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Name : leuS (MMAR_0057) Accession : YP_001848383.1 Strain : Mycobacterium marinum M Genome accession: NC_010612 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : - Position : 55690 - 58620 bp Length : 2931 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : GTGACCGAATCGCCGACCACGACACCTGGCAGCACGTCCGGTGCCCCCTCTGGTGTCCCCTCCGGTGTTAACGACGCGGA ATCCGACGCTCCGCGGCATCGTTACACCGCCGAGCTAGCGGCCGGAGTGGAGCGGACCTGGCAGCAGAACTGGGCCCGCC TGGGCACGTTCAACGTGCCCAACCCGGTTGGATCGCTCGCACCGTCGGACGGTTCCCCGGTGCCCGAGGACAAGCTGTTC GTCCAGGACATGTTTCCCTATCCATCCGGGGAGGGCCTGCACGTCGGGCACCCGTTGGGCTACATCGCCACCGACGTGTT CGCCCGCTATCACCGGATGAAGGGCCGCAACGTGCTGCATGCGTTGGGGTTCGACGCCTTCGGTCTGCCGGCCGAGCAGT ATGCCGTGCAAACCGGCACCCACCCACGGACCAGGACCGAGGCCAACGTCGTCAACTTCCGGCGCCAGCTGGGCCGGCTG GGGCTGGGCCACGACAGCCGGCGGAGCTTCTCTACCACCGACGTCGAGTTCTACAAGTGGACCCAGTGGATCTTCCTGCA GATCTACAACGCGTGGTTCGACGCGGCAGCCAACAAGGCTCGCCCGATTTCGGAGTTGGTCGCAGAGTTTGATTCCGGGG CCAGAAGTCTGGTCGACGGCCGGGACTGGTCCACGCTGTCGGCGGGGGAGCGGGCCGACGTGATCGATGACCACCGGTTG GTCTACCGGGCGGATTCGATGGTGAATTGGTGTCCTGGACTGGGCACGGTGCTGGCCAACGAGGAAGTGACATCCGATGG CCGCAGCGACCGCGGCAACTTCCCCGTATTTCGCAAGCGGCTTCGGCAATGGATGATGCGGATCACCGCATACTCCGATC GGCTGCTCGACGACCTCGATGTGCTGGACTGGCCGGACCAGGTCAAGACCATGCAGCGCAATTGGATCGGGCGCTCGACG GGTGCCTCCGCGCTCTTTACGGCAACCAGGTCCAACGGTGAGACGGTTGGCCTCGAAGTGTTCACCACTCGCCCCGACAC CCTGTTCGGTGCCACCTATCTGGTTCTGGCCCCCGAACACGACCTGGTCGACGATCTGGTTGGGGCCGGGTGGCCAGCCG GTGTGGACCCGCTGTGGACCGGTGGTGGTGCCACGCCGGCCGAGGCCGTGGCCGCCTACCGTCGCGCTATCGCGGCCAAG TCCGACCTCGAGCGTCAGGAAAGCAAAGAGAAGACCGGCGTCTTCCTGGGTAGCCACGCGATCAATCCCGCCACTGGCCA GCCGGTGCCGATATTCATCGCTGACTACGTGCTGGCCGGCTACGGCACCGGGGCCATCATGGCAGTTCCGGGCCATGATC AGCGGGACTGGGATTTCGCGAGAGCACTGGGACTTCCGGTCGTCGAAGTCATTGCCGGCGGCGACATTTCGCAGGCCGCC TACACCGGCGACGGCGTACTGGTGAACTCGGGGTTCCTCGACGGCATGAGCGTGGGGGAGGCAAAGCAGGCCATCACCGC TCGGCTGGAGTCCGACGGCCATGGCCAGGCCCGCATCGAATTCAAGCTGCGTGACTGGCTTTTCGCGCGTCAGCGGTATT GGGGTGAACCATTCCCGATCGTGTACGACGCGGATGGGCGCCCGCACGCACTTGATGAGTCGGCGCTTCCCGTCGAACTG CCCGATGTGCCGGACTATTCGCCGGTGCTTTTCGACCCCGACGATGCGAACAGCGAGCCGTCGCCGCCGCTGGGCAAGGC GACCGAGTGGGTGCACGTCGAGTTGGATCTCGGCGATGGGCTCAAGCCGTACAGCCGCGACACCAACGTGATGCCGCAGT