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Name : hsdM (MMAR_1959) Accession : YP_001850264.1 Strain : Mycobacterium marinum M Genome accession: NC_010612 Putative virulence/resistance : Unknown Product : type I restriction/modification system DNA methylase HsdM Function : - COG functional category : V : Defense mechanisms COG ID : COG0286 EC number : - Position : 2377730 - 2379184 bp Length : 1455 bp Strand : + Note : implicated in methylation of DNA. component of type I restriction/modification system. it is possible that the M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of bipartite DNA recogn DNA sequence : ATGGCACCGTCGACGATGAAAGAGCTCAAAGACACGCTCTGGAAAGGCGCCGAGAAGCTGCGCGGGTCCATTCCGGCCAG CCAGTACAAAGACGTCATTCTCGGCCTGGTCTTTCTCAAGTTCGTTTCCGATGCCCGAGACGGGCGCAAGCCATTCGTGG TGCCCCCCGAAGCGCGCTGGGAAGCGTTGGCCGGCAATGCGAAATCACCGGACATCGGCCAGCTCATCGACACGGCGATG CTGTCGGTAATGACGGCCAATCCGTCGCTGGCCGCGACCCTGCCGCAGCTGTATCACAAGGTCGATCAGCGGCGGCTCGG CGAACTGGTCGAGGTGCTCGGCGCGGCGCGATTCAGTGGCCGGCCAAGCCATCGCGCGCGTGACCTGATGGGTGAGGTGT ACGAATACTTCCTCGGCAACTTCGCGCGCGCGGAGGGACGACGCGGCGGCGAATTCTTCACCCCACCCAGCGTCGTTCGA GTGATCGTGGAGATTCTCGAACCCTCGAGCGGTCGGATCTATGACCCGTGCTGCGGATCGGGCGGGATGTTCGTGCAAAC CGAGCGCTTCATCTGCGCCCACGACGGGGACCCCGCGCAGATATCGATCTACGGTCAGGAGAGCGTCGAGCAGACCTGGC GGATGGCAAAGATGAACCTGGCCGTCCATGGGATCGATGATGCGGGCCTGGGCGCGCGTTGGGGCGACACCTTCGCCACC GACCAACACGACGGCGTGCCGATGGACTACGTGATGGCCAATCCGCCCTTCAACATCAAGGATTGGGCCCGCGACGAACA GGACCCGCGTTGGCGGTTCGGCACTCCGCCCGCCGCAAATGCGAACTTCGCCTGGATTCAGCACATCCTGTCCAAGCTCG CGCCGACAGGTCAGGCCGGGGTGGTGATGGCCAATGGCTCGATGTCATCGAAAACCAATGGAGAGGACAGGATTCGCGCT GGAATCATTGATGCAGACCTGGTCTCATGCATGGTCGCCCTGCCGACGCAGCTGTTTCGCAGTACCGGAATTCCGGTGTG TCTGTGGTTCTTCGCCAAGGACAAGAAAGCTCGTTCGGGCCAGGTGCTGTTCATCGACGCGCGCGGGCTCGGGAGCATGG TGGACCGCTGCGAGCGAACCCTGACCGATGACGACGTAGCCCGCATCGGCGATACCTATCACGGCTGGTTCGGATCCGCA TCATCCGTCGCGAAAGGTACTGTTTACCAGGATATTCCGGGATTTTGCAGGTCAGCATCGTTGGATGAGATCCGCGCCGA GGGGTACGTGCTCACGCCGGGGCGCTATGTGGGGACTGGAGCGTCCTGTGCTGACGGCGAACCGATCGGCGACAAACTCG CAAGGTTGACCACCCAGTTGCTGGCCGCGCTGGATGAATCGACAAAACTGGACGAGGCGGTGCGTGCGCAGTTGGGGCGG GTGCGGTGGAGGTGA Protein sequence : MAPSTMKELKDTLWKGAEKLRGSIPASQYKDVILGLVFLKFVSDARDGRKPFVVPPEARWEALAGNAKSPDIGQLIDTAM LSVMTANPSLAATLPQLYHKVDQRRLGELVEVLGAARFSGRPSHRARDLMGEVYEYFLGNFARAEGRRGGEFFTPPSVVR VIVEILEPSSGRIYDPCCGSGGMFVQTERFICAHDGDPAQISIYGQESVEQTWRMAKMNLAVHGIDDAGLGARWGDTFAT DQHDGVPMDYVMANPPFNIKDWARDEQDPRWRFGTPPAANANFAWIQHILSKLAPTGQAGVVMANGSMSSKTNGEDRIRA GIIDADLVSCMVALPTQLFRSTGIPVCLWFFAKDKKARSGQVLFIDARGLGSMVDRCERTLTDDDVARIGDTYHGWFGSA SSVAKGTVYQDIPGFCRSASLDEIRAEGYVLTPGRYVGTGASCADGEPIGDKLARLTTQLLAALDESTKLDEAVRAQLGR VRWR |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hsdM | YP_251979.1 | type I restriction-modification system DNA methylase | Not tested | SCCmec | Protein | 9e-117 | 47 |
| hsdM | BAH57701.1 | type I restriction-modification system DNA methylase | Not tested | Type-VII SCCmec | Protein | 6e-117 | 47 |
| hsdM | BAD24842.1 | HsdM protein | Not tested | Type-V SCCmec | Protein | 1e-116 | 46 |
| api49 | CAF28523.1 | putative HsdM-like N-methyl transferase | Not tested | YAPI | Protein | 2e-91 | 45 |
