Gene Information

Name : guaB1 (MMAR_2717)
Accession : YP_001851014.1
Strain : Mycobacterium marinum M
Genome accession: NC_010612
Putative virulence/resistance : Unknown
Product : inosine 5-monophosphate dehydrogenase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0516
EC number : -
Position : 3318451 - 3319887 bp
Length : 1437 bp
Strand : -
Note : catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate

DNA sequence :
ATGAGGTTCTTGGACGGGCATCGGCCCGGGTACGACCTGACGTACAACGACGTATTCATCATGCCGAATCGCTCCCTGGT
GGCGTCCCGGTTCGACGTGGATCTGTCGACCGCCGACGGTTCGGGTACCACCATTCCCGTGGTGGTGGCCAACATGACCG
CGGTGGCCGGGCGGCGGATGGCCGAGACCGTGGCCCGCCGCGGTGGCATCGTGGTTCTGCCGCAGGATCTGCCCATCCCG
GCGGTGCACCAAACCGTGGAGTTCATCAAGAGCCGCGACCTGGTGCTAGACACGCCGGTGACGCTGGCCCCCGAGGATTC
GGTATCCGATGCGATCGCGTTGATCCACAAACGTGCCCATGGGGTCGCCGTTGTGGTCTCCGAGGGCCGCCCAATCGGCT
TGGTGACCGAAGCGTCCTGCGTGGGCGTGGACCGCTTCGCCCGGGTGCGCGATATCGCCGCCCTGGACTTTGTCAGCGCT
CCGGTGGGCACCGAGCCGCGAAAGGTCTTCGATCTGCTCGAGCACTCGCCCATCGAGGTTGCGGTGCTGACCCGGCCCGA
TGGCACGCTCGCCGGCGTGCTGAGCCGGACCGGGGCGATCCGCGCCGGGATCTACACGCCGGCCACCGACGCGGCCGGCC
GGCTGCGCATCGCGGCGGCCGTCGGTATCAATGGCGACGTGGCCGCCAAAGCGGGCGCCCTGGCCGAGTCAGGGGTGGAC
CTGCTGGTCATCGACACCGCCCACGGGCACCAGGTCAAGACACTGGATGCGATCAGTGCGGTCGCATCGCTGGATCTGGG
CCTTCCGTTGGCGGCGGGCAACGTGGTGTCTGCCGAGGGCACGCGGGACCTTCTGGGCGCCGGTGCCGACATCGTCAAGG
TGGGCGTTGGTCCCGGCGCCATGTGCACGACCCGGATGATGACCGGTGTCGGGCGGCCGCAGTTTTCCGCCGTGCTCGAA
TGCTCCGCTGCGGCAAGGGAGCTTGGCGGGCACGTATGGGCCGACGGCGGGATCCGTCATCCTCGCGATGTCGCACTGGC
GCTGGCAGCAGGCGCGTCCAACGTGATGATCGGATCCTGGTTCGCGGGCACCTATGAGTCCCCCGGCGACCTGATGCGCG
ACCGCGAAGACCAGCCCTACAAGGAGAGCTACGGCATGGCTTCCAAGCGTGCGGTAGTCGCTCGGACCACCACCGACAGC
GCGTTCGATCGGGCCCGAAAGTCGCTGTTCGAGGAAGGCATTTCGACGTCGCGGATGGGGCTCGACCCCGATCGCGGCGG
AGTGGAGGACTTGATCGACCACATCACATCCGGCGTGCGCAGCACTTGCACCTACGTCGGCGCGTCGAATCTGGCCGAAC
TTCATGAACAGGTGGTCATCGGCGTGCAGTCAGCGGCCGGCTTTGCCGAGGGGCATCCCCTACCCGCCGGCTGGTGA

Protein sequence :
MRFLDGHRPGYDLTYNDVFIMPNRSLVASRFDVDLSTADGSGTTIPVVVANMTAVAGRRMAETVARRGGIVVLPQDLPIP
AVHQTVEFIKSRDLVLDTPVTLAPEDSVSDAIALIHKRAHGVAVVVSEGRPIGLVTEASCVGVDRFARVRDIAALDFVSA
PVGTEPRKVFDLLEHSPIEVAVLTRPDGTLAGVLSRTGAIRAGIYTPATDAAGRLRIAAAVGINGDVAAKAGALAESGVD
LLVIDTAHGHQVKTLDAISAVASLDLGLPLAAGNVVSAEGTRDLLGAGADIVKVGVGPGAMCTTRMMTGVGRPQFSAVLE
CSAAARELGGHVWADGGIRHPRDVALALAAGASNVMIGSWFAGTYESPGDLMRDREDQPYKESYGMASKRAVVARTTTDS
AFDRARKSLFEEGISTSRMGLDPDRGGVEDLIDHITSGVRSTCTYVGASNLAELHEQVVIGVQSAAGFAEGHPLPAGW

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Cp1002_1469 YP_005681736.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 2e-137 58
cpfrc_01479 YP_003783879.1 hypothetical protein Not tested PiCp 5 Protein 6e-137 58
CpC231_1472 YP_005683835.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 8e-137 57
CpI19_1479 YP_005685921.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 8e-137 57