Gene Information

Name : hsdM (KRH_05230)
Accession : YP_001854376.1
Strain : Kocuria rhizophila DC2201
Genome accession: NC_010617
Putative virulence/resistance : Unknown
Product : type I restriction enzyme M protein
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : 2.1.1.-
Position : 568589 - 570154 bp
Length : 1566 bp
Strand : +
Note : -

DNA sequence :
ATGGCGAGACGGGCCGCGAAGACGAAGCCAGCGAAGACGCTGGAACAGACACTGTGGGATGCCGCTGACAAACTCAGGGG
CAACCAGGAGCCCAGCGAGTACAAGCATGTCGTGCTGGGTCTGGTATTCCTCAAGTACGTCTCCGACCGGTTCGAGGAGC
GCCGCGAGCAGCTCAAGGGCGAGCTGGCCGCCGAGGGCATCAAGCCCGAGCGGATCGAGTCGTTCTTGGAGGATCGCGAC
GAGTACGCGAGCCAGAACGTTTTCTGGGTACCATCCCTCGCGCGATGGGGCTACGTGCAGTCGGTGGCGAAGCAGCCTGA
GATCGGCCAGCAGATCGACCAGGCGATGGATCTCATCGAGAAGGAGAACCCCTCCCTGCGCGGCGTGCTCCCTCGCAACT
ATGGCCGGGACGGTCTCGACAAGCGCCGTCTCGGTGAGCTGGTCGATCTCATCGGTTCGATCGGCTTCACTGAGACCGAC
GATCACGGCGCAGACGATGTGCTCGGCCGCGTGTACGAGTATTTCCTGGGCCAGTTCGCGGGCAAAGAGACTGGCAAGGA
CGCCGGAGCGTTCTACACGCCACGCTCCGTCGTCCGGACGCTCGTGGAGATGCTGGAGCCCTACAAGGGTCGCGTCTATG
ACCCAGCAGCAGGCTCTGGCGGCATGTTCGTGCAGTCAGCGGAGTTCGTGAAGGCCCACGGCGGCAAGCGCACTGACATC
TCTGTGTACGGGCAGGAGTTCACCGATACCACGTGGAAACTGGCGAAGATGAACCTGGCCTTGCGGGGCATCGAGGCTGA
CATGGGCACGCACTCGGCTGATTCATTCACCGAGGATCTCCACCCAGACCTGCGCGCTGACTTCGTAATCGCGAACCCGC
CGTTCAACGTGTCTGACTGGTGGGATGCGAAGCTCGCCGACGATCCCCGATGGAAATACGGAACACCACCGAAGGGCAAC
GCGAACTTCGCATGGGTGCAACACTTCCTTCACCATCTTGCTCCCTACGGCACAGCAGGGTTCGTGCTCGCCAACGGGTC
ACTGTCTTCCAAGAGCAGTGGCGAGGGCGAGACCCGTCAGCGGCTCGTCGAGGCGGGCCTGGTCGACTGCATCGTCGCGA
TGCCCGACAAACTGTTCTTCAACACTGGCATCCCCGTGTCACTGTGGTTCGTTTCCAAGGGGCGTGACGGCAACGGGCAC
CGCGCGCGCAAAGGGGAGGTGCTGTTTATTGACGCCCGCAAGCTCGGCCGGATGGAGTCACGCAAACTGCGCGTGCTCGA
TAACGACGACATCGGGAAGATCGCGGGCACGTACCATGCGTGGCGCGACCACGACGGCGGTTACCAGAACGAGACTGGGT
TCGCGAAGGCCGCGAAGATCGAAGAAATCGAGAAGCATGACTTCGTCCTGACCCCTGGCCGCTACGTAGGTGCGGCGGAG
GCGGAGGTTGACGACGAGCCGATCGACGAGAAAATCGAGCGCCTCACGACCGAGCTATTTGCAGAATTCGAGCGCGGACG
TGAGCTTGAAGATGAGGTTCGTGCTCGACTGAGAGGTGTGCTTTGA

Protein sequence :
MARRAAKTKPAKTLEQTLWDAADKLRGNQEPSEYKHVVLGLVFLKYVSDRFEERREQLKGELAAEGIKPERIESFLEDRD
EYASQNVFWVPSLARWGYVQSVAKQPEIGQQIDQAMDLIEKENPSLRGVLPRNYGRDGLDKRRLGELVDLIGSIGFTETD
DHGADDVLGRVYEYFLGQFAGKETGKDAGAFYTPRSVVRTLVEMLEPYKGRVYDPAAGSGGMFVQSAEFVKAHGGKRTDI
SVYGQEFTDTTWKLAKMNLALRGIEADMGTHSADSFTEDLHPDLRADFVIANPPFNVSDWWDAKLADDPRWKYGTPPKGN
ANFAWVQHFLHHLAPYGTAGFVLANGSLSSKSSGEGETRQRLVEAGLVDCIVAMPDKLFFNTGIPVSLWFVSKGRDGNGH
RARKGEVLFIDARKLGRMESRKLRVLDNDDIGKIAGTYHAWRDHDGGYQNETGFAKAAKIEEIEKHDFVLTPGRYVGAAE
AEVDDEPIDEKIERLTTELFAEFERGRELEDEVRARLRGVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 1e-141 55
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 4e-141 54
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 2e-139 54
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 2e-119 50