Gene Information

Name : thiC (MMAR_0735)
Accession : YP_001849050.1
Strain : Mycobacterium marinum M
Genome accession: NC_010612
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 882544 - 884184 bp
Length : 1641 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGACCGTTACTGTTGAGCCGTCCATCACGACTGGCCCCATCGCGGGCAGCAGCAAGGCCTATCGCGAGGTGGCCGGCCC
CGACGGGGTTACGCTGCGCGTCCCGTTGCGGCGGGTGCACCTGTCCACCGGCGCCGACTTCGACTTGTACGACACCTCCG
GGCCGTACACGGACCCAAATGCCGTGATCGACCTTGCCGTCGGCCTGCCGGCCCGGCCGGGGCTGGTCCGCGACCGTGGC
ACCCAGTTGCAGCGCGCCCGCGCCGGCGAAATCACCGCCGAGATGGCCTTCATCGCCGCCCGTGAGGGCATGTCCGCCGA
GCTGGTGCGCGACGAGGTGGCCCTCGGCCGTGCGGTGATCCCGGCCAACCACAACCACCCCGAGAGTGAGCCGATGGTGA
TCGGCAAGGCCTTCGCGGTGAAGGTCAACGCGAACATCGGCAACTCCGCGGTGACGTCCTCGATCGCCGAGGAGGTCGAC
AAGATGGTGTGGGCCACCCGCTGGGGGGCCGACACCATCATGGACCTGTCCACCGGCAAGAACATTCACGAGACGCGGGA
ATGGATTCTGCGCAACTCGCCGGTGCCGGTTGGCACGGTGCCCATCTATCAGGCGCTGGAGAAGGTCAAGGGCGACCCGA
CCGAGTTGACCTGGGAGCTCTACCGCGACACCGTGATCGAGCAGTGCGAGCAGGGTGTGGACTACATGACCGTGCACGCC
GGGGTGCTGCTGCGCTACGTGCCGCTGACCGCCAAGCGGGTCACCGGAATTGTTTCGCGCGGCGGGTCGATCATGGCGGC
GTGGTGCCTGGCGCACCACCGGGAATCGTTCCTGTACACCAACTTCGAGGAACTCTGCGACATTCTCGCGCGCTACGACG
TGACCTTCTCGCTTGGTGACGGGCTGCGGCCGGGCTCCATCGCCGACGCCAACGACGCCGCGCAGTTCGCCGAGTTGCGC
ACCCTGGGCGAGCTGACCAAGATCGCCAAAGCCCATGGGGTGCAGGTGATGATCGAGGGCCCCGGGCACGTTCCGATGCA
CAAGATCGTCGAGAACGTGCGGCTGGAAGAAGAGCTGTGCGAGGAGGCTCCCTTCTATACGCTGGGCCCGCTGGCCACCG
ATATCGCCCCGGCATACGACCACATCACGTCGGCGATCGGCGCAGCGATCATCGCGCAGGCCGGCACCGCGATGCTCTGC
TACGTCACTCCCAAGGAACACCTCGGACTGCCCGACCGCAAAGACGTCAAGGACGGGGTCATCGCCTACAAGATCGCCGC
GCACGCCGGCGACCTGGCCAAGGGCCACCCGCATGCGCAGGAGCGCGACAACGCCTTGTCACAGGCGCGTTTCGAGTTCC
GGTGGAACGATCAGTTCGCACTGTCGCTGGATCCCGACACGGCGCGCGAGTACCACGACGAGACACTGCCGGCCGAGCCC
GCTAAGACCGCCCACTTCTGCTCGATGTGCGGGCCGAAGTTCTGCTCCATGCGCATCACCCAGGATGTCCGCGACTACGC
GGCCAAGCACGGGCTGGACAGTGAGGAAGCCATTGAGGCGGCCCTGGAAGCGGGGATGGCGGAGAAGTCAGCCGAGTTCG
CCGACCACGGCAACCGGGTGTACCTGCCGATCACCCAGTGA

Protein sequence :
MTVTVEPSITTGPIAGSSKAYREVAGPDGVTLRVPLRRVHLSTGADFDLYDTSGPYTDPNAVIDLAVGLPARPGLVRDRG
TQLQRARAGEITAEMAFIAAREGMSAELVRDEVALGRAVIPANHNHPESEPMVIGKAFAVKVNANIGNSAVTSSIAEEVD
KMVWATRWGADTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWELYRDTVIEQCEQGVDYMTVHA
GVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDILARYDVTFSLGDGLRPGSIADANDAAQFAELR
TLGELTKIAKAHGVQVMIEGPGHVPMHKIVENVRLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLC
YVTPKEHLGLPDRKDVKDGVIAYKIAAHAGDLAKGHPHAQERDNALSQARFEFRWNDQFALSLDPDTAREYHDETLPAEP
AKTAHFCSMCGPKFCSMRITQDVRDYAAKHGLDSEEAIEAALEAGMAEKSAEFADHGNRVYLPITQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 4e-155 69
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 4e-155 69