Gene Information

Name : lysS (KRH_19180)
Accession : YP_001855771.1
Strain : Kocuria rhizophila DC2201
Genome accession: NC_010617
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 2203958 - 2205490 bp
Length : 1533 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
GTGACCGAGCAGCCTGAGACCACCGTTCCCGCCGAGCCCGCCAGCACCGATCCGGAGCTGAGCGCCCACGAGCTCAACGA
CCAGATGGCCGTGCGCGCCGCCAAGCGGCAGGCCGCCGCGGACGCCGGGATGCACCCCTACCCCGTGGGTGTGCACCGCA
CCGCGACCCTCGCGAGCGTGCGGGCGGAGTTCGGTCACCTCGCGGACGGCGAGGAGACCGACCACGTGGTCACCGTGGCC
GGTCGCGTGGTGCACGTGCGCAACACCGGCAAGCTGTGCTTCGGGACCCTCCAGGAGGGGGACGGCACCCGCCTGCAGGT
CATGCTCTCCAAGGCGAATGTGGGGGACGAGGCGCTCGCACAGTGGAAGGCCCTCGTGGACCTCGGGGACTTCGTGGCCG
TGACCGGGCGGGTCATCAGCTCCCGCCGGGGCGAGCTGTCCGTCATGGCGGACTCCTGGACCATGGCCTCCAAGGCCCTG
CGCCCCCTGCCCACCATGCACAAGGAGCTCAACGAGGAGACCAGGGTGCGCCAGCGCTACCTGGACCTGATCGTGCGCCA
GGAGGCGCGCGACGTCGTGCTCACCCGCTCCCTGATCACCCGCACCGTGCGCCGGGTCATGGAGCAGCAGGGGTACGTGG
AGATCGAGACGCCCATGCTGCAGCTCGTGCACGGCGGCGCCGCGGCGCGGCCGTTCGAGACCCACCTCAACGCCTTCGAC
CAGGACATGACCCTGCGCATCGCCACCGAGCTCTACCTCAAGCGCGCGGTGGTGGGCGGCATCGATAAGGTCTTCGAAAT
CGGGCGGGTATTCCGCAACGAGGGCGTGGATTCCTCCCACAGCCCGGAATTCACCACCCTGGAGGCCTACGAGGCCTACG
CGGACCAATTCGACATGGCGGACCGGATCCGGGAGATCATCCAGGAATGCGCGCGGCAGCTGGGCGTTGAGGGCATCGAC
ACCCCGCAGGGCCGCATCGAATTGTTCGGTGAATGGCAGTGGGTGTCCGTGTACCCGGGTCTGTCCGAGGCTGTGGGGCG
GGAGATCACCCCGGAAACCCCCGCGGAGCAGCTGCGCGCCGTGGCCGCCGAGCGGGACATTCCCGTGAATCCCGCGTGGG
ACGCCCAGAAGCTCGTCATGGAGCTCTTCGAGGAGATCGTGGAGCCCACGCTGCTCCAGCCCACCTTCGTGTACGACTAT
CCGCCCGCGGCCCAGCCCCTGGCGCGCCCGCACCGCGAGAAGCCCGGCGTGATCGAGGCGTGGGACCTCATCATCGGCGG
CATGGAGCGCGGCACCGCGTTCTCCGAGCTCGTGGACCCCGTGGTGCAGCGGGAACGGCTCACCGAGCAGTCGCTGCTGT
CCGCGGCGGGGGACCACGAGGCCATGCAGCTGGACGAGGACTTCCTGCGGGCGCTCGAGCACGGTGCCCCGCCCATGGGC
GGCATGGGGCTCGGCCTGGACCGGCTCATCATGCTCTTCACCAACCTCGGCATCAGGGAGACCATTCTCTTCCCGCTGAT
GAAGCCCGAGTGA

Protein sequence :
MTEQPETTVPAEPASTDPELSAHELNDQMAVRAAKRQAAADAGMHPYPVGVHRTATLASVRAEFGHLADGEETDHVVTVA
GRVVHVRNTGKLCFGTLQEGDGTRLQVMLSKANVGDEALAQWKALVDLGDFVAVTGRVISSRRGELSVMADSWTMASKAL
RPLPTMHKELNEETRVRQRYLDLIVRQEARDVVLTRSLITRTVRRVMEQQGYVEIETPMLQLVHGGAAARPFETHLNAFD
QDMTLRIATELYLKRAVVGGIDKVFEIGRVFRNEGVDSSHSPEFTTLEAYEAYADQFDMADRIREIIQECARQLGVEGID
TPQGRIELFGEWQWVSVYPGLSEAVGREITPETPAEQLRAVAAERDIPVNPAWDAQKLVMELFEEIVEPTLLQPTFVYDY
PPAAQPLARPHREKPGVIEAWDLIIGGMERGTAFSELVDPVVQRERLTEQSLLSAAGDHEAMQLDEDFLRALEHGAPPMG
GMGLGLDRLIMLFTNLGIRETILFPLMKPE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 3e-109 50
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 8e-67 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001855771.1 lysyl-tRNA synthetase VFG1668 Protein 4e-67 41