Gene Information

Name : thyA (ACICU_00468)
Accession : YP_001845127.1
Strain : Acinetobacter baumannii ACICU
Genome accession: NC_010611
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : -
Position : 514146 - 514988 bp
Length : 843 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGCGTGCATATTTAGACCTTCTACAACATATCCTTGATAATGGCGGTGACAAAGGCGACCGTACAGGCACAGGAACCCG
TTCTGTATTTGGTCATCAAATGCGTTTTGATCTCTCTAAGGGTTTTCCTTTACTCACCACAAAAAAAGTTCACTTTCGTT
CTATCGTGATTGAGTTACTTTGGTTCTTAAAAGGCGATACTAACGTTAAGTACTTACAAGACAATAAAGTCACCATTTGG
GATGAATGGGCAACAGCAGAACAAACTGCCCGTTTCGGCCGCCCAGAACATGAGCTTGGCCCAGTTTATGGCCATCAATG
GCGTAATTTCGGCGCAACTAAAAATGCCGATGGTACTTATAACCAAGATGGTTTTGACCAAATTAAATGGTTAATTAATG
AAATTAAAACCAACCCAAATTCACGCCGTTTAATTGTCTCTGGCTGGAACCCAAATGAGGCTGGACAAGTTGCTTTACCG
CCTTGCCATACGCTCTTCCAATTCTTCGTACAAGACAACAAGTTGTCATGCCAGCTTTATCAACGTAGTGCTGACGTATT
CTTAGGCGTGCCATTTAATATTGCCAGCTATGCCCTACTCACCCATATGATTGCTCAAGTGTGTGGCTTAGGTGTTGGTG
ATTTTGTTTGGACAGGTGGCGATACGCATCTTTATGCCAACCATTTTGAGCAGGCAAAACTACAATTGACGCGTGAGCCA
TTACCACTTTGCCAATTAAAACTTAATCCGGATGTTAAAGATATTTTCGACTTCAAATTTGAAGACATCGAGATTGTAGG
TTACGAGTCACATCCGGCAATTAAAGCACCAGTTGCAGTATAA

Protein sequence :
MRAYLDLLQHILDNGGDKGDRTGTGTRSVFGHQMRFDLSKGFPLLTTKKVHFRSIVIELLWFLKGDTNVKYLQDNKVTIW
DEWATAEQTARFGRPEHELGPVYGHQWRNFGATKNADGTYNQDGFDQIKWLINEIKTNPNSRRLIVSGWNPNEAGQVALP
PCHTLFQFFVQDNKLSCQLYQRSADVFLGVPFNIASYALLTHMIAQVCGLGVGDFVWTGGDTHLYANHFEQAKLQLTREP
LPLCQLKLNPDVKDIFDFKFEDIEIVGYESHPAIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 1e-67 58
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 1e-65 51