASDPAEFQPHIHSKDVRKDLKLRAKNADDPL
ELVIVRDMWLTGFDAPSMHTMYVDKTMQGAGLMQAIARVNRTFRDKPGGLIVDYIGVFANLQNALSEYSPSDREQAGVPI
DEMVQVMLEKHDIVRGLLHGVQFDSSPELTASQRLNEYAKVLDFVMADPDRTSRFNDQVLALAKAFALAGARDEAAAIRN
NVRLFTDVRAAILKIQNPDSGRGGSGAVGIDTALGQLLNEAVAADQVVDVYKLAGVDTPDLSILSDEFLNSFAEKDKPNL
QMGLLHRLLNDQIRTVQRTNIVQARKFSELLDEAINRYTNRSLTTAEIIAELVKLAKQMRDDQKRHDDLGLSSAEVALYD
AIAQNDSAVLEMGDETLKKIAVDVVWAVRNSVVIDWDQKESVRASMRSSVRRILAKYDYPPDAEDEAVNLVLEQAELYAD
SATR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
api52 CAF28526.1 hsdr-like Type I restriction enzyme Not tested YAPI Protein 0.0 45
hsdR BAH57699.1 type I restriction-modification system endonuclease homologue Not tested Type-VII SCCmec Protein 0.0 45
hsdR BAD24840.1 type I restriction-modification system endonuclease homologue Not tested Type-V SCCmec Protein 0.0 44
hsdR YP_251977.1 type I restriction-modification system restriction subunit Not tested SCCmec Protein 0.0 44