Gene Information

Name : ACICU_00274 (ACICU_00274)
Accession : YP_001844933.1
Strain : Acinetobacter baumannii ACICU
Genome accession: NC_010611
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 297495 - 299372 bp
Length : 1878 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAACCAATTAACGAATCTCTCTTCTGCTGAAATTTCAGCACAACATGAACAAGATGCAAAAGACTTAACCCGCATCTT
ACCCGCTTCTAAAAAAGTTTATATTGAAGGCTCTCGCCCTGATATTCAGGTTCCAATGCGAGAAATTTCTTTAACCGATA
CCCCAACTGGCCTTGGTGGTGAGCACAACCCACCTATTATGGTATATGACACTTCAGGTGTTTATACTGACCCGAATGTT
CAAATTGATTTAAACAAAGGTTTACCTTCAGTTCGTCAAAAATGGATTGAAGAGCGTAACGATACTGACGTTCTTTCTGG
CCTAACTTCAAAGTTTGGACAGGAGCGTTTAAAAGATATTCGTACTGCTGATATTCGCTTTGCACATATTCAAAACCCAC
GCCGCGCTAAAGCAGGCAAAAATGTCACTCAAATGCACTATGCCAAGCAAGGTATTATCACGCCTGAAATGGAATATATT
GCAATTCGTGAAAATCAGCGTCAACGCGAAGCTGTAGATATGCGCCAGCACCCAGGTCAAAACTTTGGTGCGAAAAACTT
AAAAGAAATTACACCTGAGTTTGTTCGCCAAGAAGTTGCCGAAGGCCGCGCTATTATTCCTGCCAACATTAACCACCCAG
AACTTGAACCAATGATTATTGGCCGTAATTTCTTGGTTAAGATTAATGCCAATATTGGTAACTCGGCGCTTGGTTCTTCA
ATTGATGAAGAAGTTGCGAAAATGACATGGGCAACCCGTTGGGGCGCTGACACCATTATGGACTTGTCTACAGGTAAGAA
CATTCATGAAACACGTGAATGGATTATTCGTAACTCACCAGTTCCAATCGGTACCGTACCAATTTATCAAGCACTTGAAA
AAGTTGATGGTGTTGCCGAGAACCTGACTTGGGAAATCTTTAAAGACACGCTTATTGAACAAGCTGAACAAGGTGTTGAC
TACTTCACCATTCACGCAGGTGTTCTACTTCGTTATGTGCCACTTACAGCAAACCGTTTAACAGGTATTGTGTCTCGTGG
TGGTTCAATCATGGCGCAGTGGTGTCTCGCTCATCATGAAGAGAACTTCTTATACACACACTTCGATGAAATCTGTGAAA
TCATGAAAGCCTATGATGTGTCATTTAGCTTAGGCGATGGCTTACGTCCGGGTTGTATTCAAGATGCAAATGACGAAGCG
CAGTTCAGCGAACTTAAAACACTGGGTGAGCTGACTCACCGTGCATGGGAACATGATGTTCAGGTCATGATTGAAGGTCC
GGGTCATGTACCAATGCACATGATTAAAGAGAACATGGACTTACAGTTAGAAGTGTGTAAAGAAGCTCCATTCTATACGC
TTGGACCTTTAACCACAGATATCGCTCCGGGTTATGACCACATTACTTCTGCTATTGGTGCAGCCATGATTGGCTGGTAT
GGCACAGCAATGCTTTGCTATGTGACACCTAAAGAACATTTAGGTTTACCAAACAAGAAAGATGTGAAAGACGGAATTAT
TACCTACAAGATTGCAGCACACGCAGCCGATCTTGCCAAAGGTCATCCGGGTGCACAGGTTCGTGATAATGCCTTGTCTA
AAGCACGTTTCGAATTCCGTTGGGACGACCAGTTCAACCTAAGTCTAGACCCAGATACAGCACGCAGCATGCATGACGAG
ACTTTACCAAAAGAAGCGCATAAATCTGCTCACTTTTGCTCAATGTGTGGTCCAAAATTCTGTTCGATGAAAATCACCCA
GAATGTACGTGACTATGCCAACAATCTCACCAATAGCGATTCAGAGGTTGAAGAAGGCCTCAAAGCAATGAAAGAGGTTT
ATCAAGAGCAAGGACAAAAACTGTATCATAAAGTGTAA

Protein sequence :
MNQLTNLSSAEISAQHEQDAKDLTRILPASKKVYIEGSRPDIQVPMREISLTDTPTGLGGEHNPPIMVYDTSGVYTDPNV
QIDLNKGLPSVRQKWIEERNDTDVLSGLTSKFGQERLKDIRTADIRFAHIQNPRRAKAGKNVTQMHYAKQGIITPEMEYI
AIRENQRQREAVDMRQHPGQNFGAKNLKEITPEFVRQEVAEGRAIIPANINHPELEPMIIGRNFLVKINANIGNSALGSS
IDEEVAKMTWATRWGADTIMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVDGVAENLTWEIFKDTLIEQAEQGVD
YFTIHAGVLLRYVPLTANRLTGIVSRGGSIMAQWCLAHHEENFLYTHFDEICEIMKAYDVSFSLGDGLRPGCIQDANDEA
QFSELKTLGELTHRAWEHDVQVMIEGPGHVPMHMIKENMDLQLEVCKEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWY
GTAMLCYVTPKEHLGLPNKKDVKDGIITYKIAAHAADLAKGHPGAQVRDNALSKARFEFRWDDQFNLSLDPDTARSMHDE
TLPKEAHKSAHFCSMCGPKFCSMKITQNVRDYANNLTNSDSEVEEGLKAMKEVYQEQGQKLYHKV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 100
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 100
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 72