Gene Information

Name : trxB2 (MMAR_5477)
Accession : YP_001853738.1
Strain : Mycobacterium marinum M
Genome accession: NC_010612
Putative virulence/resistance : Unknown
Product : thioredoxin reductase TrxB2
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0492
EC number : -
Position : 6626782 - 6627780 bp
Length : 999 bp
Strand : +
Note : enzyme that catalyse the reduction of disulphides by pyridine nucleotides through an enzyme disulphide and a flavin. seems regulated by SigH. [catalytic activity: NADPH + oxidized thioredoxin = NADP(+) + reduced thioredoxin]

DNA sequence :
ATGACTACCGACTCTTCTGCTGACGCCACCATCCACGACGTGATCGTCATCGGCTCCGGTCCCGCCGGATACACCGCGGC
GCTCTACACCGCCCGTGCTCAGCTGGCTCCGCTGGTATTCGAGGGCACCTCGTTCGGTGGCGCGCTGATGACCACGACGG
AAGTGGAGAACTATCCCGGTTTTCGCGAAGGGATCACCGGCCCGGAGTTGATGGACGAGATGCGCGAGCAGGCGCTCCGT
TTCGGCGCCGACCTCCGCATGGAAGACGTCGAGTCGGTGTCGCTGGATGGGCCGATCAAATCGGTTGTCACCTCTGAGGG
AGAGACCCATCGGGCGCGCGCGGTGATCTTGGCGATGGGCGCGGCCGCGCGTTACCTGCACGTGCCCGGCGAACAGGAGC
TGCTGGGGCGCGGAGTGAGTTCCTGTGCCACCTGTGACGGATTTTTCTTCCGCGACCAGGACATCGCGGTGATCGGCGGC
GGCGACTCCGCGATGGAAGAGGCAACCTTCCTCACTCGGTTCGCCCGCAGCGTGACCCTGGTGCACCGTCGCGACGAGTT
CCGGGCCTCCAAGATCATGATCAATCGGGCCCAGGCCAACGACAAGATCCGCATCCTGACCAACAAGATCGTCCTCGCGG
TGGACGGGGAGACGACCGTCACCGGACTGCAGTTGCGCGACACCGTCACCGGGGAAGAAACCACCCTGCCGGTAACCGGC
GTGTTCGTCGCGATCGGGCACGAACCGCGATCGAGCCTGGTGCGCGACGCCGTCGACGTCGACCCCGATGGCTACGTGCT
GGTGAACGGGCGCACCACCGGCACCTCGCTGGAAGGTGTTTTCGCCGCCGGCGACCTGGTGGACCGCACCTACCGGCAGG
CGGTCACCGCCGCCGGCAGCGGGTGCGCCGCGGCCATAGACGCCGAGCGTTGGCTGGCCGAACATGAAGCAACTGGAGAC
GCCGACAGTACCGACACGCTGATTGGAGCACAGCAATGA

Protein sequence :
MTTDSSADATIHDVIVIGSGPAGYTAALYTARAQLAPLVFEGTSFGGALMTTTEVENYPGFREGITGPELMDEMREQALR
FGADLRMEDVESVSLDGPIKSVVTSEGETHRARAVILAMGAAARYLHVPGEQELLGRGVSSCATCDGFFFRDQDIAVIGG
GDSAMEEATFLTRFARSVTLVHRRDEFRASKIMINRAQANDKIRILTNKIVLAVDGETTVTGLQLRDTVTGEETTLPVTG
VFVAIGHEPRSSLVRDAVDVDPDGYVLVNGRTTGTSLEGVFAAGDLVDRTYRQAVTAAGSGCAAAIDAERWLAEHEATGD
ADSTDTLIGAQQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
trxB AFC76431.1 TrxB Not tested AbaR5 Protein 5e-54 44
trxB CAJ77014.1 thioredoxin reductase Not tested AbaR1 Protein 4e-54 44