Gene Information

Name : ureA (MMAR_2722)
Accession : YP_001851019.1
Strain : Mycobacterium marinum M
Genome accession: NC_010612
Putative virulence/resistance : Virulence
Product : urease subunit gamma
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0831
EC number : -
Position : 3323725 - 3324090 bp
Length : 366 bp
Strand : +
Note : UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter

DNA sequence :
GTGACCTCAGTCACTCTCGCCTCGAAAGGCCAGAACCGTCACGGCGTGGCAGGATCCCAAAGCATGCGCTTGACGCCGCA
CGAACAGGAGCGATTGCTGCTGTCTTACGCCGCCGAGGTGGCCCGCCGCCGACAGGCTCGCGGCTTGCGTCTCAATCACC
CCGAGGCCGTAGCGCTCATCACCGACCACGTCCTTGAAGGTGCACGCGACGGCCGCACGGTGGCCGAGCTGATGGCCAGC
GGTTGTGAGGTCCTGGGTCGAGACGATGTGATGGAAGGAGTGCCCGAGATGATCGCGGACGTGCAGGTTGAGGCGACCTT
CCCGGACGGCACCAAATTGGTCACCGTCCATCATCCGATCCGATGA

Protein sequence :
MTSVTLASKGQNRHGVAGSQSMRLTPHEQERLLLSYAAEVARRRQARGLRLNHPEAVALITDHVLEGARDGRTVAELMAS
GCEVLGRDDVMEGVPEMIADVQVEATFPDGTKLVTVHHPIR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureA YP_005682176.1 urease subunit gamma Not tested PiCp 7 Protein 4e-33 73
ureA YP_005684268.1 urease subunit gamma Not tested PiCp 7 Protein 4e-33 73
ureA YP_003784327.1 urease subunit gamma Not tested PiCp 7 Protein 4e-33 73
ureA YP_005686360.1 urease subunit gamma Not tested PiCp 7 Protein 4e-33 73
ureA NP_286678.1 urease subunit gamma Virulence TAI Protein 1e-25 66
ureA NP_287086.1 urease subunit gamma Not tested TAI Protein 1e-25 66