GGGCGGGCAGCTCCTGGTACGAGCTGCGCTATACTGATCCGCACAACGCAGATCGGTTCTGCGCCAAGGAAAATGAGACG TACTGGATGGGGCCGAGGCCGGCCGAACACGGCCCGGACGACCCGGGTGGCGTCGACTTGTACGTCGGTGGCGCCGAGCA CGCGGTGCTGCATCTGCTCTATGCCAGGTTCTGGCACAAGGTGTTGTACGACTTGGGCCACGTCAGCTCTCGCGAGCCCT ACCGCAAGCTGATCAACCAGGGCTACATTCAGGCCTTCGCCTATACCGACGCGCGGGGATCCTACGTACCTGCCGAAGAG GTCATCGAACGTGACGGCGGGTTTGTGTATCCCGGTGCCGACGGCGAGATCGAGGTCTTTCAGGAATTCGGGAAAATCGG TAAGAGCCTGAAGAATTCGATATCGCCCGACGAGATCTGCGACGACTATGGCGCGGACACCCTGCGGGTGTACGAGATGT CGATGGGCCCTATCGAGGCTTCACGCCCGTGGGCGACCAAAGACGTTATCGGCGCGTATCGCTTCTTGCAGCGGGTGTGG CGGCTGGTGATCGACGAAAACACCGGCGAGATCCTGGTGGCCGATACGCCCGCTGAGTTGGACACCGACACGCTGCGGGC GCTGCACCGTGCTATCGCCGGGGTGGCTGAAGACTATGCGGCACTGAGAAATAACACCGCGGTCGCCAAGCTGATCGAGT ACACCAACTTCCTCACCAAGCGCCATCGCGATGCCGTGCCCCGAGCCGCCATCGAGCCGCTGGTGCTGATGGTGGCCCCG CTGGCCCCGCACCTGGCCGAAGAGTTGTGGCAGCGGCTGGGTCACACCACTTCGTTGGCGCACGGACCATTCCCGGCGGC CGATCCGGCCTATCTGATCGACGACACCGTCGAATATCCGGTTCAGGTCAACGGCAAGGTGCGGGGCCGGGTTGTGGTGG CCGCCGACGCGGATGACGATGCGGTCAAAGCCGCTGCCCTAGCCGATGAGAAGGTGCAGGCGTTCCTGGCGGGCGCAAGC CCGCGGAAGGTGATTGTGGTCGCCGGCCGTCTGGTGAATCTTGTTGTTTGA Protein sequence : MTESPTTTPGSTSGAPSGVPSGVNDAESDAPRHRYTAELAAGVERTWQQNWARLGTFNVPNPVGSLAPSDGSPVPEDKLF VQDMFPYPSGEGLHVGHPLGYIATDVFARYHRMKGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANVVNFRRQLGRL GLGHDSRRSFSTTDVEFYKWTQWIFLQIYNAWFDAAANKARPISELVAEFDSGARSLVDGRDWSTLSAGERADVIDDHRL VYRADSMVNWCPGLGTVLANEEVTSDGRSDRGNFPVFRKRLRQWMMRITAYSDRLLDDLDVLDWPDQVKTMQRNWIGRST GASALFTATRSNGETVGLEVFTTRPDTLFGATYLVLAPEHDLVDDLVGAGWPAGVDPLWTGGGATPAEAVAAYRRAIAAK SDLERQESKEKTGVFLGSHAINPATGQPVPIFIADYVLAGYGTGAIMAVPGHDQRDWDFARALGLPVVEVIAGGDISQAA YTGDGVLVNSGFLDGMSVGEAKQAITARLESDGHGQARIEFKLRDWLFARQRYWGEPFPIVYDADGRPHALDESALPVEL PDVPDYSPVLFDPDDANSEPSPPLGKATEWVHVELDLGDGLKPYSRDTNVMPQWAGSSWYELRYTDPHNADRFCAKENET YWMGPRPAEHGPDDPGGVDLYVGGAEHAVLHLLYARFWHKVLYDLGHVSSREPYRKLINQGYIQAFAYTDARGSYVPAEE VIERDGGFVYPGADGEIEVFQEFGKIGKSLKNSISPDEICDDYGADTLRVYEMSMGPIEASRPWATKDVIGAYRFLQRVW RLVIDENTGEILVADTPAELDTDTLRALHRAIAGVAEDYAALRNNTAVAKLIEYTNFLTKRHRDAVPRAAIEPLVLMVAP LAPHLAEELWQRLGHTTSLAHGPFPAADPAYLIDDTVEYPVQVNGKVRGRVVVAADADDDAVKAAALADEKVQAFLAGAS PRKVIVVAGRLVNLVV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 1e-136 | 46 |
