Gene Information

Name : drrA (MMAR_1771)
Accession : YP_001850075.1
Strain : Mycobacterium marinum M
Genome accession: NC_010612
Putative virulence/resistance : Unknown
Product : daunorubicin-DIM-transport ATP-binding protein ABC transporter DrrA
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1131
EC number : -
Position : 2143027 - 2144022 bp
Length : 996 bp
Strand : -
Note : probably involved in active transport of antibiotic and phthiocerol dimycocerosate (dim) across the membrane (export). DrrA, DrrB and DrrC may act jointly to confer daunorubicin and doxorubicin resistance by an export mechanism. responsible for energy cou

DNA sequence :
ATGCGTAACAACGACTTGGCGGTAGAGGTTCGCGGGGTTCGCAAGGCCTTTGGCGACGTCGTGGCTCTCAACGACATCAG
TTTCGAGGTTGGCCGCGGCGAGGTCATCGGTCTACTCGGCCCGAACGGGGCGGGCAAGACGACCATGGTGGACATCTTGT
CCACCTTGACCCGCCCGGATGCCGGCTCGGCCCACGTCGCCGGCTCCGACGTCGTCGCCCAGCCGGCCGGAGTGCGGCGC
TCGATCATGGTCACCGGGCAACAAGTGGCCGTCGACGACGGGCTGACCGGGGAGCAGAACCTGGTGTTGTTCGGCCGCCT
CTACGGGCTGCGCAAGTCCCGTGCTCGCCAGCGGGCGCAGGAACTCCTCGATCAATTTGGCCTCACCTATGCCGGCAAGC
GGCTGGTGCGCACCTACTCAGGCGGGATGCGTCGACGCATCGACATCGCGTGCGGACTGGTGGTCGAGCCGCAAGTGGCG
TTCTTGGACGAGCCGACCACGGGGCTGGATCCCAGAAGCCGACAAGCCATTTGGGACCTGGTCACCAGTTTCAAGAAGCT
TGGCATCGCCACCCTGCTGACCACGCAGTATCTCGAGGAGGCGGACGCGCTCAGCGACCGGATCATCCTGATCGATCACG
GCAAGATCATTGCCGACGGTACTGCCAATGAGCTCAAGCACCGCGCCGGCGACACCTTCTGCGAGATTGTGCCGCGGCAT
CTGAAGGATCTGGACGCTACCGTCGCCGCCCTCGGCTCGCTGTTGCCCGAGCACAACAGGGCCATGGTGACCTCGGAATC
GGACCGCATCACGATGCCGGCTCCCGATGGCACCCGCACCCTCATCGAAGCGGCCCGAAGGATCGATGAGGCCAATATCG
AGCTGGCCGACATCGCGCTGCGCCGGCCGTCTCTTGATGACGTATTCCTTTCCATGACAACCGATCCCAGCGAGGCCCAC
GCGCTGAGTCACGTGGCGTCGGGGGCCATGCTGTGA

Protein sequence :
MRNNDLAVEVRGVRKAFGDVVALNDISFEVGRGEVIGLLGPNGAGKTTMVDILSTLTRPDAGSAHVAGSDVVAQPAGVRR
SIMVTGQQVAVDDGLTGEQNLVLFGRLYGLRKSRARQRAQELLDQFGLTYAGKRLVRTYSGGMRRRIDIACGLVVEPQVA
FLDEPTTGLDPRSRQAIWDLVTSFKKLGIATLLTTQYLEEADALSDRIILIDHGKIIADGTANELKHRAGDTFCEIVPRH
LKDLDATVAALGSLLPEHNRAMVTSESDRITMPAPDGTRTLIEAARRIDEANIELADIALRRPSLDDVFLSMTTDPSEAH
ALSHVASGAML

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
CDC7B_2054 YP_005163495.1 methionine import ATP-binding protein Not tested Not named Protein 1e-60 44
CDCE8392_1976 YP_005134507.1 methionine import ATP-binding protein Not tested Not named Protein 1e-60 44