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Name : lysS (MMAR_2447) Accession : YP_001850752.1 Strain : Mycobacterium marinum M Genome accession: NC_010612 Putative virulence/resistance : Unknown Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : - Position : 2955106 - 2958399 bp Length : 3294 bp Strand : - Note : catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA DNA sequence : GTGCAGGGTAGGCACATCTCTCGGTATGACTGGGTTCCGGCCGCCGCTGGCTGGGCCGTCGGGGTCATCGCGACCCTGTC ACTGCTGGCCAGCATTTCGCCGCTGGTTCGGTGGATCATCAAGGTTCCCCGAGAATTCATCAACAGTTATCTGTTCAATT TTCCCGACACCAGCTTCGCCTGGTCTTTTGTGCTGGCACTGCTGGCGGCGGCCCTGGCCGCGCGTAAACGGATCGCCTGG CTACTGCTGCTGACCAACGTCGTCTTGGCGGCTTTCCTCAACGCCGCCGACATCGCCGCGGGCGGCAACACCGCGGCCCA GAACTTCGGCGAAAACCTCGGGTTCGCAGTACACGTGGTGGCGATCGTCGTGCTGGTGCTGGGATATCGGCAGTTCTGGG CCAAGGTCCGCAGGGGTGCACTGTTCAAGGCGGCCGCGGTGCTGGTGGCCGGTGGTGCGATCGGAATCCTGGTGTCCTGG GGCCTGGTCGAGCTGTTTCCGGGATCCCTCGCGCCGCACGACCGTTTGCCCTACGTGGCCAACCGGGTGATCGGCTTCGC CCTGGCCGATCCCGACCTGTTCACCGGCCGGCCGCACGTCTTCCTCAACGCCATGTTCGGCTTGTTCGGCGCTCTCGCCC TAATTGCGGCCACCATCGTGCTGTTTCAGTCCCAGCGTGCCGATAACGCGTTGACCGGCGAGGACGAGTCGGCCATCCGG GGGTTGCTCGAGCTGTACGGCAACAGCGACTCGCTGGGCTACTTCGCGACCCGTCGCGACAAGTCGGTGATATTCGCCTC CAGCGGCCGTGCCGCCATCACCTATCGGGTCGAAATCGGTGTCTGCCTGGCCAGTGGCGATCCGGTAGGCGACCCGCGGT CGTGGCCGCAAGCGATCGACGCATGGCTACGGCTGTGCCAGACCTATGGTTGGTCGCCCGGTGTGATGGGGGCCAGTTCA CAAGGGGCCAAGGCATATCGCGAGGCGGGTCTGAACGCGCTTGAACTCGGCGACGAGGCGATCTTGGTGCCCGCCGATTT CACGCTGTCCGGCCCCGACATGCGCGGCGTGCGCCAAGCCGTGACCAGGGCACGTCGCGCCGGTCTGACGGTGCGCATCC GGCGTCACCGGGATATCTCCGACGCCGAAATGGAACAGACGATCGATCGCGCCGACGGCTGGCGCGACACCGAATCCGAG CGCGGCTTCTCGATGGCGCTGGGCCGCCTCGGCGACCCGGCCGACACCGACTGCTTGTTGGTCGAGGCGCTTGACCCCGA CGACCTGGTAGTGGCGATGTTGTCGCTGGTGCCTTGGGGTACCAGCGGGGTCTCCCTGGACCTGATGAGACGTTCTCCGC AATCGCCCAACGGCACCATCGAGCTGATGGTCAGCGAACTGGCGCTGCGCGCCGAAGGCCTCGGCATCAGCCGCATCTCG CTGAACTTCGCGATGTTCCGGTCGGCTTTCGAGCAAGGCGCCCAATTGGGCGCCGGGCCGGTGGCCCGCTTGTGGCGTTG GCTGCTGGTGTTCTTTTCCCGGTGGTGGCAGATCGAGACGCTGTACCGATCCAACCAGAAGTATCAGCCGCAATGGGTGC CCCGCTACGCCTGCTATGAGGACGCGCGGGTGATCCCCAAGGTGGGTGTCGCCTCCGTGATCGCCGAGGGGTTCCTGGTA TTGCCATTCAGCCGGCGCAACAAGGTGCACACCGGTCACCATCCCGCGGTCCCCGAACGGCTGGCGGCCACCGGTTTGTT GCACCATGACGGATCGGCGCCCGACGTCAGCGGGCTGCGGCAATCGGCAATTGCCGACGGCGACGACCCCCAACGTCGGC TGCCCGAGCAAGTCCGGGTGCGGCTGAACAAGTTGAAGAAATTGCGCAGCAGCGGCATTGACGCCTATCCGGTGGGCGAA CCGCCCACTCATACAGTCGCGCAAGCGATGGATGCCGACGACCAGGCGAGCGTGTCGGTATCCGGGCGGATCTTGCGGGT ACGCAACTACGGTGGAGTGCTGTTCGCGCACTTGCGCGACTGGAGCGGCGAGATTCAGGTGCTGCTGGACAACTCGCGAC TCGAGCAGGGCCGCGCCGCGGATTTCAACGCGGCCATAGACCTTGGTGACCTGGTCGAGATGACCGGGCAGATGGGTTCG AGCAAGACCGGAACGCGATCACTGATCGTGCGCCGCTGGCGTCTGATCGGTAAGTGCCTGCGCCCCTTGCCCAACAAGTG