Gene Information

Name : guaA (ACICU_00155)
Accession : YP_001844814.1
Strain : Acinetobacter baumannii ACICU
Genome accession: NC_010611
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 178591 - 180159 bp
Length : 1569 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACTACCAATACTCAAATTACTGAAGATCGTATCCTGATCCTGGATTTCGGCTCTCAATATAGTCAGCTCATTGCACG
TCGTGTACGTGAAGCTGGTGTTTACTCTGAAATGTATGCCTTTGATATGTCTGAAGAAGACATCCGTGCTTTTAAGCCAA
ACGGTATCATTTTATCAGGTGGACCTGAGAGTGTGCATGAAGAGGGCAGCCCTCGCGCACCGCAAGTGGTGTTTGAATTA
GGCGTTCCAGTATTGGGTATTTGCTATGGTTTACAAACCATGTCTGAACAGTTAGGCGGTAAAGTTGAGCCGGGTACTGT
ACATGAGTTTGGTTATGCCGAAGTTGATATCGTTAAACGTGACCAACTTATTGGCAACTTACAAGACCGCGAAAACCAAC
TACACGTTTGGATGAGCCACGGCGACAAAGTGAGCCAGATTCCAGAAGGTTTTACGATTACTGCAAGCACACCAAGCTGT
CCAGTTGCTGCTGTAAGTGATGAAACACGCCGTTTTTACGGTGTTCAGTTCCACCCAGAAGTAACACACACGGCAAAAGG
TGAAGAGCTACTTTCTAATTTCGTTCACAAAATTTGTGGATGCGGTGGCCTTTGGACACCTGAACACATCATCGATTTGC
GTGTAGAGCAGTTACGTGAGCAAATTGGTAACGAGAAAGTACTTTTAGGCCTGTCTGGTGGTGTTGACTCATCTGTTGTT
GCTGCGCTTTTACACAAAGCGATTGGTGACCAATTAACATGTGTATTTGTTGATAATGGTTTGCTTCGTTTAAACGAAGG
TGACCAAGTGATGCAAATGTTTGCTGAAAACATGGGTATTCGTGTTATTCGTGCAGATGCAGAAGCACGTTTCTTAAATG
CTCTAGCTGGCGTTACCGATCCTGAAGCGAAGCGTAAAATTATTGGTCGTGAGTTTATTGAAGTATTTGCTGAAGAAGCA
CGTAAACTTGATGGCGTGAAATTCTTGGCGCAAGGTACAATTTACCCAGACGTAATTGAATCTGCTGCAAGCAAACAAGG
TAAAGCACACGTTATTAAATCTCACCACAATGTGGGTGGTTTACCAGACGATTTAGCATTTGAATTGGTTGAGCCTTTAC
GTGACTTGTTTAAAGATGAAGTACGTAAATTAGGTACTACACTTGGTTTACCGCACAGCATGATCTATCGTCATCCATTC
CCGGGCCCTGGTTTAGGCGTTCGTATTTTGGGTGAAGTGAAAAAAGAATATGCAGATATTCTTCGTCTTGCTGATGATAT
CTTTATGCAAGAGCTTCGTGACAGCGGCTGGTATGACAAAACAGCTCAAGCATTTGCTGTATTCCAACCTGTTAAATCAG
TAGGTGTAGTCGGTGATGGCCGACGCTATGCATGGGTGATTGCGCTTCGTGCAGTTGAAACAGTTGACTTTATGACAGCT
CGTTTTGCACATTTACCATACGAATTGGTTGATAAAATCTCAACACGCATTATGAACGAAATTAAAGATGTATCACGTGT
GGTATACGACGTGTCATCTAAACCACCAGCAACGATTGAGTGGGAATAA

Protein sequence :
MTTNTQITEDRILILDFGSQYSQLIARRVREAGVYSEMYAFDMSEEDIRAFKPNGIILSGGPESVHEEGSPRAPQVVFEL
GVPVLGICYGLQTMSEQLGGKVEPGTVHEFGYAEVDIVKRDQLIGNLQDRENQLHVWMSHGDKVSQIPEGFTITASTPSC
PVAAVSDETRRFYGVQFHPEVTHTAKGEELLSNFVHKICGCGGLWTPEHIIDLRVEQLREQIGNEKVLLGLSGGVDSSVV
AALLHKAIGDQLTCVFVDNGLLRLNEGDQVMQMFAENMGIRVIRADAEARFLNALAGVTDPEAKRKIIGREFIEVFAEEA
RKLDGVKFLAQGTIYPDVIESAASKQGKAHVIKSHHNVGGLPDDLAFELVEPLRDLFKDEVRKLGTTLGLPHSMIYRHPF
PGPGLGVRILGEVKKEYADILRLADDIFMQELRDSGWYDKTAQAFAVFQPVKSVGVVGDGRRYAWVIALRAVETVDFMTA
RFAHLPYELVDKISTRIMNEIKDVSRVVYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-142 55
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-142 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-142 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 5e-118 50