Gene Information

Name : nrdE (MMAR_1642)
Accession : YP_001849947.1
Strain : Mycobacterium marinum M
Genome accession: NC_010612
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : -
Position : 1986947 - 1989112 bp
Length : 2166 bp
Strand : +
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
GTGTCACCAACCGTCACTGCAGAGCCTGTAACCACCAGCGCGCACGCGCTGCCGGGGGAAACGGACTACCACGCGCTCAA
CGCGATGCTGAATCTGTACGACGCGGACGGCAAGATTCAGTTCGACAGGGACGTTCTTGCCGCACGTCAGTTTTTCCTGC
AGCACGTCAACCAGAACACGGTCTTCTTCCATAACCAGGACGAGAAGCTCGACTATCTGATCCGCGAGAACTACTACGAG
CGTGAGGTGCTCGATCAGTACTCGCGCAACTTCGTCAAGACGCTGCTCGATCGCGCCTATGCAAAGAAGTTCCGGTTCCC
GACGTTCTTGGGGGCGTTCAAGTACTACACCTCCTACACGTTGAAGACCTTCGACGGCAAGCGCTACCTGGAACGCTTCG
AGGACCGCGTGGTCATGGTGGCGCTGACGCTGGCCTCCGGTGACGCGACGTTGGCCGAGAAGCTCGTCGACGAAATCATC
GACGGTCGGTTCCAGCCGGCCACGCCGACCTTTTTGAACTCCGGCAAGAAGCAGCGCGGCGAGCCGGTGAGCTGCTTTCT
GCTGCGCATCGAGGACAACATGGAGTCGATCGGACGATCGATCAACTCCGCGTTGCAGCTGTCCAAGCGGGGTGGGGGAG
TAGCGCTGCTGCTGACCAACATCCGCGAGCATGGTGCGCCGATCAAAAACATCGAGAATCAGTCGTCGGGCGTCATCCCG
ATCATGAAGCTGCTCGAGGACTCGTTCTCCTACGCCAATCAGCTGGGGGCGCGTCAGGGTGCCGGCGCGGTGTACCTGCA
CGCGCACCATCCCGACATCTACCGCTTCCTGGACACCAAGCGCGAGAACGCCGACGAGAAGATCCGGATCAAGACCCTGA
GCCTGGGGGTGGTGATCCCGGACATCACCTTCGAGTTGGCCAAGCGCAACGACGACATGTACCTCTTCTCGCCCTACGAC
GTCGAACGCGTCTACGGTGTGCCGTTCGCCGACATCTCGGTGACCGAGAAGTACTACGAGATGGTCGACGACTCGCGCAT
CCGCAAGACCAAGATCAAAGCGCGAGAGTTCTTTCAGACGCTGGCCGAGCTGCAGTTCGAGTCCGGCTACCCCTACATCA
TGTTCGAAGACACGGTGAACCGGGCCAACCCCATTGAGGGCAAGATCACCCACAGCAACCTGTGCTCGGAGATCCTGCAG
GTGTCCACGCCGTCGTTGTTCAACGACGACTTGTCGTACGCCAAGGTGGGCAAGGACATTTCCTGCAACCTGGGCTCACT
GAACATCGCCAGGACCATGGATTCCCCGGACTTCGCCCAGACCATCGAGGTGGCGATCCGGGCGCTGACGGCGGTCAGCG
ACCAGACGCACATCACCTCGGTGCCCTCAATCGAGCAGGGGAACAACGACTCCCACGCCATCGGTCTGGGACAGATGAAC
CTGCACGGCTACCTGGCCCGCGAACACATCTTCTACGGCTCCGAAGAAGGCGTTGACTTCACCAACATCTACTTCTATGC
GGTGCTCTACCACGCGCTGCGGGCGTCCAACCGAATCGCGGTCGAACGCGGCACGCGCTTCAAGGGTTTCGACCAATCCA
AGTACGCATCGGGGGAGTTCTTCGACAAGTACACCGAACGGGTTTGGGAGCCGAAAACCGAGAAGGTGCGCCAGCTCTTC
GCCGACGCGGGCATCCGCATTCCCAACCAGGACGACTGGCAGCGGTTGAAGGAGTCCGTGCAAGCTCACGGCATCTACAA
CCAGAACCTGCAAGCGGTGCCGCCGACCGGGTCGATTTCCTACATCAACCACTCGACCTCGTCGATCCACCCCATCGTCT
CCAAGGTCGAGATCCGCAAAGAAGGCAAGATCGGTCGCGTCTACTACCCGGCGCCCTACATGACCAACGAGAACCTGGAC
TACTACCAGGATGCCTATGAAATCGGCTACGAGAAGATCATCGACACCTATGCGGCCGCCACTGAGCATGTGGACCAAGG
GCTTTCGTTGACGTTGTTCTTCAAGGACACCGCCACCACCCGCGACGTCAACAAGGCGCAGATTTACGCCTGGCGCAAAG
GGATCAAAACCCTGTACTACATCAGGCTGCGGCAGATGGCGCTGGAGGGAACCGAGGTCGCCGGCTGCGTGTCCTGCATG
CTCTAG

Protein sequence :
MSPTVTAEPVTTSAHALPGETDYHALNAMLNLYDADGKIQFDRDVLAARQFFLQHVNQNTVFFHNQDEKLDYLIRENYYE
REVLDQYSRNFVKTLLDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKRYLERFEDRVVMVALTLASGDATLAEKLVDEII
DGRFQPATPTFLNSGKKQRGEPVSCFLLRIEDNMESIGRSINSALQLSKRGGGVALLLTNIREHGAPIKNIENQSSGVIP
IMKLLEDSFSYANQLGARQGAGAVYLHAHHPDIYRFLDTKRENADEKIRIKTLSLGVVIPDITFELAKRNDDMYLFSPYD
VERVYGVPFADISVTEKYYEMVDDSRIRKTKIKAREFFQTLAELQFESGYPYIMFEDTVNRANPIEGKITHSNLCSEILQ
VSTPSLFNDDLSYAKVGKDISCNLGSLNIARTMDSPDFAQTIEVAIRALTAVSDQTHITSVPSIEQGNNDSHAIGLGQMN
LHGYLAREHIFYGSEEGVDFTNIYFYAVLYHALRASNRIAVERGTRFKGFDQSKYASGEFFDKYTERVWEPKTEKVRQLF
ADAGIRIPNQDDWQRLKESVQAHGIYNQNLQAVPPTGSISYINHSTSSIHPIVSKVEIRKEGKIGRVYYPAPYMTNENLD
YYQDAYEIGYEKIIDTYAAATEHVDQGLSLTLFFKDTATTRDVNKAQIYAWRKGIKTLYYIRLRQMALEGTEVAGCVSCM
L

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 0.0 79