Gene Information

Name : tkt (MMAR_2254)
Accession : YP_001850558.1
Strain : Mycobacterium marinum M
Genome accession: NC_010612
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : -
Position : 2710962 - 2713064 bp
Length : 2103 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
GTGACCACTCTCGAAGAGATCTCTGCGCTCACCCAACCGCGCCATCCCGACGACTGGACCGAGATCGATTCGGCTGCGGT
TGACACGGCCCGAGTGCTGGCAGCCGACGCCGTGCAAAAGGTCGGCAATGGACACCCGGGAACTGCGATGAGCCTGGCCC
CGCTGGCCTACACGTTGTTTCAGCGCGCGATGCGCCATGACCCCAGCGACACCACTTGGTTGGGCCGGGACCGGTTCGTC
CTGTCCTGCGGACACAGCAGCCTGACCCTCTACATACAGCTCTACCTGGGCGGCTTCGGGCTTGAATTGTCCGACATCGA
GTCGCTGCGCACCTGGGGGTCCAAGACTCCCGGGCATCCCGAGTTCCGCCACACCGCCGGGGTGGAGATCACCACGGGTC
CGCTGGGCCAGGGCCTGGCTTCAGCGGTGGGCATGGCGATGGCGGCGCGCTATGAGCGTGGCCTGTTCGACCCCGACGCC
GAACCCGGAACCAGCCCCTTCGACCATCACATTTACGTGATCGCCTCCGACGGTGACATCGAAGAGGGAGTCACCTCCGA
GGCGTCGTCTCTTGCGGCCGTTCAACAGCTGGGCAACCTCATCGTCTTCTACGACCACAACAAGATCTCGATCGAGGACG
ACACCAACATCGCGCTGTGCGAAGACACCGCTGCTCGCTACCGCGCCTACGGCTGGCACGTGCAAGAGGTGGAGGGCGGC
GAGAACGTCACCGGCATCGAGGAGGCGATCGCCAACGCGAAGGCGGTCACCGATCGGCCCTCGTTCATCTCGCTGCGCAC
CATCATCGGCTACCCGGCGCCGAACATGATGAACACGGGCAAGGTGCATGGTGCGGCGCTTGGTGACGAGGAAGTGGCGG
CCGTCAAGACAGTCCTCGGATTCGATCCCAACAATGCGTTCGAAGTGCGCGAAGACGTCATCACGCACACCCGCGGGTTG
GTGGCGCGCGGCAAGGAGGCGCACGAAAGCTGGCAGGCCGACTTTGAGGCCTGGGCGCAGCGGGAACCGCAGCGCAAGGC
CTTGCTGGACCGTCTGACGGCCCAGCAGCTGCCCGACGGCTGGGATGCCGACATGCCGCGCTGGGAGCCCGGTTCCAAAG
CACTGGCCACGCGGGCAGCGTCCGGACAGGTGCTGGCCGCGATCGGCCCCAAACTCCCCGAGTTGTGGGGCGGTTCGGCT
GACCTTGCCGGCAGCAACAACACCACCATCAAGGGCGCGGACTCATTCGGCCCGCCAGCGATCTCTACCGATGACTACAC
CGCGCACTGGTACGGCCGCACGCTGCACTTCGGTGTTCGCGAGCACGCGATGGGCGCCATCCTCTCCGGGATCGCGCTGC
ACGGACCCACCCGCGCCTACGGTGGCACGTTCCTGCAGTTCTCCGATTACATGCGCCCGGCAGTGCGGCTGGCGGCACTG
ATGGACATCGACCCCATTTACGTCTGGACCCACGATTCGATCGGACTGGGTGAAGACGGCCCGACCCACCAGCCGATCGA
GCACCTTTCGGCGTTGCGCGCGATCCCCCGGCTCGCGGTGGTGCGCCCGGCCGACGCCAATGAGACGGCGTACGCCTGGA
GCACGATCCTGGCCCGGGGCGCCACCAGCGGTCCGGTCGGGCTGATCCTGACCCGGCAGGGAGTGCCGGTGCTAGCGGGC
ACCAACGCCGAGGGCGTTGCCCGCGGTGGCTACGTGCTCAGCGATGGCGCCGACGGTGACTCGTCCGAAGACCCCGACGT
CGTTTTGATCGCCACCGGTTCCGAGGTGCAGCTTGCGGTCGAAGCACGGAAGTTGTTGGCGGATAACGACATCATCGCGC
GAGTGGTATCGATGCCGTGCGTGGAGTGGTTTGAGTCCCAGCCTGAGGAATACCGCGACAGTGTGTTGCCGCCGTCGGTT
TCGGCCCGGGTGGCCGTCGAGGCCGGCATCGCACAGTGCTGGCACAAGCTGGTCGGTGACACCGGCAAGATCGTTTCGAT
CGAGCACTACGGAGAGTCCGCCGACTACAAGACATTGTTCCGCGAGTACGGCTTTACCGCCGAAGCTGTTGCCGCTGCCG
CGGAACGAGCATTGGAAAATTGA

Protein sequence :
MTTLEEISALTQPRHPDDWTEIDSAAVDTARVLAADAVQKVGNGHPGTAMSLAPLAYTLFQRAMRHDPSDTTWLGRDRFV
LSCGHSSLTLYIQLYLGGFGLELSDIESLRTWGSKTPGHPEFRHTAGVEITTGPLGQGLASAVGMAMAARYERGLFDPDA
EPGTSPFDHHIYVIASDGDIEEGVTSEASSLAAVQQLGNLIVFYDHNKISIEDDTNIALCEDTAARYRAYGWHVQEVEGG
ENVTGIEEAIANAKAVTDRPSFISLRTIIGYPAPNMMNTGKVHGAALGDEEVAAVKTVLGFDPNNAFEVREDVITHTRGL
VARGKEAHESWQADFEAWAQREPQRKALLDRLTAQQLPDGWDADMPRWEPGSKALATRAASGQVLAAIGPKLPELWGGSA
DLAGSNNTTIKGADSFGPPAISTDDYTAHWYGRTLHFGVREHAMGAILSGIALHGPTRAYGGTFLQFSDYMRPAVRLAAL
MDIDPIYVWTHDSIGLGEDGPTHQPIEHLSALRAIPRLAVVRPADANETAYAWSTILARGATSGPVGLILTRQGVPVLAG
TNAEGVARGGYVLSDGADGDSSEDPDVVLIATGSEVQLAVEARKLLADNDIIARVVSMPCVEWFESQPEEYRDSVLPPSV
SARVAVEAGIAQCWHKLVGDTGKIVSIEHYGESADYKTLFREYGFTAEAVAAAAERALEN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 1e-119 43
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 3e-122 43