Gene Information

Name : nrdF (MMAR_1647)
Accession : YP_001849952.1
Strain : Mycobacterium marinum M
Genome accession: NC_010612
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : -
Position : 1992809 - 1993783 bp
Length : 975 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
GTGACTGGAAATGCAAAGCTGATCGACCGCGTCTCCGCGATCAACTGGAACCGCGTCCAAGACGAGAAAGACGCCGAGGT
CTGGGACCGGTTGACCGGCAACTTCTGGCTGCCCGAGAAGGTCCCGGTATCCAACGACATCCCCTCCTGGGGCACGCTGA
CCGCCGGTGAAAAGCAGCTGACCATGCGGGTGTTCACGGGTCTGACGATGCTGGACACGATTCAGGGCACCGTGGGTGCG
GTCAGCTTGATCCCCGACGCGCTGACTCCCCACGAGGAGGCGGTGCTGACCAACATCGCGTTCATGGAGTCGGTGCACGC
CAAGAGCTACAGCCAGATTTTCTCCACCCTGTGCTCGACCGCCGAGATTGACGACGCGTTCCGCTGGTCGGAGGAAAACT
CCAACCTGCAGCGCAAGGCGGAGATCGTGCTCGAGTACTACCGGGGCGATGACCCGCTCAAGCGCAAGGTGGCCTCCACG
CTGCTGGAAAGCTTCCTGTTCTACTCGGGCTTCTACCTGCCGATGTACTGGTCGAGCCGGGCCAAGCTGACCAACACGGC
TGACATGATCCGGCTGATCATCCGCGATGAGGCCGTGCACGGCTACTACATCGGCTACAAGTTCCAGCGCGGGCTTGCGG
CCGCCGACGAGGCCCGGCGTACCGAGCTCAAGGACTACACCTACGAGCTGCTCTTCGAGCTATACGACAACGAAGTCGAG
TACACCCAGGATCTCTACGACGAGGTCGGGCTGACCGAGGATGTCAAGAAGTTCTTGCGCTACAACGCAAACAAGGCGTT
GATGAACCTCGGCTACGAGGCCCTGTTCCCGCGCGATGAGACCGACGTGAACCCGGCGATCCTTTCGGCGCTGTCGCCGA
ATGCCGACGAGAACCACGACTTCTTCTCCGGCTCGGGGTCGAGCTACGTGATCGGCAAGGCCGTGGTCACTCAAGACGAG
GACTGGGACTTCTAG

Protein sequence :
MTGNAKLIDRVSAINWNRVQDEKDAEVWDRLTGNFWLPEKVPVSNDIPSWGTLTAGEKQLTMRVFTGLTMLDTIQGTVGA
VSLIPDALTPHEEAVLTNIAFMESVHAKSYSQIFSTLCSTAEIDDAFRWSEENSNLQRKAEIVLEYYRGDDPLKRKVAST
LLESFLFYSGFYLPMYWSSRAKLTNTADMIRLIIRDEAVHGYYIGYKFQRGLAAADEARRTELKDYTYELLFELYDNEVE
YTQDLYDEVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAILSALSPNADENHDFFSGSGSSYVIGKAVVTQDE
DWDF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 6e-116 74