GAAGGGGTTGACCGATCCCGAAGCCCGAGTGCGGACCCGCTACGTAGACCTCGCTGTCAACGCCGAGTCGCGCGCCCTCA TCACGGCCCGCAGCGCGGTGCTGCGCTCCGTCCGAGAAACCCTGTCCGCCAAGGGGTTCATCGAGGTCGAGACACCCATC CTGCAACAGGTACACGGCGGCGCAACGGCCCGCCCGTTCATCACCCACATCAACACCTACTCCATGGACCTGTTCTTGCG CATCGCGCCGGAGCTGTATCTCAAGCGGCTGTGCGTCGGCGGGGTGGAACGGGTCTTCGAACTCGGCCGGGCCTTTCGGA ATGAGGGCGTCGACTTCAGCCACAACCCGGAGTTCACCCTGTTGGAGGCCTATCAAGCGCACGCCGACTACCGGGTATGG ATCGACAGCTGCCGCGAGCTGATCCAAAACGCCGCCCAGGCCGCCAACGGTGCACCCGTCGCGATGCGCCCGGCCGGCGG CGGCCGCCTCGAACCGGTGGACATCTCGGGGGTCTGGGCGGTCAAGACCGTGCACGACGCGGTGTCAGAGGCCCTCGGTG AGCAGATCGACGCCGATACCGACTTGGCCACCCTGCGCAGGCTGGCCGACGCCGCACGCATCCCCTATCGGGCGCAGTGG GATGCCGGCGCGGTGGTGCTGGAGCTCTACGAACACCTGGTGGAGAGCCGCACCGAGCAGCCGACGTTCTACCTCGACTT CCCGACCTCGGTGTCCCCGCTGACCCGGCCGCATCGCAGCAAGCCCGGAATCGCCGAACGTTGGGACCTGGTGGCCTGGG GCGTCGAGCTTGGTACCGCCTACAGCGAGCTCACCGACCCCGTCGAACAGCGGCTCCGCTTGGAGGAGCAGTCTTTGCTC GCCGCCGGCGGGGATCCCGAAGCGATGCAGCTCGACGAAGACTTCCTGCAGGCCATGGAATACGCGATGCCGCCCACCGG GGGCCTCGGCATGGGCGTCGACCGGGTCGTCATGCTGATCACCGGGCGCAGCATCCGTGAAACGCTCCCGTTCCCGCTGG CCAAGCCGCACTAA Protein sequence : MQGRHISRYDWVPAAAGWAVGVIATLSLLASISPLVRWIIKVPREFINSYLFNFPDTSFAWSFVLALLAAALAARKRIAW LLLLTNVVLAAFLNAADIAAGGNTAAQNFGENLGFAVHVVAIVVLVLGYRQFWAKVRRGALFKAAAVLVAGGAIGILVSW GLVELFPGSLAPHDRLPYVANRVIGFALADPDLFTGRPHVFLNAMFGLFGALALIAATIVLFQSQRADNALTGEDESAIR GLLELYGNSDSLGYFATRRDKSVIFASSGRAAITYRVEIGVCLASGDPVGDPRSWPQAIDAWLRLCQTYGWSPGVMGASS QGAKAYREAGLNALELGDEAILVPADFTLSGPDMRGVRQAVTRARRAGLTVRIRRHRDISDAEMEQTIDRADGWRDTESE RGFSMALGRLGDPADTDCLLVEALDPDDLVVAMLSLVPWGTSGVSLDLMRRSPQSPNGTIELMVSELALRAEGLGISRIS LNFAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQIETLYRSNQKYQPQWVPRYACYEDARVIPKVGVASVIAEGFLV LPFSRRNKVHTGHHPAVPERLAATGLLHHDGSAPDVSGLRQSAIADGDDPQRRLPEQVRVRLNKLKKLRSSGIDAYPVGE PPTHTVAQAMDADDQASVSVSGRILRVRNYGGVLFAHLRDWSGEIQVLLDNSRLEQGRAADFNAAIDLGDLVEMTGQMGS SKTGTRSLIVRRWRLIGKCLRPLPNKWKGLTDPEARVRTRYVDLAVNAESRALITARSAVLRSVRETLSAKGFIEVETPI LQQVHGGATARPFITHINTYSMDLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYRVW IDSCRELIQNAAQAANGAPVAMRPAGGGRLEPVDISGVWAVKTVHDAVSEALGEQIDADTDLATLRRLADAARIPYRAQW DAGAVVLELYEHLVESRTEQPTFYLDFPTSVSPLTRPHRSKPGIAERWDLVAWGVELGTAYSELTDPVEQRLRLEEQSLL AAGGDPEAMQLDEDFLQAMEYAMPPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPH |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| lysS1 | YP_005682181.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 2e-153 | 44 |
| lysS1 | YP_005684273.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 8e-154 | 44 |
| lysX | YP_003784331.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 8e-154 | 44 |
| lysS1 | YP_005686365.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 8e-154 | 44 |
